{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T17:55:49Z","timestamp":1774374949314,"version":"3.50.1"},"reference-count":37,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Xenobiotica"],"published-print":{"date-parts":[[2023,3,4]]},"DOI":"10.1080\/00498254.2023.2200524","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T13:22:12Z","timestamp":1681305732000},"page":"184-192","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":3,"title":["Dose-dependent pharmacokinetics of midazolam in rats: influence of hepatic first-pass metabolism"],"prefix":"10.1080","volume":"53","author":[{"given":"Run","family":"Li","sequence":"first","affiliation":[{"name":"Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingqing","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zihou","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Like","family":"Xie","sequence":"additional","affiliation":[{"name":"Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhipeng","family":"Diao","sequence":"additional","affiliation":[{"name":"Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Peng","sequence":"additional","affiliation":[{"name":"Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangji","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianguo","family":"Sun","sequence":"additional","affiliation":[{"name":"Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2023,4,27]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1023\/A:1023429401738"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.110.035824"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.105.008730"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(95)02107-8"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.112.049593"},{"issue":"9","key":"CIT0005","first-page":"940","volume":"24","author":"Ghosal A","year":"1996","journal-title":"Drug Metab Dispos"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1002\/jps.22675"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1211\/0022357991771971"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-016-9890-5"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.2133\/dmpk.DMPK-14-RG-020"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2003.12.039"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1080\/00498250500093786"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(01)00843-7"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.102.035972"},{"issue":"1","key":"CIT0015","first-page":"89","volume":"36","author":"Kronbach T","year":"1989","journal-title":"Mol Pharmacol"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.3109\/00498250903215382"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1177\/0091270005283466"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics11070318"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.12730"},{"issue":"3","key":"CIT0020","first-page":"296","volume":"22","author":"Lin Y","year":"2019","journal-title":"Iran J Basic Med Sci"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.110.036400"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.2133\/dmpk.18.252"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.106.013037"},{"issue":"05","key":"CIT0024","first-page":"834","volume":"51","author":"Qin X","year":"2016","journal-title":"Acta Pharmaceutica Sinica"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600570123"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1080\/00498250701851891"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.110.037903"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1023\/A:1016217221977"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.3109\/00498254.2012.655703"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9236(96)90177-0"},{"issue":"1","key":"CIT0031","first-page":"549","volume":"271","author":"Thummel KE","year":"1994","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2021.122892"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.3109\/00498254.2012.684104"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/73.5.658"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-004-9004-4"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1186082"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-018-2470-x"}],"container-title":["Xenobiotica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/00498254.2023.2200524","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T19:47:31Z","timestamp":1686080851000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/00498254.2023.2200524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,4]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3,4]]}},"alternative-id":["10.1080\/00498254.2023.2200524"],"URL":"https:\/\/doi.org\/10.1080\/00498254.2023.2200524","relation":{},"ISSN":["0049-8254","1366-5928"],"issn-type":[{"value":"0049-8254","type":"print"},{"value":"1366-5928","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ixen20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ixen20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2023-02-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-03","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}