{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T04:02:48Z","timestamp":1793419368543,"version":"4.5.0"},"reference-count":30,"publisher":"Informa UK Limited","issue":"5","funder":[{"name":"Japan Research Foundation for JSPS Kakenhi"},{"name":"United States National Institutes of Health"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Xenobiotica"],"published-print":{"date-parts":[[2023,5,4]]},"DOI":"10.1080\/00498254.2023.2248498","type":"journal-article","created":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T10:19:23Z","timestamp":1692181163000},"page":"357-365","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":4,"title":["The influence of temperature on the metabolic activity of CYP2C9, CYP2C19, and CYP3A4 genetic variants\n                    <i>in\u00a0vitro<\/i>"],"prefix":"10.1080","volume":"53","author":[{"given":"Michiaki","family":"Kojima","sequence":"first","affiliation":[{"name":"Division of Clinical Pharmacokinetics, Faculty of Pharmacy, Keio University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanami","family":"Machida","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacokinetics, Faculty of Pharmacy, Keio University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumie","family":"Cho","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacokinetics, Faculty of Pharmacy, Keio University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daichi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Seki","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miyuki","family":"Shimoji","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of the Ryukyus Hospital, Okinawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayuko","family":"Imaoka","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacokinetics, Faculty of Pharmacy, Keio University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1068-4261","authenticated-orcid":false,"given":"Hiroshi","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Tokyo, Machida, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. Peter","family":"Guengerich","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsunori","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of the Ryukyus Hospital, Okinawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koujirou","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Gunma University Graduate School of Medicine, Gunma, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Akiyoshi","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacokinetics, Faculty of Pharmacy, Keio University, Tokyo, Japan"},{"name":"Division of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan"},{"name":"Division of Clinical Pharmacokinetics, School of Medicine, Keio University, Tokyo, Shinjuku, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisakazu","family":"Ohtani","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacokinetics, Faculty of Pharmacy, Keio University, Tokyo, Japan"},{"name":"Division of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan"},{"name":"Division of Clinical Pharmacokinetics, School of Medicine, Keio University, Tokyo, Shinjuku, Japan"},{"name":"Department of Pharmacy, Keio University Hospital, Tokyo, Shinjuku, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,8,23]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/ther.2016.0003"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000001432"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1254\/fpj.112.15"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31823779f9"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e318292316c"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1993.1401"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-2952(97)00643-6"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10528-016-9771-8"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/004982598239236"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2015.12.035"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.41.1.535"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.1960"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.108.021816"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2019.05.007"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.2133\/dmpk.17.150"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(20)82245-5"},{"key":"e_1_3_4_18_1","unstructured":"PharmVar. https:\/\/www.pharmvar.org\/gene\/CYP2C19. last accessed: 2023\/3\/06"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.112573"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.01126"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21568"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117582"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199223030-00006"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008571-199608000-00007"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/tpj.2014.30"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.110.037549"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dmpk.2021.100384"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb1978.4.879"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2012.12.007"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/03602530902843483"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.2334"}],"container-title":["Xenobiotica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/00498254.2023.2248498","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T06:07:31Z","timestamp":1696486051000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/00498254.2023.2248498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,4]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5,4]]}},"alternative-id":["10.1080\/00498254.2023.2248498"],"URL":"https:\/\/doi.org\/10.1080\/00498254.2023.2248498","relation":{},"ISSN":["0049-8254","1366-5928"],"issn-type":[{"value":"0049-8254","type":"print"},{"value":"1366-5928","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ixen20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ixen20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2023-04-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}