{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:54:36Z","timestamp":1792785276704,"version":"4.5.0"},"reference-count":61,"publisher":"Informa UK Limited","issue":"2","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"funder":[{"name":"Henan Province Medical Science and Technology Research Program Joint Construction Project","award":["LHGJ20230714"],"award-info":[{"award-number":["LHGJ20230714"]}]},{"name":"Henan Provincial Joint Research Program of Science and Technology for Key Projects","award":["225200810011"],"award-info":[{"award-number":["225200810011"]}]},{"name":"Key Scientific Research Projects of Colleges and Universities in Henan province","award":["26B310010"],"award-info":[{"award-number":["26B310010"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Drug and Chemical Toxicology"],"published-print":{"date-parts":[[2026,3,4]]},"DOI":"10.1080\/01480545.2025.2606908","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T04:32:02Z","timestamp":1769142722000},"page":"344-355","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["Integrated network toxicology, machine learning, and bioinformatics analysis reveals sodium dehydroacetate-induced coagulation dysfunction in colorectal cancer"],"prefix":"10.1080","volume":"49","author":[{"given":"Zhenzhen","family":"Yang","sequence":"first","affiliation":[{"name":"The Fifth Clinical Medical College of Henan University of Chinese Medicine (Zhengzhou People\u2019s Hospital)","place":["Zhengzhou, P.R. China"]},{"name":"School of Basic Medical Sciences, Zhengzhou University","place":["Zhengzhou, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Chang","sequence":"additional","affiliation":[{"name":"Zhengzhou Urban Construction Vocational College","place":["Zhengzhou, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liya","family":"Jiang","sequence":"additional","affiliation":[{"name":"Zhengzhou Urban Construction Vocational College","place":["Zhengzhou, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfeng","family":"Li","sequence":"additional","affiliation":[{"name":"The Fifth Clinical Medical College of Henan University of Chinese Medicine (Zhengzhou People\u2019s Hospital)","place":["Zhengzhou, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Gao","sequence":"additional","affiliation":[{"name":"The Fifth Clinical Medical College of Henan University of Chinese Medicine (Zhengzhou People\u2019s Hospital)","place":["Zhengzhou, P.R. China"]},{"name":"School of Basic Medical Sciences, Zhengzhou University","place":["Zhengzhou, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Fifth Clinical Medical College of Henan University of Chinese Medicine (Zhengzhou People\u2019s Hospital)","place":["Zhengzhou, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinsen","family":"Song","sequence":"additional","affiliation":[{"name":"The Fifth Clinical Medical College of Henan University of Chinese Medicine (Zhengzhou People\u2019s Hospital)","place":["Zhengzhou, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianli","family":"Fan","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Zhengzhou University","place":["Zhengzhou, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-021-01458-1"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.22.7199"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature03357"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2024014190"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jat.4156"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.727084"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2019.05.002"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/10915818241260276"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2021.01.1605"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0266267"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2687"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2020-0324-SA"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12575"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-020-01350-4"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.15414"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-019-02161-8"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-43156-2_10"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/16078454.2024.2377849"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2020.111613"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/19440049.2019.1615644"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1248\/cpb.c17-00938"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.4238\/2014.March.17.13"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2025.115469"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.68650"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2021.118190"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/land14061232"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.8526"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.584057"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112152-20200709-00633"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp003020w"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2012.04865.x"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jointm.2021.09.002"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/16078454.2020.1730080"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2022.03.048"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10068-017-0238-4"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1572701"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020007208"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2023.11.013"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1328881"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1080\/19393210.2017.1412360"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mucimm.2024.12.001"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X221101654"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbae032"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.21037\/cdt.2017.09.01"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon.13.179"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-018-2413-z"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/46.8.1260"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-025-03296-1"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.161271"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002787"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2023.102482"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.134865"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.2366"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/iub.2777"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2024.103834"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41538-024-00361-z"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2023.12.009"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202000383"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21040458"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2022.105518"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2024.141825"}],"container-title":["Drug and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/01480545.2025.2606908","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/01480545.2025.2606908","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/01480545.2025.2606908","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T06:51:15Z","timestamp":1781851875000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/01480545.2025.2606908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,22]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3,4]]}},"alternative-id":["10.1080\/01480545.2025.2606908"],"URL":"https:\/\/doi.org\/10.1080\/01480545.2025.2606908","relation":{},"ISSN":["0148-0545","1525-6014"],"issn-type":[{"value":"0148-0545","type":"print"},{"value":"1525-6014","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,22]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=idct20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=idct20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-09-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-10","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}