{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:23:38Z","timestamp":1788200618631,"version":"build-2803163510"},"reference-count":37,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Orbit"],"published-print":{"date-parts":[[2026,1,2]]},"DOI":"10.1080\/01676830.2025.2534963","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T13:03:08Z","timestamp":1756818188000},"page":"25-39","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":2,"title":["The use of tranexamic acid in external dacryocystorhinostomy: a systematic review and meta-analysis of randomized controlled trials"],"prefix":"10.1080","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1987-6048","authenticated-orcid":false,"given":"Saleha","family":"Azeem","sequence":"first","affiliation":[{"name":"King Edward Medical University","place":["Lahore, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7792-2229","authenticated-orcid":false,"given":"Shameer Iqbal","family":"Ghuman","sequence":"additional","affiliation":[{"name":"King Edward Medical University","place":["Lahore, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6398-818X","authenticated-orcid":false,"given":"Ishmal","family":"Fatima Shahid","sequence":"additional","affiliation":[{"name":"King Edward Medical University","place":["Lahore, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9381-0106","authenticated-orcid":false,"given":"Muhammad Imaz","family":"Bhatti","sequence":"additional","affiliation":[{"name":"King Edward Medical University","place":["Lahore, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8958-3864","authenticated-orcid":false,"given":"Jawad","family":"Ahmad","sequence":"additional","affiliation":[{"name":"King Edward Medical University","place":["Lahore, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3596-6300","authenticated-orcid":false,"given":"Zainab","family":"Jamil","sequence":"additional","affiliation":[{"name":"King Edward Medical University","place":["Lahore, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abeeha","family":"Fatima","sequence":"additional","affiliation":[{"name":"King Edward Medical University","place":["Lahore, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1576-1330","authenticated-orcid":false,"given":"Azka","family":"Ijaz","sequence":"additional","affiliation":[{"name":"King Edward Medical University","place":["Lahore, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eilaf","family":"Azeem","sequence":"additional","affiliation":[{"name":"Department of Sciences, International School Lahore","place":["Lahore, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Ahmad","family":"Tariq","sequence":"additional","affiliation":[{"name":"Department of Sciences, Pakistan International School English Section","place":["Jeddah, Kingdom of Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,9,2]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(95)30910-4"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01452-5"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-023-02789-w"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.18231\/j.ijooo.2021.070"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_925_22"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.2165\/11209070-000000000-00000"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_3_4_9_1","unstructured":"Risk of bias 2 (RoB 2) tool | Cochrane methods. https:\/\/methods.cochrane.org\/risk-bias-2. Accessed March 29 2025."},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/XEB.0000000000000141"},{"key":"e_1_3_4_12_1","article-title":"An emerging consensus on rating quality of evidence and strength of recommendations","author":"GRADE","unstructured":"GRADE. An emerging consensus on rating quality of evidence and strength of recommendations. The BMJ. https:\/\/www.bmj.com\/content\/336\/7650\/924.","journal-title":"The BMJ"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39490.551019.BE"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.18502\/jovr.v19i3.13947"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.52547\/sjku.27.5.58"},{"key":"e_1_3_4_16_1","first-page":"177","article-title":"Comparison of tranexamic acid, remifentanil, and hydralazine on the bleeding volume during dacryocystorhinostomy surgery","volume":"14","author":"Moradi Farsani D","year":"2022","unstructured":"Moradi Farsani D, Shetabi H, Rafiee Zadeh A, Saffari Rad N. Comparison of tranexamic acid, remifentanil, and hydralazine on the bleeding volume during dacryocystorhinostomy surgery. Int J Physiol Pathophysiol Pharmacol. 2022;14:177\u2013186.","journal-title":"Int J Physiol Pathophysiol Pharmacol"},{"key":"e_1_3_4_17_1","unstructured":"Ullrich K Malhotra R Patel BC. Dacryocystorhinostomy. StatPearls. StatPearls Publishing. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557851\/. 2025. Accessed March 29 2025."},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215121003170"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2019.08.006"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.1381"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000015202"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpsam.2020.0590"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjab333"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jopan.2008.08.003"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2018.03.022"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2018.01.006"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000036407"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.5603\/DEMJ.a2022.0018"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2023.101049"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2021.12.027"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/2192568217701105"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15564"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/6753210"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20160301-05"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.10.213"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-022-05308-4"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/11206721241249214"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2012.152"}],"container-title":["Orbit"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/01676830.2025.2534963","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T12:12:00Z","timestamp":1769775120000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/01676830.2025.2534963"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,2]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,2]]}},"alternative-id":["10.1080\/01676830.2025.2534963"],"URL":"https:\/\/doi.org\/10.1080\/01676830.2025.2534963","relation":{},"ISSN":["0167-6830","1744-5108"],"issn-type":[{"value":"0167-6830","type":"print"},{"value":"1744-5108","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iorb20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iorb20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-05-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}