{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T12:59:38Z","timestamp":1778849978474,"version":"3.51.4"},"reference-count":138,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biotechnology and Genetic Engineering Reviews"],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1080\/02648725.2010.10648143","type":"journal-article","created":{"date-parts":[[2013,4,15]],"date-time":"2013-04-15T16:24:02Z","timestamp":1366043042000},"page":"1-32","source":"Crossref","is-referenced-by-count":17,"title":["Biosynthesis of active pharmaceuticals: \u03b2-lactam biosynthesis in filamentous fungi"],"prefix":"10.1080","volume":"27","author":[{"given":"Loknath","family":"Gidijala","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan A.K.W.","family":"Kiel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roel AL","family":"Bovenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ida J.","family":"Van Der Klei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco A Van Den","family":"Berg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1146\/annurev.mi.46.100192.002333","volume":"46","author":"Aharonowitz Y.","year":"1992","journal-title":"Annu Rev Microbiol"},{"key":"CIT0002","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/j.1432-1033.1993.tb18038.x","volume":"215","author":"Alvarez E.","year":"1993","journal-title":"Eur J Biochem"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/j.1749-6632.1954.tb40000.x","volume":"60","author":"Backus E. J.","year":"1954","journal-title":"Ann N Y Acad Sci"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1039\/np9880500129","volume":"5","author":"Baldwin J. E.","year":"1988","journal-title":"Nat Prod Rep"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1042\/bj2450831","volume":"245","author":"Baldwin J. E.","year":"1987","journal-title":"Biochem J"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.chembiol.2005.08.010","volume":"12","author":"Balibar C. J.","year":"2005","journal-title":"Chem Biol"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1126\/science.284.5413.486","volume":"284","author":"Belshaw P. J.","year":"1999","journal-title":"Science"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1046\/j.0014-2956.2001.02691.x","volume":"269","author":"Bergendahl V.","year":"2002","journal-title":"Eur J Biochem"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1007\/BF00393928","volume":"11","author":"Beri R. K.","year":"1987","journal-title":"Curr Genet"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1021\/bi951534t","volume":"35","author":"Borovok I.","year":"1996","journal-title":"Biochemistry"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1128\/MMBR.62.3.547-585.1998","volume":"62","author":"Brakhage A. A.","year":"1998","journal-title":"Microbiol Mol Biol Rev"},{"issue":"1","key":"CIT0012","first-page":"3","volume":"66","author":"Brakhage A. A.","year":"2008","journal-title":"Prog Drug Res"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/378416a0","volume":"378","author":"Brannigan J. A.","year":"1995","journal-title":"Nature"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1021\/ie50489a025","volume":"42","author":"Brown W. E.","year":"1950","journal-title":"Industrial & Engineering Chemistry"},{"key":"CIT0015","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0969-2126(02)00716-5","volume":"10","author":"Bruner S. D.","year":"2002","journal-title":"Structure"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1042\/bj0500168","volume":"50","author":"Burton H. S.","year":"1951","journal-title":"Biochem J"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/44400","volume":"401","author":"Burzlaff N. I.","year":"1999","journal-title":"Nature"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1021\/cr960018l","volume":"97","author":"Byford M. F.","year":"1997","journal-title":"Chem Rev"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1098\/rspb.1992.0073","volume":"248","author":"Cantwell C.","year":"1992","journal-title":"Proc Biol Sci"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/BF00312612","volume":"17","author":"Cantwell C. A.","year":"1990","journal-title":"Curr Genet"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s004380050847","volume":"259","author":"Casqueiro J.","year":"1998","journal-title":"Mol Gen Genet"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1128\/JB.181.4.1181-1188.1999","volume":"181","author":"Casqueiro J.","year":"1999","journal-title":"J Bacteriol"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/nature03194","volume":"432","author":"Clardy J.","year":"2004","journal-title":"Nature"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0167-7799(90)90148-Q","volume":"8","author":"Cohen G.","year":"1990","journal-title":"Trends Biotechnol"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1002\/bit.260460603","volume":"46","author":"Conlon H. D.","year":"1995","journal-title":"Biotechnol Bioeng"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"4174","DOI":"10.1093\/emboj\/16.14.4174","volume":"16","author":"Conti E.","year":"1997","journal-title":"Embo J"},{"key":"CIT0027","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1023\/A:1001738823146","volume":"75","author":"Demain A. L.","year":"1999","journal-title":"Antonie Van Leeuwenhoek"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1128\/AEM.1.2.103-106.1953","volume":"1","author":"Dulmage H. T.","year":"1953","journal-title":"Appl Microbiol"},{"key":"CIT0029","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s00253-003-1274-y","volume":"61","author":"Elander R. P.","year":"2003","journal-title":"Appl Microbiol Biotechnol"},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1006\/bbrc.1997.7107","volume":"237","author":"Etchegaray A.","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0031","first-page":"111","volume":"88","author":"Evers M. E.","year":"2004","journal-title":"Adv Biochem Eng Biotechnol"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1128\/AEM.59.4.1149-1154.1993","volume":"59","author":"Fernandez-Valverde M.","year":"1993","journal-title":"Appl Environ Microbiol"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"6200","DOI":"10.1073\/pnas.92.13.6200","volume":"92","author":"Fierro F.","year":"1995","journal-title":"Proc Natl Acad Sci U S A"},{"key":"CIT0034","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.fgb.2006.03.001","volume":"43","author":"Fierro F.","year":"2006","journal-title":"Fungal Genet Biol"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/BF00279899","volume":"241","author":"Fierro F.","year":"1993","journal-title":"Mol Gen Genet"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1007\/BF02221518","volume":"29","author":"Fierro F.","year":"1996","journal-title":"Curr Genet"},{"key":"CIT0037","first-page":"780","volume":"79","author":"Fleming A.","year":"1929","journal-title":"influenzae. Bull World Health Organ"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1042\/BJ20080369","volume":"415","author":"Garcia-Estrada C.","year":"2008","journal-title":"Biochem J"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.fgb.2008.03.005","volume":"45","author":"Garcia-Estrada C.","year":"2008","journal-title":"Fungal Genet Biol"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/1471-2180-9-104","volume":"9","author":"Garcia-Estrada C.","year":"2009","journal-title":"BMC Microbiol"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s002530000464","volume":"54","author":"Gellissen G.","year":"2000","journal-title":"Appl Microbiol Biotechnol"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0378-1119(97)00020-6","volume":"190","author":"Gellissen G.","year":"1997","journal-title":"Gene"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1472-6750-8-29","volume":"8","author":"Gidijala L.","year":"2008","journal-title":"BMC Biotechnol"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1111\/j.1567-1364.2007.00228.x","volume":"7","author":"Gidijala L.","year":"2007","journal-title":"FEMS Yeast Res"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/1471-2164-10-75","volume":"10","author":"Harris D. M.","year":"2009","journal-title":"BMC Genomics"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ymben.2008.12.003","volume":"11","author":"Harris D. M.","year":"2009","journal-title":"Metab Eng"},{"key":"CIT0047","first-page":"45","volume-title":"Biotechnology of industrial antibiotics","volume":"3","author":"Hersbach G.J.M.","year":"1984"},{"key":"CIT0048","volume-title":"Transport processes in penicillin biosynthesis","author":"Hillenga D.","year":"1999"},{"key":"CIT0049","author":"Hoff B.","year":"2009","journal-title":"Appl Microbiol Biotechnol"},{"key":"CIT0050","doi-asserted-by":"crossref","first-page":"12710","DOI":"10.1016\/S0021-9258(18)99934-5","volume":"269","author":"Hoffmann K.","year":"1994","journal-title":"J Biol Chem"},{"key":"CIT0051","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/S0958-1669(97)80028-6","volume":"8","author":"Hollenberg C. P.","year":"1997","journal-title":"Curr Opin Biotechnol"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.bbrc.2005.08.155","volume":"336","author":"Howard-Jones A. R.","year":"2005","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0053","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1016\/S0021-9258(18)97578-2","volume":"240","author":"Hung P. P.","year":"1965","journal-title":"J Biol Chem"},{"key":"CIT0054","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1534\/genetics.107.085795","volume":"178","author":"Hynes M. J.","year":"2008","journal-title":"Genetics"},{"key":"CIT0055","doi-asserted-by":"crossref","first-page":"7269","DOI":"10.1128\/jb.172.12.7269-7271.1990","volume":"172","author":"Jensen S. E.","year":"1990","journal-title":"J Bacteriol"},{"key":"CIT0056","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/bit.260460205","volume":"46","author":"Jorgensen H.","year":"1995","journal-title":"Biotechnol Bioeng"},{"key":"CIT0057","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1006\/jmbi.2000.3566","volume":"297","author":"Kallow W.","year":"2000","journal-title":"J Mol Biol"},{"key":"CIT0058","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S1570-9639(02)00427-2","volume":"1601","author":"Kallow W.","year":"2002","journal-title":"Biochim Biophys Acta"},{"key":"CIT0059","doi-asserted-by":"crossref","first-page":"5947","DOI":"10.1021\/bi971741o","volume":"37","author":"Kallow W.","year":"1998","journal-title":"Biochemistry"},{"key":"CIT0060","first-page":"522","volume":"9","author":"Keating T. A.","year":"2002","journal-title":"Nat Struct Biol"},{"key":"CIT0061","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1128\/AAC.17.4.679","volume":"17","author":"Kern B. A.","year":"1980","journal-title":"Antimicrob Agents Chemother"},{"key":"CIT0062","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s10142-009-0110-6","volume":"9","author":"Kiel J. A.","year":"2009","journal-title":"Funct Integr Genomics"},{"key":"CIT0063","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.fgb.2004.10.010","volume":"42","author":"Kiel J. A.","year":"2005","journal-title":"Fungal Genet Biol"},{"key":"CIT0064","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1111\/j.1600-0854.2006.00479.x","volume":"7","author":"Kiel J. A.","year":"2006","journal-title":"Traffic"},{"key":"CIT0065","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1128\/AEM.69.2.1308-1314.2003","volume":"69","author":"Kim C. F.","year":"2003","journal-title":"Appl Environ Microbiol"},{"key":"CIT0066","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ymben.2006.08.004","volume":"9","author":"Kleijn R. J.","year":"2007","journal-title":"Metab Eng"},{"key":"CIT0067","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1432-1033.1996.00335.x","volume":"236","author":"Kleinkauf H.","year":"1996","journal-title":"Eur J Biochem"},{"key":"CIT0068","author":"Koetsier M. J.","year":"2009","journal-title":"Fungal Genet Biol"},{"key":"CIT0069","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1042\/BJ20081257","volume":"417","author":"Koetsier M. J.","year":"2009","journal-title":"Biochem J"},{"key":"CIT0070","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1146\/annurev.bioeng.1.1.535","volume":"1","author":"Koffas M.","year":"1999","journal-title":"Annu Rev Biomed Eng"},{"key":"CIT0071","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1126\/science.1122928","volume":"312","author":"Koglin A.","year":"2006","journal-title":"Science"},{"key":"CIT0072","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1039\/b208333g","volume":"7","author":"Kohli R. M.","year":"2003","journal-title":"Chem Commun (Camb)"},{"key":"CIT0073","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0378-1119(88)90586-0","volume":"62","author":"Kolar M.","year":"1988","journal-title":"Gene"},{"key":"CIT0074","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1128\/jb.171.2.754-760.1989","volume":"171","author":"Kovacevic S.","year":"1989","journal-title":"J Bacteriol"},{"key":"CIT0075","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1128\/AEM.68.3.1211-1219.2002","volume":"68","author":"Laich F.","year":"2002","journal-title":"Appl Environ Microbiol"},{"key":"CIT0076","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1042\/BJ20051599","volume":"395","author":"Lamas-Maceiras M.","year":"2006","journal-title":"Biochem J"},{"key":"CIT0077","volume-title":"The Panlabs penicillin strain improvement program","author":"Lein J.","year":"1986"},{"key":"CIT0078","doi-asserted-by":"crossref","first-page":"15824","DOI":"10.1021\/bi011595t","volume":"40","author":"Linne U.","year":"2001","journal-title":"Biochemistry"},{"key":"CIT0079","doi-asserted-by":"crossref","first-page":"875?84","DOI":"10.1126\/science.173.4000.875","volume":"173","author":"Lipmann F.","year":"1971","journal-title":"Science"},{"key":"CIT0080","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.femsyr.2005.07.002","volume":"5","author":"Lutz M. V.","year":"2005","journal-title":"FEMS Yeast Res"},{"key":"CIT0081","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF00279362","volume":"235","author":"Mayorga M. E.","year":"1992","journal-title":"Mol Gen Genet"},{"key":"CIT0082","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1128\/AEM.9.4.349-353.1961","volume":"9","author":"Mindlin S. Z.","year":"1961","journal-title":"Streptomyces rimosus. Appl Microbiol"},{"key":"CIT0083","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/0304-4165(92)90118-E","volume":"1116","author":"Muller W. H.","year":"1992","journal-title":"Biochim Biophys Acta"},{"key":"CIT0084","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/1475-2859-8-45","volume":"13","author":"Naesby M.","year":"2009","journal-title":"Microb Cell Fact"},{"key":"CIT0085","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/sj.jim.2900411","volume":"19","author":"Newbert R. W.","year":"1997","journal-title":"J Ind Microbiol Biotechnol"},{"key":"CIT0087","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/j.fgb.2008.07.008","volume":"45","author":"Nijland J. G.","year":"2008","journal-title":"Fungal Genet Biol"},{"key":"CIT0088","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1021\/bi00889a017","volume":"3","author":"Okuda K.","year":"1964","journal-title":"Biochemistry"},{"key":"CIT0089","doi-asserted-by":"crossref","first-page":"6419","DOI":"10.1073\/pnas.95.11.6419","volume":"95","author":"Olivera E. R.","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"CIT0090","doi-asserted-by":"crossref","first-page":"5600","DOI":"10.1111\/j.1742-4658.2007.06081.x","volume":"274","author":"Otten L. G.","year":"2007","journal-title":"FEBS J"},{"key":"CIT0091","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1016\/j.febslet.2007.04.001","volume":"581","author":"Platta H. W.","year":"2007","journal-title":"FEBS Lett"},{"key":"CIT0092","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1021\/bi9719861","volume":"37","author":"Quadri L. E.","year":"1998","journal-title":"Biochemistry"},{"key":"CIT0093","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1146\/annurev.mi.32.100178.003113","volume":"32","author":"Queener S. W.","year":"1978","journal-title":"Annu Rev Microbiol"},{"key":"CIT0094","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1002\/bit.260220610","volume":"22","author":"Rhee D. K.","year":"1980","journal-title":"Biotechnol Bioeng"},{"key":"CIT0095","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1111\/j.1432-1033.1996.0736r.x","volume":"242","author":"Roach P. L.","year":"1996","journal-title":"Eur J Biochem"},{"key":"CIT0096","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.fgb.2005.01.014","volume":"42","author":"Rodr\u00edguez-S\u00e1iz M.","year":"2005","journal-title":"Fungal Genet Biol"},{"key":"CIT0097","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/sj.jim.2900370","volume":"18","author":"Romero J.","year":"1997","journal-title":"J Ind Microbiol Biotechnol"},{"key":"CIT0098","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1016\/j.bbamcr.2006.08.051","volume":"1763","author":"Schliebs W.","year":"2006","journal-title":"Biochim Biophys Acta"},{"key":"CIT0099","doi-asserted-by":"crossref","first-page":"23135","DOI":"10.1016\/S0021-9258(18)54473-2","volume":"266","author":"Schlumbohm W.","year":"1991","journal-title":"J Biol Chem"},{"key":"CIT0100","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S1074-5521(99)80050-7","volume":"6","author":"Shaw-Reid C. A.","year":"1999","journal-title":"Chem Biol"},{"key":"CIT0101","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/S1074-5521(02)00214-4","volume":"9","author":"Sieber S. A.","year":"2002","journal-title":"Chem Biol"},{"key":"CIT0102","author":"Siewers V.","year":"2009","journal-title":"Saccharomyces cerevisiae. Metab Eng"},{"key":"CIT0103","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.copbio.2004.06.006","volume":"15","author":"Sio C. F.","year":"2004","journal-title":"Curr Opin Biotechnol"},{"key":"CIT0104","doi-asserted-by":"crossref","first-page":"4495","DOI":"10.1046\/j.1432-1033.2002.03143.x","volume":"269","author":"Sio C. F.","year":"2002","journal-title":"Eur J Biochem"},{"key":"CIT0105","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.fgb.2009.02.008","volume":"46","author":"Snoek I. S.","year":"2009","journal-title":"Fungal Genet Biol"},{"key":"CIT0106","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1128\/EC.00374-08","volume":"8","author":"Sprote P.","year":"2009","journal-title":"Eukaryot Cell"},{"key":"CIT0107","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/j.1365-2958.2008.06422.x","volume":"70","author":"Sprote P.","year":"2008","journal-title":"Mol Microbiol"},{"key":"CIT0108","doi-asserted-by":"crossref","first-page":"22773","DOI":"10.1074\/jbc.273.35.22773","volume":"273","author":"Stachelhaus T.","year":"1998","journal-title":"J Biol Chem"},{"key":"CIT0109","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1126\/science.7604280","volume":"269","author":"Stachelhaus T.","year":"1995","journal-title":"Science"},{"key":"CIT0110","doi-asserted-by":"crossref","first-page":"5775","DOI":"10.1021\/bi9929002","volume":"39","author":"Stachelhaus T.","year":"2000","journal-title":"Biochemistry"},{"key":"CIT0111","doi-asserted-by":"crossref","first-page":"15428","DOI":"10.1074\/jbc.271.20.12017","volume":"271","author":"Stein T.","year":"1996","journal-title":"J Biol Chem"},{"key":"CIT0112","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1007\/s10529-009-9973-9","volume":"31","author":"Thakur D.","year":"2009","journal-title":"Biotechnol Lett"},{"key":"CIT0113","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/1097-0290(20000220)72:4<379::AID-BIT1000>3.0.CO;2-5","volume":"72","author":"Theilgaard H.","year":"2001","journal-title":"Biotechnol Bioeng"},{"key":"CIT0114","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1574-6968.1994.tb07073.x","volume":"121","author":"Tobin M. B.","year":"1994","journal-title":"FEMS Microbiol Lett"},{"key":"CIT0115","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0378-1119(95)00369-H","volume":"162","author":"Tobin M.B.","year":"1995","journal-title":"Gene"},{"key":"CIT0116","doi-asserted-by":"crossref","first-page":"5908","DOI":"10.1128\/jb.172.10.5908-5914.1990","volume":"172","author":"Tobin M. B.","year":"1990","journal-title":"J Bacteriol"},{"key":"CIT0117","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.chembiol.2007.01.012","volume":"14","author":"Ullan R. V.","year":"2007","journal-title":"Chem Biol"},{"key":"CIT0118","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1007\/s00438-004-1087-4","volume":"272","author":"Ullan R. V.","year":"2004","journal-title":"Mol Genet Genomics"},{"key":"CIT0119","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/nbt.1498","volume":"26","author":"van den Berg M. A.","year":"2008","journal-title":"Nat Biotechnol"},{"key":"CIT0120","first-page":"155","volume":"75","author":"van den Berg M. A.","year":"1999","journal-title":"Antonie Van Leeuwenhoek"},{"key":"CIT0121","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.fgb.2007.03.008","volume":"44","author":"van den Berg M. A.","year":"2007","journal-title":"Fungal Genet Biol"},{"key":"CIT0122","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1002\/(SICI)1097-0290(20000620)68:6<602::AID-BIT3>3.0.CO;2-2","volume":"68","author":"van Gulik W. M.","year":"2000","journal-title":"Biotechnol Bioeng"},{"key":"CIT0123","doi-asserted-by":"crossref","first-page":"3680","DOI":"10.1016\/S0021-9258(19)84905-0","volume":"264","author":"van Liempt H.","year":"1989","journal-title":"J Biol Chem"},{"key":"CIT0124","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1042\/BJ20061352","volume":"401","author":"Visser W. F.","year":"2007","journal-title":"Biochem J"},{"key":"CIT0125","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/0014-5793(93)81077-D","volume":"325","author":"Vollenbroich D.","year":"1993","journal-title":"FEBS Lett"},{"key":"CIT0126","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1128\/JB.51.6.753-759.1946","volume":"51","author":"Waksman S. A.","year":"1946","journal-title":"J Bacteriol"},{"key":"CIT0127","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/nrmicro727","volume":"1","author":"Walsh C.","year":"2003","journal-title":"Nat Rev Microbiol"},{"key":"CIT0128","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1021\/ar7000414","volume":"41","author":"Walsh C. T.","year":"2008","journal-title":"Acc Chem Res"},{"key":"CIT0129","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ymgme.2004.08.016","volume":"83","author":"Wanders R. J.","year":"2004","journal-title":"Mol Genet Metab"},{"key":"CIT0130","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.bbrc.2007.06.074","volume":"360","author":"Wang F. Q.","year":"2007","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0131","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1574-6968.2008.01294.x","volume":"287","author":"Wang F. Q.","year":"2008","journal-title":"FEMS Microbiol Lett)"},{"key":"CIT0132","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0969-2126(00)00120-9","volume":"8","author":"Weber T.","year":"2000","journal-title":"Structure"},{"key":"CIT0133","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1021\/jm00340a034","volume":"6","author":"Weinstein M. J.","year":"1963","journal-title":"J Med Chem"},{"key":"CIT0134","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/0014-5793(90)80224-7","volume":"262","author":"Whiteman P. A.","year":"1990","journal-title":"FEBS Lett"},{"key":"CIT0135","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0021-9673(00)00997-3","volume":"908","author":"Xie Y.","year":"2001","journal-title":"J Chromatogr A"},{"key":"CIT0136","doi-asserted-by":"crossref","first-page":"e50","DOI":"10.1093\/nar\/gni037","volume":"33","author":"Xu Z.","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"CIT0137","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1023\/A:1024595823747","volume":"25","author":"Yang L.","year":"2003","journal-title":"Biotechnol Lett"},{"key":"CIT0138","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/bit.10863","volume":"85","author":"Youshko M. I.","year":"2004","journal-title":"Biotechnol Bioeng"},{"key":"CIT0139","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1042\/bj2830691","volume":"283","author":"Zhang J.","year":"1992","journal-title":"Biochem J"}],"container-title":["Biotechnology and Genetic Engineering Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/02648725.2010.10648143","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,13]],"date-time":"2022-02-13T21:21:44Z","timestamp":1644787304000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/02648725.2010.10648143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":138,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["10.1080\/02648725.2010.10648143"],"URL":"https:\/\/doi.org\/10.1080\/02648725.2010.10648143","relation":{},"ISSN":["0264-8725","2046-5556"],"issn-type":[{"value":"0264-8725","type":"print"},{"value":"2046-5556","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1]]}}}