{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:24:00Z","timestamp":1777472640006,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2000,11]]},"abstract":"<jats:p>Purpose: To describe the MR findings in intramedullary tuberculomas and to discuss the usefulness of MR in the management of this pathology.<\/jats:p>\n                  <jats:p>Material and Methods: A retrospective study of 7 patients from 21 to 60 years of age with clinical and radiological evidence of intramedullary tuberculomas was undertaken. Both T1- and T2-weighted images (WI) were obtained along with postcontrast T1WI. Signal intensities (SIs) of the granulomas were compared with SIs of the normal spinal cord.<\/jats:p>\n                  <jats:p>Results: Six patients showed focus of tuberculosis elsewhere in the body. Six out of 7 showed fusiform swelling of the cord. Ill-defined iso-intensity (in 4 patients) to hyperintensity (in 3 patients) was seen at the site of granuloma on T1WI. On T2WI, 2 patients revealed a hypointense area (with disc enhancement). An iso-hypointense rim was seen surrounding a hyperintense centre in 5 patients (with rim enhancement). Adjacent oedema was seen in all patients. In 2 patients meningeal enhancement was also seen. In 2 patients the histopathology following surgical biopsy confirmed the diagnosis. In the remaining 5 patients, another known focus of tuberculosis elsewhere in the body and a marked response to antitubercular treatment was considered confirmatory for tuberculomas.<\/jats:p>\n                  <jats:p>Conclusion: Hypo- or iso-intensity on T2WI within the spinal cord with surrounding hyperintense oedema is suggestive of intramedullary tuberculomas. Central hyperintensities are also detected at times due to a variable amount of caseous necrosis with liquefaction. On T1WI, fusiform swelling of the cord is seen along with iso- to hyperintense foci, surrounded by hypointense oedema of the cord. Such findings should prompt a contrast-enhanced study, which may show single or conglomerate disc- or ring-enhancing lesions. MR thus plays an important role not only in detection and diagnosis, but also in deciding the treatment options and in the follow-up of those patients.<\/jats:p>","DOI":"10.1080\/028418500127345929","type":"journal-article","created":{"date-parts":[[2004,7,23]],"date-time":"2004-07-23T15:10:35Z","timestamp":1090595435000},"page":"572-577","source":"Crossref","is-referenced-by-count":32,"title":["Intramedullary tuberculomas: MR findings in seven patients"],"prefix":"10.1177","volume":"41","author":[{"given":"H.","family":"Parmar","sequence":"first","affiliation":[{"name":"Department of Radiology, King Edward VII Memorial Hospital, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of MRI, Dr. Balabhai Nanavati Hospital and Research Center, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Patkar","sequence":"additional","affiliation":[{"name":"Department of MRI, Dr. Balabhai Nanavati Hospital and Research Center, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Varma","sequence":"additional","affiliation":[{"name":"Department of Radiology, King Edward VII Memorial Hospital, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,8,30]]},"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/028418500127345929","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/028418500127345929","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:45:02Z","timestamp":1777383902000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1080\/028418500127345929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2000,11]]}},"alternative-id":["10.1080\/028418500127345929"],"URL":"https:\/\/doi.org\/10.1080\/028418500127345929","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,11]]}}}