{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:24:26Z","timestamp":1777472666840,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2000,11]]},"abstract":"<jats:p>Purpose: To determine the relationship between apparent diffusion coefficient (ADC) values measured by diffusion-weighted MR imaging and split renal function determined by renal scintigraphy in patients with hydronephrosis.<\/jats:p>\n                  <jats:p>\n                    Material and Methods: Diffusion-weighted imaging on a 1.5 T MR unit and renal scintigraphy were performed in 36 patients with hydronephrosis (45 hydronephrotic kidneys, 21 non-hydronephrotic kidneys). ADC values of the individual kidneys were measured by diffusion-weighted MR imaging. Split renal function (glomerular filtration rate (GFR)) was determined by renal scintigraphy using\n                    <jats:sup>99m<\/jats:sup>\n                    Tc-DTPA. The relationship between ADC values and split GFR was examined in 66 kidneys. The hydronephrotic kidneys were further classified into three groups (severe renal dysfunction, GFR &lt;10 ml\/min, n=7; moderate renal dysfunction, GFR 10-25 ml\/min, n=10; normal renal function, GFR &gt;25 ml\/min, n=28), and mean values for ADCs were calculated.\n                  <\/jats:p>\n                  <jats:p>\n                    Results: In hydronephrotic kidneys, there was a moderate positive correlation between ADC values and split GFR (R\n                    <jats:sup>2<\/jats:sup>\n                    =0.56). On the other hand, in non-hydronephrotic kidneys, poor correlation between ADC values and split GFR was observed (R\n                    <jats:sup>2<\/jats:sup>\n                    =0.08). The mean values for ADCs of the dysfunctioning hydronephrotic kidneys (severe renal dysfunction, 1.32\u00d710\n                    <jats:sup>-3<\/jats:sup>\n                    \u00b10.18\u00d710\n                    <jats:sup>-3<\/jats:sup>\n                    mm\n                    <jats:sup>2<\/jats:sup>\n                    \/s; moderate renal dysfunction, 1.38\u00d710\n                    <jats:sup>-3<\/jats:sup>\n                    \u00b10.10\u00d710\n                    <jats:sup>-3<\/jats:sup>\n                    mm\n                    <jats:sup>2<\/jats:sup>\n                    \/s) were significantly lower than that of the normal functioning hydronephrotic kidneys (1.63\u00d710\n                    <jats:sup>-3<\/jats:sup>\n                    \u00b10.12\u00b110\n                    <jats:sup>-3<\/jats:sup>\n                    mm\n                    <jats:sup>2<\/jats:sup>\n                    \/s).\n                  <\/jats:p>\n                  <jats:p>Conclusion: These results indicated that measurement of ADC values by diffusion-weighted MR imaging has a potential value in the evaluation of the functional status of hydronephrotic kidneys.<\/jats:p>","DOI":"10.1080\/028418500127346063","type":"journal-article","created":{"date-parts":[[2004,7,23]],"date-time":"2004-07-23T15:10:35Z","timestamp":1090595435000},"page":"642-646","source":"Crossref","is-referenced-by-count":37,"title":["Functional evaluation of hydronephrosis by diffusion-weighted MR imaging: Relationship between apparent diffusion coefficient and split glomerular filtration rate"],"prefix":"10.1177","volume":"41","author":[{"given":"S.","family":"Toyoshima","sequence":"first","affiliation":[{"name":"Department of Radiology, Toyama Medical and Pharmaceutical University, Toyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Noguchi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Toyama Medical and Pharmaceutical University, Toyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Seto","sequence":"additional","affiliation":[{"name":"Department of Radiology, Toyama Medical and Pharmaceutical University, Toyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Toyama Medical and Pharmaceutical University, Toyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Radiology, Toyama Medical and Pharmaceutical University, Toyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,8,30]]},"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/028418500127346063","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/028418500127346063","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:45:05Z","timestamp":1777383905000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1080\/028418500127346063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2000,11]]}},"alternative-id":["10.1080\/028418500127346063"],"URL":"https:\/\/doi.org\/10.1080\/028418500127346063","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,11]]}}}