{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:26:58Z","timestamp":1777472818339,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2001,9,1]],"date-time":"2001-09-01T00:00:00Z","timestamp":999302400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2001,9]]},"abstract":"<jats:p>Purpose: To evaluate the feasibility and efficacy of US-guided percutaneous ethanol injection (PEI) in the treatment of autonomous and toxic thyroid adenomas.<\/jats:p>\n                  <jats:p>\n                    Material and Methods: PEI was performed in 42 patients with solitary, scintigraphically \"hot\" nodules (n=37) or toxic nodular goiter (n=5). The nodular volume ranged from 2.5 to 38 cm\n                    <jats:sup>3<\/jats:sup>\n                    (mean volume, 20.7\u00b114.1 cm\n                    <jats:sup>3<\/jats:sup>\n                    ). Ethanol was injected using a free-hand technique, usually in multiple sessions, using color and power Doppler US guidance. Treatment success was evaluated following 3-4 months after PEI by scintigraphy, hormonal status, and US findings.\n                  <\/jats:p>\n                  <jats:p>Results: The procedure was technically successful in 39 patients (93%). Three patients were lost to follow-up. Minor complications were pain (all patients), subcutaneous hematoma (n=6), and transitory dysphonia (n=1). A complete cure was achieved in 22 patients (52%), and a partial cure in 10 patients (24%). In 4 cases (9%), the result was unsatisfactory since only moderate hormonal remission was observed. A satisfactory results was thus achieved in 32\/42 patients (76%). Significant nodular volume reduction was observed in all cases. Better results were observed in smaller nodules and in cases of autonomous adenomas. There were no cases of recurrent hyperthyreosis.<\/jats:p>\n                  <jats:p>Conclusion: US-guided PEI is an efficient and safe method in the treatment of autonomous thyroid nodules and it enables inactivation of nodules with minimal or transitory complications.<\/jats:p>","DOI":"10.1080\/028418501127347205","type":"journal-article","created":{"date-parts":[[2004,7,23]],"date-time":"2004-07-23T15:10:35Z","timestamp":1090595435000},"page":"477-481","source":"Crossref","is-referenced-by-count":19,"title":["Treatment of autonomous and toxic thyroid adenomas by percutaneous ultrasound-guided ethanol injection"],"prefix":"10.1177","volume":"42","author":[{"given":"B.","family":"Brkljacic","sequence":"first","affiliation":[{"name":"Department of Radiology, University Hospital \u201cMerkur\u201d, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sucic","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University Hospital \u201cDubrava\u201d, Zagreb, Croatia, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Bozikov","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University Hospital \u201cDubrava\u201d, Zagreb, Croatia, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hauser","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zurich University Hospital, Zurich, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Hebrang","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Hospital \u201cMerkur\u201d, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,8,30]]},"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/028418501127347205","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/028418501127347205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:45:26Z","timestamp":1777383926000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1080\/028418501127347205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,9]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,9]]}},"alternative-id":["10.1080\/028418501127347205"],"URL":"https:\/\/doi.org\/10.1080\/028418501127347205","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,9]]}}}