{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:36:00Z","timestamp":1777473360520,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T00:00:00Z","timestamp":1112313600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:p>Purpose: To analyze the metacarpophalangeal profile (MCPP) in individuals with Leri\u2010Weill dyschondrosteosis (LWD) and to assess its value as a possible contributor to early diagnosis.<\/jats:p>\n                  <jats:p>Material and Methods: Hand profiles of 39 individuals with a diagnosis of LWD were calculated and analyzed. Discriminant analysis was applied to differentiate between LWD and normal individuals.<\/jats:p>\n                  <jats:p>Results: There was a distinct pattern profile in LWD. Mean pattern profile showed two bone\u2010shortening gradients, with increasing shortening from distal to proximal and from medial to lateral. Distal phalanx 2 was disproportionately long and second metacarpal was disproportionately short. Discriminant analysis yielded correct classification in 72% of analyzed cases.<\/jats:p>\n                  <jats:p>Conclusion: MCPP is not age\u2010related and the analysis can be applied at any age, facilitating early diagnosis of LWD. In view of its availability, low costs, and diagnostic value, MCPP analysis should be considered as a routine method in the patients of short stature where LWD is suspected.<\/jats:p>","DOI":"10.1080\/02841850510020978","type":"journal-article","created":{"date-parts":[[2009,12,9]],"date-time":"2009-12-09T07:33:50Z","timestamp":1260344030000},"page":"200-207","source":"Crossref","is-referenced-by-count":2,"title":["Metacarpophalangeal pattern profile analysis in leri\u2010weill dyschondrosteosis"],"prefix":"10.1177","volume":"46","author":[{"given":"E.","family":"Laurencikas","sequence":"first","affiliation":[{"name":"Department of Pediatric Radiology, Department of Pediatric Endocrinology, and Department of Social Medicine, Karolinska Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"S\u00f6derman","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Department of Pediatric Endocrinology, and Department of Social Medicine, Karolinska Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Grigelioniene","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Department of Pediatric Endocrinology, and Department of Social Medicine, Karolinska Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Hagen\u00e4s","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Department of Pediatric Endocrinology, and Department of Social Medicine, Karolinska Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Jorulf","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Department of Pediatric Endocrinology, and Department of Social Medicine, Karolinska Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,8,30]]},"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/02841850510020978","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/02841850510020978","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:46:40Z","timestamp":1777384000000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1080\/02841850510020978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["10.1080\/02841850510020978"],"URL":"https:\/\/doi.org\/10.1080\/02841850510020978","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,4]]}}}