{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:58:09Z","timestamp":1777474689904,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:p>Purpose: To evaluate the influence of a second radioisotope injection on the intraoperative success rate in patients with non-visualized axillary sentinel nodes (SN).<\/jats:p>\n                  <jats:p>\n                    Material and Methods: Altogether, 534 consecutive breast cancer patients with lymphoscintigraphy (LS) and SN biopsy and were included. An intratumoral injection of\n                    <jats:sup>99m<\/jats:sup>\n                    Tc-labeled human albumin colloid with a median dose of 93 MBq was applied. Forty-two of the 80 patients without axillary hot spots on LS received a second tracer injection with a median dose of 70 MBq.\n                  <\/jats:p>\n                  <jats:p>Results: The visualization rate of axillary SN was 454\/534 (85%). The intraoperative SN identification rate was 97% in patients with and 69% in patients without visualized SN in the axilla ( P&lt;0.00005), but the success rate was higher (88%) with a second radioisotope injection than without it (47%; P&lt;0.0002).<\/jats:p>\n                  <jats:p>Conclusion: The failure rate in intraoperative SN identification was minimized using a second radioisotope injection in patients without axillary SN on LS.<\/jats:p>","DOI":"10.1080\/02841850600830654","type":"journal-article","created":{"date-parts":[[2006,10,2]],"date-time":"2006-10-02T14:17:34Z","timestamp":1159798654000},"page":"760-763","source":"Crossref","is-referenced-by-count":9,"title":["A second radioisotope injection enhances intraoperative sentinel node identification in breast cancer patients without visualized nodes on preoperative lymphoscintigraphy"],"prefix":"10.1177","volume":"47","author":[{"given":"J. P.","family":"Leikola","sequence":"first","affiliation":[{"name":"Breast Surgery Unit, Maria Hospital, Helsinki, Finland; Department of Nuclear Medicine, Helsinki University Hospital, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. A.","family":"Lepp\u00e4nen","sequence":"additional","affiliation":[{"name":"Breast Surgery Unit, Maria Hospital, Helsinki, Finland; Department of Nuclear Medicine, Helsinki University Hospital, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. A. J.","family":"von Smitten","sequence":"additional","affiliation":[{"name":"Breast Surgery Unit, Maria Hospital, Helsinki, Finland; Department of Nuclear Medicine, Helsinki University Hospital, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. H. K.","family":"Leidenius","sequence":"additional","affiliation":[{"name":"Breast Surgery Unit, Maria Hospital, Helsinki, Finland; Department of Nuclear Medicine, Helsinki University Hospital, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,8,30]]},"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/02841850600830654","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/02841850600830654","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:49:56Z","timestamp":1777384196000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1080\/02841850600830654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["10.1080\/02841850600830654"],"URL":"https:\/\/doi.org\/10.1080\/02841850600830654","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10]]}}}