{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:54:38Z","timestamp":1777474478342,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:p>Purpose: To evaluate the role of cardiac sympathetic innervation in patients whose clinical features consisted of chest pain, transient ST-segment elevation, left ventricular apical akinesis, minimal elevation of cardiac enzymes, and onset of symptoms shortly after a severe stress condition.<\/jats:p>\n                  <jats:p>\n                    Material and Methods: Five female patients, mean age 67\u00b114 years, underwent thoracic\n                    <jats:sup>123<\/jats:sup>\n                    I-MIBG (planar and SPECT) and\n                    <jats:sup>67<\/jats:sup>\n                    Ga citrate (planar) scans within 5 days after the onset of symptoms. The\n                    <jats:sup>123<\/jats:sup>\n                    I-MIBG myocardial washout rate between early (30\u2005min) and delayed (3\u2005hours) planar images was calculated. All patients presented findings consistent with takotsubo-like syndrome. Echocardiograms showed the characteristic wall motion pattern of significant apical dysfunction. Acute-phase coronary angiographies revealed a non-obstructive pattern. A peculiar apical akinesis and basal normokinesis were observed on the ventriculograms.\n                  <\/jats:p>\n                  <jats:p>\n                    Results: Impairment of cardiac neuronal uptake of\n                    <jats:sup>123<\/jats:sup>\n                    I-MIBG based on a reduction of the heart-to-mediastinum uptake ratio was observed in all patients, while the washout rate was raised in four patients. All patients presented an apical uptake defect in the\n                    <jats:sup>123<\/jats:sup>\n                    I-MIBG SPECT and planar images and a normal\n                    <jats:sup>67<\/jats:sup>\n                    Ga scintigraphy.\n                  <\/jats:p>\n                  <jats:p>\n                    Conclusion: Our data indicate that ampulla cardiomyopathy (AC) is associated with a cardiac sympathetic innervation deficit characterized by a reduced global\n                    <jats:sup>123<\/jats:sup>\n                    I-MIBG uptake and an apical uptake defect. The lack of\n                    <jats:sup>67<\/jats:sup>\n                    Ga uptake in the acute phase of this syndrome indicates that AC is probably not associated with an inflammatory process.\n                  <\/jats:p>","DOI":"10.1080\/02841850600928482","type":"journal-article","created":{"date-parts":[[2006,11,29]],"date-time":"2006-11-29T19:45:08Z","timestamp":1164829508000},"page":"1029-1035","source":"Crossref","is-referenced-by-count":20,"title":["Assessment of takotsubo (ampulla) cardiomyopathy using iodine-123 metaiodobenzylguanidine scintigraphy"],"prefix":"10.1177","volume":"47","author":[{"given":"Pinheiro M. C.","family":"Pessoa","sequence":"first","affiliation":[{"name":"Departamento de Radiologia, Faculdade de Medicina, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Pro-Echo\/Hospital Samaritano, Servi\u00e7o de Medicina Nuclear, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salles S.","family":"Xavier","sequence":"additional","affiliation":[{"name":"Departamento de Radiologia, Faculdade de Medicina, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Pro-Echo\/Hospital Samaritano, Servi\u00e7o de Medicina Nuclear, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Souza Le\u00e3o R.","family":"Lima","sequence":"additional","affiliation":[{"name":"Departamento de Radiologia, Faculdade de Medicina, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Pro-Echo\/Hospital Samaritano, Servi\u00e7o de Medicina Nuclear, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Mansur","sequence":"additional","affiliation":[{"name":"Departamento de Radiologia, Faculdade de Medicina, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Pro-Echo\/Hospital Samaritano, Servi\u00e7o de Medicina Nuclear, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Altino S.","family":"de Almeida","sequence":"additional","affiliation":[{"name":"Departamento de Radiologia, Faculdade de Medicina, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Pro-Echo\/Hospital Samaritano, Servi\u00e7o de Medicina Nuclear, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pires A. C.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Departamento de Radiologia, Faculdade de Medicina, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Pro-Echo\/Hospital Samaritano, Servi\u00e7o de Medicina Nuclear, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Gutfilen","sequence":"additional","affiliation":[{"name":"Departamento de Radiologia, Faculdade de Medicina, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Pro-Echo\/Hospital Samaritano, Servi\u00e7o de Medicina Nuclear, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbosa L. M.","family":"da Fonseca","sequence":"additional","affiliation":[{"name":"Departamento de Radiologia, Faculdade de Medicina, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Pro-Echo\/Hospital Samaritano, Servi\u00e7o de Medicina Nuclear, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,8,30]]},"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/02841850600928482","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/02841850600928482","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:49:24Z","timestamp":1777384164000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1080\/02841850600928482"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1080\/02841850600928482"],"URL":"https:\/\/doi.org\/10.1080\/02841850600928482","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,12]]}}}