{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:43:00Z","timestamp":1768398180485,"version":"3.49.0"},"reference-count":28,"publisher":"MJS Publishing, Medical Journals Sweden AB","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Oncologica"],"published-print":{"date-parts":[[2000,1]]},"DOI":"10.1080\/02841860050215927","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T12:02:27Z","timestamp":1027684947000},"page":"941-947","source":"Crossref","is-referenced-by-count":46,"title":["Morphine or Oxycodone in Cancer Pain?"],"prefix":"10.2340","volume":"39","author":[{"family":"Tarja E. Heiskanen, P\u00e4ivi M. Ruism\u00e4","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1183","published-online":{"date-parts":[[2009,7,8]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1056\/NEJM199610103351507","volume":"335","author":"Levy MH","year":"1996","journal-title":"N Engl J Med"},{"key":"CIT0002","first-page":"378","volume":"10","author":"de Stoutz ND","year":"1995","journal-title":"Opioid rotation for toxicity reduction in terminal cancer patients. J Pain Symptom Manage"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0304-3959(96)03286-1","volume":"70","author":"Ripamonti C","year":"1997","journal-title":"Pain"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0304-3959(97)00072-9","volume":"73","author":"Heiskanen T","year":"1997","journal-title":"Pain"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/j.1399-6576.1991.tb03364.x","volume":"35","author":"Kalso E","year":"1991","journal-title":"Acta Anaesthesiol Scand"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/clpt.1990.85","volume":"47","author":"Kalso E","year":"1990","journal-title":"Clin Pharmacol Ther"},{"key":"CIT0007","first-page":"401","volume":"53","author":"Otton SW","year":"1993","journal-title":"Inhibi-tion by iluoxetine of cytochrome P450 2D6 activity. Clin Pharmacol Ther"},{"key":"CIT0008","first-page":"102","volume":"17","author":"Price Evans DA","year":"1980","journal-title":"A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population. J Med Genet"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S0009-9236(96)90024-7","volume":"59","author":"Kaiko R","year":"1996","journal-title":"Clin Pharmacol Ther"},{"key":"CIT0010","first-page":"773","volume":"36","author":"Wedlund PJ","year":"1984","journal-title":"Branch RA. Mephenytoin hydroxylation deficiency in Cau-casians: frequency of a new oxidative drug metabolism poly-morphism. Clin Pharmacol Ther"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1002\/jps.2600680441","volume":"68","author":"Weinstein SC","year":"1979","journal-title":"J Pharmacol Sci"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/j.1365-2125.1992.tb04090.x","volume":"33","author":"P\u00f6yhi\u00e4 R","year":"1992","journal-title":"Br J Clin Pharmacol"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S0378-4347(00)83707-X","volume":"375","author":"Svensson JO","year":"1986","journal-title":"J Chromatogr"},{"key":"CIT0014","first-page":"840","volume":"42","author":"Hanks GW","year":"1987","journal-title":"Bliss JM. Controlled-release mor-phine tablets: a double-blind trial in patients with advanced cancer. Anaesthesia"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1990.145"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0304-3959(97)00142-5","volume":"74","author":"Faura CC","year":"1998","journal-title":"Pain"},{"key":"CIT0017","first-page":"247","volume":"13","author":"Neumann PB","year":"1982","journal-title":"Plasma mor-phine concentrations during chronic oral administration in patients with cancer pain. Pain"},{"key":"CIT0018","first-page":"601","volume":"60","author":"Hellriegel ET","year":"1996","journal-title":"Hauck WW. Interpatient vari-ability in bioavailability is related to the extent of absorption: implications for bioavailability and bioequivalence studies. Clin Pharmacol Ther"},{"key":"CIT0019","first-page":"147","volume":"62","author":"Wolff T","year":"1995","journal-title":"Morphine and morphine metabolite concentrations in cerebrospinal fluid and plasma in cancer pain patients after slow-release oral morphine adminis-tration. Pain"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1093\/bja\/56.8.821","volume":"58","author":"Vater M","year":"1984","journal-title":"Br J Anaesth"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1046\/j.1365-2125.1996.32810.x","volume":"41","author":"Drake J","year":"1996","journal-title":"Br J Clin Pharmacol"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/clpt.1992.176","volume":"52","author":"Leow KP","year":"1992","journal-title":"ain Pharmacol Ther"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"12 \u2014 9","DOI":"10.1038\/clpt.1990.2","volume":"47","author":"Osborne R","year":"1990","journal-title":"Clin Pharmacol Ther"},{"key":"CIT0024","first-page":"101","volume":"207","author":"Beaver WT","year":"1978","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0025","first-page":"655","volume":"61","author":"Tallgren M","year":"1997","journal-title":"Pharmacokinetics of oxycodone before and after liver transplantation. Clin Pharmacol Ther"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1093\/bja\/79.6.804","volume":"79","author":"Kotb HIM","year":"1997","journal-title":"Br J Anaesth"},{"key":"CIT0027","first-page":"13","volume":"8","author":"Kirveld M","year":"1996","journal-title":"The pharma-cokinetics of oxycodone in uremic patients undergoing renal transplantation. J ain Anesth"},{"key":"CIT0028","first-page":"158","volume":"54","author":"Osborne R","year":"1993","journal-title":"The pharmacokinetics of morphine and morphine glucuronides in kidney failure. ain Pharmacol Ther"}],"container-title":["Acta Oncologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/02841860050215927","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T18:02:55Z","timestamp":1756404175000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicaljournalssweden.se\/actaoncologica\/article\/view\/26122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":28,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2009,7,8]]},"published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.1080\/02841860050215927"],"URL":"https:\/\/doi.org\/10.1080\/02841860050215927","relation":{},"ISSN":["0284-186X","1651-226X"],"issn-type":[{"value":"0284-186X","type":"print"},{"value":"1651-226X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,1]]}}}