{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:47:40Z","timestamp":1788306460611,"version":"build-2803163510"},"reference-count":28,"publisher":"Informa UK Limited","issue":"4","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Current Medical Research and Opinion"],"published-print":{"date-parts":[[2018,4,3]]},"DOI":"10.1080\/03007995.2017.1407302","type":"journal-article","created":{"date-parts":[[2017,11,18]],"date-time":"2017-11-18T00:08:24Z","timestamp":1510963704000},"page":"577-583","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":6,"title":["Observational cohort study: safety outcomes in children using proton pump inhibitors or histamine-2 receptor antagonists"],"prefix":"10.1080","volume":"34","author":[{"given":"Eline","family":"Houben","sequence":"first","affiliation":[{"name":"PHARMO Institute for Drug Outcomes Research, Utrecht, Netherlands;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saga","family":"Johansson","sequence":"additional","affiliation":[{"name":"Global Medical Affairs, Medical Evidence and Observational Research Centre, AstraZeneca Gothenburg, M\u00f6lndal, Sweden (at the time of the study);"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Nagy","sequence":"additional","affiliation":[{"name":"AstraZeneca Gothenburg, M\u00f6lndal, Sweden (at the time of the study);"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernie J. A.","family":"Penning-van Beest","sequence":"additional","affiliation":[{"name":"PHARMO Institute for Drug Outcomes Research, Utrecht, Netherlands;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0633-3098","authenticated-orcid":false,"given":"Ernst J.","family":"Kuipers","sequence":"additional","affiliation":[{"name":",","place":["Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron M. C.","family":"Herings","sequence":"additional","affiliation":[{"name":"PHARMO Institute for Drug Outcomes Research, Utrecht, Netherlands;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2017,11,24]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365520903428606"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.2165\/00148581-200911030-00004"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181b7f563"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.129"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000076370"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.2165\/00148581-200810030-00008"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-0421"},{"key":"e_1_3_3_9_1","unstructured":"National Institute for Health and Care Excellence. Gastro-oesophageal reflux disease: recognition diagnosis and management in children and young people. NICE Guideline 1: methods evidence and recommendations. 2015. Available at: https:\/\/www.ncbi.nlm.nih.gov\/pubmedhealth\/PMH0076656\/pdf\/PubMedHealth_PMH0076656.pdf [Last accessed 1 February 2017]"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2013.199"},{"key":"e_1_3_3_11_1","unstructured":"Kinderformularium. Esomeprazol. Available at: https:\/\/www.kinderformularium.nl\/geneesmiddel\/521\/esomeprazol [Last accessed 27 February 2017]"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(13)61436-5"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2012.11.031"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1299"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000000815"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12619"},{"key":"e_1_3_3_17_1","first-page":"CD008550","article-title":"Pharmacological treatment of children with gastro-oesophageal reflux","volume":"11","author":"Tighe M","year":"2014","unstructured":"Tighe M, Afzal NA, Bevan A, et\u00a0al. Pharmacological treatment of children with gastro-oesophageal reflux. Cochrane Database Syst Rev 2014;11:CD008550","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119959946.ch18"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2009.09.010"},{"key":"e_1_3_3_20_1","unstructured":"Foundation DHD. Dutch Hospital Data. Available at: www.dutchhospitaldata.nl [Last accessed 4 September 2017]"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.2147\/AHMT.S23193"},{"key":"e_1_3_3_22_1","unstructured":"Farmacotherapeutisch Kompas. 2011. Available at: https:\/\/www.farmacotherapeutischkompas.nl\/ [Last accessed 2 February 2017]"},{"key":"e_1_3_3_23_1","unstructured":"Nederlandse Vereniging voor Kindergeneeskunde. Richtlijn: Gastro-oesofageale reflux(ziekte) bij kinderen van 0-18 jaar. 2012. Available at: https:\/\/www.nvk.nl\/Kwaliteit\/Richtlijnenoverzicht\/Details\/tabid\/1558\/articleType\/ArticleView\/articleId\/630\/Gastro-oesofageale-refluxziekte-bij-kinderen-van-0-18-jaar.aspx#tab12 [Last accessed 27 February 2017]"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1586\/ecp.12.20"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13304"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i5813"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2016.06.039"},{"key":"e_1_3_3_28_1","first-page":"253","article-title":"Post-marketing surveillance of the safety of cimetidine: twelve-month morbidity report","volume":"54","author":"Colin Jones DG","year":"1985","unstructured":"Colin Jones DG, Langman MJ, Lawson DH, et\u00a0al. Post-marketing surveillance of the safety of cimetidine: twelve-month morbidity report. Q J Med 1985;54:253-68","journal-title":"Q J Med"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200326020-00005"}],"container-title":["Current Medical Research and Opinion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/03007995.2017.1407302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T14:45:47Z","timestamp":1770389147000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/03007995.2017.1407302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,24]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4,3]]}},"alternative-id":["10.1080\/03007995.2017.1407302"],"URL":"https:\/\/doi.org\/10.1080\/03007995.2017.1407302","relation":{},"ISSN":["0300-7995","1473-4877"],"issn-type":[{"value":"0300-7995","type":"print"},{"value":"1473-4877","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,24]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=icmo20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=icmo20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2017-10-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-11-15","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-11-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-11-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}