{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:59Z","timestamp":1787702459139,"version":"build-2784847793"},"reference-count":35,"publisher":"Informa UK Limited","issue":"6","license":[{"start":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T00:00:00Z","timestamp":1748908800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Current Medical Research and Opinion"],"published-print":{"date-parts":[[2025,6,3]]},"DOI":"10.1080\/03007995.2025.2515280","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T04:21:40Z","timestamp":1750220500000},"page":"1097-1109","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["Real-world clinical outcomes of patients with moderate-to-severe rheumatoid arthritis initiating upadacitinib in the United Kingdom: final analysis from a prospective observational cohort study (ENDEAVOUR)"],"prefix":"10.1080","volume":"41","author":[{"given":"James","family":"Taylor","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Northampton General Hospital","place":["Northampton, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinivasan","family":"Srirangan","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Medway Maritime Hospital","place":["Gillingham, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwan","family":"Bukhari","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, University Hospitals of Morecambe Bay NHS Foundation Trust","place":["Lancaster, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed","family":"Bilgrami","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, University Hospitals of Morecambe Bay NHS Foundation Trust","place":["Lancaster, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad K.","family":"Nisar","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Luton & Dunstable Hospital","place":["Luton, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"McDonald","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Altnagelvin Area Hospital, Western Health and Social Care Trust","place":["Londonderry, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Goodson","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Liverpool University Hospitals NHS Foundation Trust","place":["Liverpool, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Allard","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Royal United Hospitals Bath NHS Foundation Trust","place":["Bath, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Kinder","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, University Hospitals Leicester","place":["Leicester, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, York & Scarborough Teaching Hospitals NHS Foundation Trust","place":["York, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Hunt","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, York & Scarborough Teaching Hospitals NHS Foundation Trust","place":["York, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Raizada","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Royal Wolverhampton Hospital","place":["Wolverhampton, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Kirkham","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Guy\u2019s & St Thomas Hospital","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleri","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Royal Gwent Hospital, Aneurin Bevan University Health Board","place":["Newport, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Horsfall","sequence":"additional","affiliation":[{"name":"Medical Department, AbbVie Ltd","place":["Maidenhead, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terri-Leigh","family":"Niblock","sequence":"additional","affiliation":[{"name":"Medical Department, AbbVie Ltd","place":["Maidenhead, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Burton","sequence":"additional","affiliation":[{"name":"Medical Department, AbbVie Ltd","place":["Maidenhead, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Galloway","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, King\u2019s College London","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,6,30]]},"reference":[{"key":"e_1_3_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(23)01525-8"},{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-015-3415-x"},{"key":"e_1_3_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-207524"},{"key":"e_1_3_6_5_1","unstructured":"National Institute for Health and Care Excellence. Upadacitinib for treating moderate rheumatoid arthritis. Available from: www.nice.org.uk\/guidance\/ta744. London: National Institute for Health and Care Excellence; 2021."},{"key":"e_1_3_6_6_1","unstructured":"National Institute for Health and Care Excellence. Upadacitinib for treating severe rheumatoid arthritis. Available from: www.nice.org.uk\/guidance\/ta665. London: National Institute for Health and Care Excellence; 2020."},{"key":"e_1_3_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2009.10.001"},{"key":"e_1_3_6_8_1","unstructured":"National Institute for Health and Care Excellence. Rheumatoid arthritis in adults: management NICE guideline [NG100]. Available from: 2020https:\/\/www.nice.org.uk\/guidance\/ng100."},{"key":"e_1_3_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab464"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-208669"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41927-020-00161-4"},{"key":"e_1_3_6_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41927-019-0054-y"},{"key":"e_1_3_6_13_1","unstructured":"NHS England. ; 2022 Implementing patient-initiated follow-up (PIFU) in adult rheumatology services."},{"key":"e_1_3_6_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41927-020-00143-6"},{"key":"e_1_3_6_15_1","volume-title":"Getting it right first time","author":"Kay L","year":"2021","unstructured":"Kay L, Lanyon P, MacGregor A. Getting it right first time. Rheumatology: GIRFT Programme National Specialty Report; 2021."},{"key":"e_1_3_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(18)31115-2"},{"key":"e_1_3_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(18)31116-4"},{"key":"e_1_3_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(19)30419-2"},{"key":"e_1_3_6_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2019-215764"},{"key":"e_1_3_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41384"},{"key":"e_1_3_6_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2008250"},{"key":"e_1_3_6_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kes279"},{"key":"e_1_3_6_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41032"},{"key":"e_1_3_6_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-006560"},{"key":"e_1_3_6_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab078"},{"key":"e_1_3_6_26_1","doi-asserted-by":"publisher","DOI":"10.2147\/ceor.S183076"},{"key":"e_1_3_6_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.092734"},{"key":"e_1_3_6_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa027"},{"key":"e_1_3_6_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.143586"},{"key":"e_1_3_6_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40744-019-0164-4"},{"key":"e_1_3_6_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq109"},{"key":"e_1_3_6_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2024-eular.2238"},{"key":"e_1_3_6_33_1","doi-asserted-by":"publisher","DOI":"10.55563\/clinexprheumatol\/11255h"},{"key":"e_1_3_6_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40744-024-00651-8"},{"key":"e_1_3_6_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e8668"},{"key":"e_1_3_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2020.11.005"}],"container-title":["Current Medical Research and Opinion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/03007995.2025.2515280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T16:52:39Z","timestamp":1754412759000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/03007995.2025.2515280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,3]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6,3]]}},"alternative-id":["10.1080\/03007995.2025.2515280"],"URL":"https:\/\/doi.org\/10.1080\/03007995.2025.2515280","relation":{},"ISSN":["0300-7995","1473-4877"],"issn-type":[{"value":"0300-7995","type":"print"},{"value":"1473-4877","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,3]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=icmo20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=icmo20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-02-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-19","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}