{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:48:06Z","timestamp":1792075686224,"version":"4.4.0"},"reference-count":86,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Current Medical Research and Opinion"],"DOI":"10.1080\/03007995.2026.2741495","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:39:55Z","timestamp":1792075195000},"page":"1-14","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["Advances in disease management and treatment outcomes for obesity and knee osteoarthritis in primary care practice"],"prefix":"10.1080","author":[{"given":"Amanda E.","family":"Nelson","sequence":"first","affiliation":[{"name":"Thurston Arthritis Research Center, University of North Carolina at Chapel Hill","place":["Chapel Hill, USA"]},{"name":"Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina","place":["Chapel Hill, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leigh F.","family":"Callahan","sequence":"additional","affiliation":[{"name":"Thurston Arthritis Research Center, University of North Carolina at Chapel Hill","place":["Chapel Hill, USA"]},{"name":"Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina","place":["Chapel Hill, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Schnitzer","sequence":"additional","affiliation":[{"name":"Departments of Physical Medicine and Rehabilitation, Anesthesiology and Internal Medicine\/Rheumatology, Northwestern University Feinberg School of Medicine","place":["Chicago, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Batsis","sequence":"additional","affiliation":[{"name":"Thurston Arthritis Research Center, University of North Carolina at Chapel Hill","place":["Chapel Hill, USA"]},{"name":"Division of Geriatric Medicine, School of Medicine, Department of Nutrition, The Gillings School of Global Public Health","place":["Chapel Hill, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.22171"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)02322-5"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.63032\/SDVB2224"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12173"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41142"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2023.10.008"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2023.06.011"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1676107"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2023-225041"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2019.06.011"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2019.04.008"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eprac.2025.07.017"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22891"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2021.1982588"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638280701774233"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.3310\/pgfar06040"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(23)00163-7"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2025.1561750"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2021.05.007"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21898"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines13071644"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.OA.25.00192"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-019-2895-3"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5868-5-4"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-025-08432-2"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2010.11.010"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2011.03.006"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines12061262"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.10.011"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocarto.2024.100511"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.277669"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24765"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.210543"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.21893"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2023-107793"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.70025"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2024.08.012"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.2023-0819"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.31138\/mjr.121224.wlc"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-021-01710-0"},{"key":"e_1_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1148209"},{"key":"e_1_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2022.106320"},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.70164"},{"key":"e_1_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.13230"},{"key":"e_1_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2024.1431292"},{"key":"e_1_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2020.02.006"},{"key":"e_1_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2032183"},{"key":"e_1_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.1831"},{"key":"e_1_3_3_50_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2206038"},{"key":"e_1_3_3_51_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.3224"},{"key":"e_1_3_3_52_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411892"},{"key":"e_1_3_3_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14725"},{"key":"e_1_3_3_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13679-023-00534-z"},{"key":"e_1_3_3_55_1","unstructured":"OARSI. OA as a Serious Disease. [cited 2026 Oct 6]; Available from: https:\/\/oarsi.org\/research-oarsi-success\/oa-serious-disease."},{"key":"e_1_3_3_56_1","doi-asserted-by":"publisher","DOI":"10.32948\/ajpt.2024.11.22"},{"key":"e_1_3_3_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01643-X"},{"key":"e_1_3_3_58_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2306963"},{"key":"e_1_3_3_59_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2313917"},{"key":"e_1_3_3_60_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2403664"},{"key":"e_1_3_3_61_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqaa328"},{"key":"e_1_3_3_62_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2023-223845"},{"key":"e_1_3_3_63_1","doi-asserted-by":"publisher","DOI":"10.1177\/23259671241297157"},{"key":"e_1_3_3_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000041243"},{"key":"e_1_3_3_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.70209"},{"key":"e_1_3_3_66_1","volume-title":"WEGOVY (semaglutide) injection, for subcutaneous use [package insert]","author":"WEGOVY","year":"2024","unstructured":"WEGOVY. WEGOVY (semaglutide) injection, for subcutaneous use [package insert]. Plainsboro (NJ): Novo Nordisk Inc.; 2024."},{"key":"e_1_3_3_67_1","volume-title":"ZEPBOUND-tirzepatide injection, solution [package insert]","author":"ZEPBOUND","year":"2024","unstructured":"ZEPBOUND. ZEPBOUND-tirzepatide injection, solution [package insert]. Indianapolis (IN): Eli Lilly and Company; 2024."},{"key":"e_1_3_3_68_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.24290"},{"key":"e_1_3_3_69_1","doi-asserted-by":"publisher","DOI":"10.2147\/DMSO.S447582"},{"key":"e_1_3_3_70_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14155434"},{"key":"e_1_3_3_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(25)00027-0"},{"key":"e_1_3_3_72_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S555622"},{"key":"e_1_3_3_73_1","doi-asserted-by":"publisher","DOI":"10.7326\/ANNALS-24-03609"},{"key":"e_1_3_3_74_1","doi-asserted-by":"publisher","DOI":"10.1177\/20420188261472587"},{"key":"e_1_3_3_75_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.15473"},{"key":"e_1_3_3_76_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.27850"},{"key":"e_1_3_3_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13679-021-00441-1"},{"key":"e_1_3_3_78_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu18081213"},{"key":"e_1_3_3_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12264"},{"key":"e_1_3_3_80_1","doi-asserted-by":"publisher","DOI":"10.1097\/CORR.0000000000000784"},{"key":"e_1_3_3_81_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40795-021-00480-w"},{"key":"e_1_3_3_82_1","doi-asserted-by":"publisher","DOI":"10.1159\/000528083"},{"key":"e_1_3_3_83_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6717a2"},{"key":"e_1_3_3_84_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0266217"},{"key":"e_1_3_3_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-020-00523-9"},{"key":"e_1_3_3_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-014-3031-6"},{"key":"e_1_3_3_87_1","unstructured":"Osteoarthritis Action Alliance. Arthritis-Appropriate Evidence-Based Interventions (AAEBI). [cited 2026 Oct 6]; Available from: https:\/\/oaaction.unc.edu\/aaebi-2\/."}],"container-title":["Current Medical Research and Opinion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/03007995.2026.2741495","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/03007995.2026.2741495","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/03007995.2026.2741495","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:39:57Z","timestamp":1792075197000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/03007995.2026.2741495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,15]]},"references-count":86,"alternative-id":["10.1080\/03007995.2026.2741495"],"URL":"https:\/\/doi.org\/10.1080\/03007995.2026.2741495","relation":{},"ISSN":["0300-7995","1473-4877"],"issn-type":[{"value":"0300-7995","type":"print"},{"value":"1473-4877","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,15]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=icmo20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=icmo20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2026-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-24","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}