{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T20:22:25Z","timestamp":1771014145956,"version":"3.50.1"},"reference-count":89,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scandinavian Journal of Rheumatology"],"published-print":{"date-parts":[[2004,12,31]]},"DOI":"10.1080\/03009740410010290","type":"journal-article","created":{"date-parts":[[2004,11,29]],"date-time":"2004-11-29T12:20:17Z","timestamp":1101730817000},"page":"365-372","source":"Crossref","is-referenced-by-count":39,"title":["The systemic nature of the antiphospholipid syndrome"],"prefix":"10.1080","volume":"33","author":[{"given":"I","family":"Marai","sequence":"first","affiliation":[{"name":"Department of Internal Medicine 'B' and Centre for Autoimmune Diseases, Sheba Medical Centre, Tel-Hashomer; Sackler Faculty of Medicine Tel-Aviv University Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Zandman-Goddard","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine 'B' and Centre for Autoimmune Diseases, Sheba Medical Centre, Tel-Hashomer; Sackler Faculty of Medicine Tel-Aviv University Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Shoenfeld","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine 'B' and Centre for Autoimmune Diseases, Sheba Medical Centre, Tel-Hashomer; Sackler Faculty of Medicine Tel-Aviv University Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1191\/0961203303lu396xx"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.287.6399.1088"},{"key":"e_1_2_1_4_1","first-page":"366","article-title":"Ordi-Ros J, Derksen RH, Machin SJ, Barquinero J, et al","volume":"68","author":"Asherson RA","year":"1989","unstructured":"Asherson RA, Khamashta MA, Ordi-Ros J, Derksen RH, Machin SJ, Barquinero J, et al. The 'primary' antiphos-pholipid syndrome: major clinical and serological features. Medicine (Baltimore) 1989;68:366\u201374.","journal-title":"The 'primary' antiphos-pholipid syndrome: major clinical and serological features. Medicine (Baltimore)"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra002974"},{"key":"e_1_2_1_6_1","first-page":"495","article-title":"Following 90 patients with antiphospholipid syndrome with antibody titers and correlations with clinical manifestations: symptoms of the disease, a new antibody and correlations with clinical mani-festations in the Israeli population","volume":"140","author":"Marai I","year":"2001","unstructured":"Marai I, Levi Y, Godard G, Shoenfeld Y. Following 90 patients with antiphospholipid syndrome with antibody titers and correlations with clinical manifestations: symptoms of the disease, a new antibody and correlations with clinical mani-festations in the Israeli population. Harefuah 2001;140: 495\u2013500.","journal-title":"Harefuah"},{"key":"e_1_2_1_7_1","first-page":"309","article-title":"Zandeman-Goddard G, Blank M, Lorber M, Lorber A, et al","volume":"4","author":"Adler Y","year":"1995","unstructured":"Adler Y, Finkelstein Y, Zandeman-Goddard G, Blank M, Lorber M, Lorber A, et al. The presence of antiphospholipid antibodies in acute myocardial infarction. Lupus 1995;4: 309\u201313.","journal-title":"The presence of antiphospholipid antibodies in acute myocardial infarction. Lupus"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1385\/CRIAI:23:3:341"},{"key":"#cr-split#-e_1_2_1_9_1.1","doi-asserted-by":"crossref","unstructured":"Brey RL Chapman J Levine SR Ruiz-Irastorza G Derksen RH Khamashta M et al. Stroke and the antiphos-pholipid syndrome: consensus meeting Taoromina 2002. Lupus 2003;12:508-513","DOI":"10.1191\/0961203303lu390oa"},{"key":"#cr-split#-e_1_2_1_9_1.2","doi-asserted-by":"crossref","unstructured":"WARSS APASS PICSS and HAS Study Groups. The feasibility of a collaborative double-blind study using anticoagulant. Cerebrovasc Dis 1997;7: 100-12.","DOI":"10.1159\/000108175"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1191\/0961203303lu392oa"},{"key":"e_1_2_1_11_1","first-page":"1344","article-title":"Font J, von Landenberg P, et al","volume":"31","author":"Shoenfeld Y","year":"2004","unstructured":"Shoenfeld Y, Lev S, Blatt I, Blank M, Font J, von Landenberg P, et al. Features associated with epilepsy in the antiphospholipid syndrome. J Rheumatol 2004;31: 1344\u20138.","journal-title":"Features associated with epilepsy in the antiphospholipid syndrome. J Rheumatol"},{"key":"e_1_2_1_12_1","first-page":"175","article-title":"Appel GB","volume":"10","author":"Joseph RE","year":"2001","unstructured":"Joseph RE, Radhakrishnan J, Appel GB. Antiphospholipid antibody syndrome and renal disease. Curr Opin Nephrol Hypertens 2001;10:175\u201381.","journal-title":"Antiphospholipid antibody syndrome and renal disease. Curr Opin Nephrol Hypertens"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1191\/0961203303lu401oa"},{"key":"e_1_2_1_14_1","first-page":"91","article-title":"Polak-Charcon S, Amital H, et al","volume":"7","author":"Levi Y","year":"1996","unstructured":"Levi Y, Ziporen L, Gilburd B, George J, Polak-Charcon S, Amital H, et al. Membranous nephropathy in primary antiphospholipid syndrome: description of a case and induction of renal injury in SCID mice. Hum Antibod Hybridomas 1996;7:91\u20136.","journal-title":"Membranous nephropathy in primary antiphospholipid syndrome: description of a case and induction of renal injury in SCID mice. Hum Antibod Hybridomas"},{"key":"e_1_2_1_15_1","first-page":"49","article-title":"Amital H, Bar-Dayan Y, et al","volume":"66","author":"Levy Y","year":"1998","unstructured":"Levy Y, George J, Ziporen L, Cledes J, Amital H, Bar-Dayan Y, et al. Massive proteinuria as a main manifestation of primary antiphospholipid syndrome. Pathobiology 1998;66: 49\u201352.","journal-title":"Massive proteinuria as a main manifestation of primary antiphospholipid syndrome. Pathobiology"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","unstructured":"Vianna JL Khamashta MA Ordi-Ros J Font J Cervera R Lopez-Soto A et al. Comparison of the primary and secondary antiphospholipid syndrome: a European Multicenter Study of 114 patients. Am J Med 1994;96: 3\u20139.","DOI":"10.1016\/0002-9343(94)90108-2"},{"key":"e_1_2_1_17_1","first-page":"58","article-title":"Scheibenpflug L","volume":"20","author":"Hillerdal G","year":"1991","unstructured":"Hillerdal G, Hagg A, Licke G, Wegenius G, Scheibenpflug L. Intra-alveolar haemorrhage in the anticardiolipin antibody syndrome. Scand J Rheumatol 1991;20:58\u201362.","journal-title":"Intra-alveolar haemorrhage in the anticardiolipin antibody syndrome. Scand J Rheumatol"},{"key":"e_1_2_1_18_1","first-page":"233","article-title":"Ritter JM","volume":"71","author":"Kelion AD","year":"1995","unstructured":"Kelion AD, Cockcroft JR, Ritter JM. Antiphospholipid syndrome in a patient with rapidly progressive fibrosing alveolitis. Postgrad Med J 1995;71:233\u20135.","journal-title":"Antiphospholipid syndrome in a patient with rapidly progressive fibrosing alveolitis. Postgrad Med J"},{"key":"e_1_2_1_19_1","first-page":"79","article-title":"Vera-Lastra 0, Shoenfeld Y","volume":"25","author":"Jara LJ","year":"2003","unstructured":"Jara LJ, Medina G, Vera-Lastra 0, Shoenfeld Y. Athero-sclerosis and antiphospholipid syndrome. Clin Rev Allergy Immunol 2003;25:79\u201388.","journal-title":"Athero-sclerosis and antiphospholipid syndrome. Clin Rev Allergy Immunol"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1078\/0171-2985-00212"},{"key":"e_1_2_1_21_1","doi-asserted-by":"crossref","unstructured":"Shoenfeld Y Sherer Y Fishman P. Interleukin-3 and pregnancy loss in antiphospholipid syndrome. Scand J Rheumatol 1998;27\\(Supp1)107: 19\u201322.","DOI":"10.1080\/03009742.1998.11720701"},{"key":"e_1_2_1_22_1","doi-asserted-by":"crossref","unstructured":"Shoenfeld Y Sherer Y Blank M. Antiphospholipid syndrome in pregnancy-animal models and clinical implications. Scand J Rheumatol 1998;27\\(Supp1)107: 33\u20136.","DOI":"10.1080\/03009742.1998.11720704"},{"key":"e_1_2_1_23_1","doi-asserted-by":"crossref","unstructured":"Sherer Y Shoenfeld Y. Anti-phospholipid autoantibodies-do they have a pathogenic role in infertility? Scand J Rheumatol 1998;27\\(Supp1)107: 40\u20133.","DOI":"10.1080\/03009742.1998.11720759"},{"key":"e_1_2_1_24_1","first-page":"489","article-title":"Branch DW","volume":"87","author":"Oshiro BT","year":"1996","unstructured":"Oshiro BT, Silver RM, Scott JR, Yu H, Branch DW. Antiphospholipid antibodies and fetal death. Obstet Gynecol 1996;87:489\u201393.","journal-title":"Antiphospholipid antibodies and fetal death. Obstet Gynecol"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.106754"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.8.3069"},{"key":"e_1_2_1_27_1","first-page":"419","article-title":"Winkelmann RK","volume":"120","author":"Alegre VA","year":"1989","unstructured":"Alegre VA, Gastineau DA, Winkelmann RK. Skin lesions associated with circulating lupus anticoagulant. Br J Dermatol 1989;120:419\u201329.","journal-title":"Skin lesions associated with circulating lupus anticoagulant. Br J Dermatol"},{"key":"e_1_2_1_28_1","first-page":"564","volume":"12","author":"Hodak E","year":"2003","unstructured":"Hodak E, Feuerman H, Molad Y, Monselise Y, David M. Primary anetoderma: a cutaneous sign of antiphospholipid antibodies. Lupus 2003;12:564\u20138.","journal-title":"David M. Primary anetoderma: a cutaneous sign of antiphospholipid antibodies. Lupus"},{"key":"e_1_2_1_29_1","first-page":"50","article-title":"Shoenfeld Y","volume":"136","author":"Nahum A","year":"1999","unstructured":"Nahum A, Levy Y, Shoenfeld Y. Ocular manifestations in the antiphospholipid syndrome. Harefuah 1999;136:50\u20133.","journal-title":"Ocular manifestations in the antiphospholipid syndrome. Harefuah"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1191\/0961203303lu394oa"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200111000-00002"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009740252937667"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1053\/sarh.2001.27660"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.10187"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/000313480407000117"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-002-0196-9"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.11435"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.42.358"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0609.2003.00145.x"},{"key":"e_1_2_1_40_1","first-page":"777","article-title":"Massive pulmonary hemorrhage in a Saudi female with primary antiphospholipid syndrome","volume":"21","author":"Al-Hajjaj MS","year":"2000","unstructured":"Al-Hajjaj MS. Massive pulmonary hemorrhage in a Saudi female with primary antiphospholipid syndrome. Saudi Med J 2000;21:777\u20139.","journal-title":"Saudi Med J"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-9071.2004.00766.x"},{"key":"e_1_2_1_42_1","first-page":"313","article-title":"Meyer 0, Kahn MF","volume":"11","author":"Genevay S","year":"2002","unstructured":"Genevay S, Hayem G, Hamza S, Palazzo E, Meyer 0, Kahn MF. Oculomotor palsy in six patients with systemic lupus erythematosus. A possible role of antiphospholipid syndrome. Lupus 2002;11:313\u201316.","journal-title":"Oculomotor palsy in six patients with systemic lupus erythematosus. A possible role of antiphospholipid syndrome. Lupus"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-002-8287-2"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-200011000-00017"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1080\/030097401300162978"},{"key":"e_1_2_1_46_1","first-page":"330","article-title":"Anti-cardiolipin autoantibodies and pulmonary embolism","volume":"29","author":"Ulvestad E","year":"2000","unstructured":"Ulvestad E, Kanestrom A, Tengner P, Gjerde S, Sundal J, Haga HJ. Anti-cardiolipin autoantibodies and pulmonary embolism. A case for a common cause. Scand J Rheumatol 2000;29:330\u20133.","journal-title":"A case for a common cause. Scand J Rheumatol"},{"key":"e_1_2_1_47_1","first-page":"479","article-title":"Neurological manifestations of polyarteritis nodosa associated with the antiphospholipid syndrome","volume":"154","author":"Valeyrie L","year":"2003","unstructured":"Valeyrie L, Bachot N, Roujeau JC, Authier J, Gherardi R, Hosseini H. Neurological manifestations of polyarteritis nodosa associated with the antiphospholipid syndrome. Ann Med Interne (Paris) 2003;154:479\u201382.","journal-title":"Ann Med Interne (Paris)"},{"key":"e_1_2_1_48_1","first-page":"196","article-title":"Antiphospholipid syndrome with renal artery embolism: case report","volume":"3","author":"Safley DM","year":"2002","unstructured":"Safley DM, McCullough PA. Antiphospholipid syndrome with renal artery embolism: case report. Rev Cardiovasc Med 2002;3:196\u2013201.","journal-title":"Rev Cardiovasc Med"},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.86.2.132"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1080\/030097402320318468"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1021716623305"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/17.11.2981"},{"key":"e_1_2_1_53_1","doi-asserted-by":"crossref","unstructured":"Yodfat 0 Blank M Krause I Shoenfeld Y. The pathogenic role of anti-phosphatidylserine antibodies: active immuniza-tion with the antibodies leads to the induction of antiphos-pholipid syndrome. Clin Immunol Immunopathol 1996;78: 14\u201320.","DOI":"10.1006\/clin.1996.0003"},{"key":"e_1_2_1_54_1","first-page":"51","article-title":"al","volume":"49","author":"Von-Landenberg P","year":"2003","unstructured":"Von-Landenberg P, Matthias T, Zaech J, Schultz M, Lorber M, Blank M, et al. Antiprothrombin antibodies are associated with pregnancy loss in patients with the antiphospholipid syndrome. Am J Reprod Immunol 2003;49:51\u20136.","journal-title":"Antiprothrombin antibodies are associated with pregnancy loss in patients with the antiphospholipid syndrome. Am J Reprod Immunol"},{"key":"e_1_2_1_55_1","doi-asserted-by":"crossref","unstructured":"Galli M. Which antiphospholipid antibodies should be measured in the antiphospholipid syndrome? Haemostasis 2000;30 Suppl. 2:57\u201362.","DOI":"10.1159\/000054164"},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1006\/jaut.1994.1032"},{"key":"e_1_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199907)42:7<1309::AID-ANR1>3.0.CO;2-F"},{"key":"e_1_2_1_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200002)43:2<440::AID-ANR26>3.0.CO;2-N"},{"key":"e_1_2_1_59_1","first-page":"457","volume":"10","author":"Wilson WA","year":"2001","unstructured":"Wilson WA, Gharavi AE, Piette JC. International classifica-tion criteria for antiphospholipid syndrome: synopsis of a post-conference workshop held at the Ninth International (Tours) aPL Symposium. Lupus 2001;10:457\u201360.","journal-title":"Piette JC. International classifica-tion criteria for antiphospholipid syndrome: synopsis of a post-conference workshop held at the Ninth International (Tours) aPL Symposium. Lupus"},{"key":"e_1_2_1_60_1","doi-asserted-by":"crossref","unstructured":"Piette JC. Towards improved criteria for the antiphospholipid syndrome. Lupus 1998;7(Suppl): S149\u201357.","DOI":"10.1177\/096120339800700233"},{"key":"e_1_2_1_61_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2003.006163"},{"key":"e_1_2_1_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4906(02)00007-8"},{"key":"e_1_2_1_63_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0212337"},{"key":"e_1_2_1_64_1","first-page":"545","article-title":"Colden-Stanfield M, Harris EN","volume":"46","author":"Gharavi AE","year":"2002","unstructured":"Gharavi AE, Pierangeli SS, Espinola RG, Liu X, Colden-Stanfield M, Harris EN. Antiphospholipid antibodies induced in mice by immunization with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo. Arthritis Rheum 2002;46:545\u201352.","journal-title":"Antiphospholipid antibodies induced in mice by immunization with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo. Arthritis Rheum"},{"key":"e_1_2_1_65_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.200116116"},{"key":"e_1_2_1_66_1","doi-asserted-by":"publisher","DOI":"10.1161\/hh0102.102795"},{"key":"e_1_2_1_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2004.02497.x"},{"key":"e_1_2_1_68_1","first-page":"1067","article-title":"Alarcon-Sergovia D, Perez-Vazquez ME","volume":"21","author":"Drenkard C","year":"1994","unstructured":"Drenkard C, Villa AR, Alarcon-Sergovia D, Perez-Vazquez ME. Influence of the antiphospholipid syndrome in the survival of patients with systemic lupus erythematosus. J Rheumatol 1994;21:1067\u201372.","journal-title":"Influence of the antiphospholipid syndrome in the survival of patients with systemic lupus erythematosus. J Rheumatol"},{"key":"e_1_2_1_69_1","first-page":"79","article-title":"Vera-Lastra 0, Shoenfeld Y","volume":"1","author":"Jara LJ","year":"2003","unstructured":"Jara LJ, Medina G, Vera-Lastra 0, Shoenfeld Y. Atherosclerosis and antiphospholipid syndrome. Clin Rev Allergy Immunol 2003;1:79\u201388.","journal-title":"Atherosclerosis and antiphospholipid syndrome. Clin Rev Allergy Immunol"},{"key":"e_1_2_1_70_1","doi-asserted-by":"publisher","DOI":"10.1191\/096120398678919624"},{"key":"e_1_2_1_71_1","doi-asserted-by":"publisher","DOI":"10.1191\/0961203303lu389oa"},{"key":"e_1_2_1_72_1","first-page":"490","article-title":"Long term anticoagulation is preferable for patients with antiphospho-lipid antibody syndrome: result of a decision analysis","volume":"29","author":"Brunner HI","year":"2002","unstructured":"Brunner HI, Chan WS, Ginsberg JS, Feldman BM. Long term anticoagulation is preferable for patients with antiphospho-lipid antibody syndrome: result of a decision analysis. J Rheumatol 2002;29:490\u2013501.","journal-title":"J Rheumatol"},{"key":"e_1_2_1_73_1","first-page":"3685","article-title":"Brill-Edwards P, Donovan D, Moffatt K, Johnston M, et al","volume":"86","author":"Ginsberg JS","year":"1995","unstructured":"Ginsberg JS, Wells PS, Brill-Edwards P, Donovan D, Moffatt K, Johnston M, et al. Antiphospholipid antibodies and venous thromboembolism. Blood 1995;86:3685\u201391.","journal-title":"Antiphospholipid antibodies and venous thromboembolism. Blood"},{"key":"e_1_2_1_74_1","first-page":"859","article-title":"Girolami A","volume":"75","author":"Prandoni P","year":"1996","unstructured":"Prandoni P, Simioni P, Girolami A. Antiphospholipid antibodies, recurrent thromboembolism, and intensity of warfarin anticoagulation. Thromb Haemost 1996;75:859.","journal-title":"Antiphospholipid antibodies, recurrent thromboembolism, and intensity of warfarin anticoagulation. Thromb Haemost"},{"key":"e_1_2_1_75_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-117-4-303"},{"key":"e_1_2_1_76_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199504133321504"},{"key":"e_1_2_1_77_1","doi-asserted-by":"crossref","unstructured":"Vianna JL Khamashta MA Ordi-Ros J Font J Cervera R Lopez-Soto A et al. Comparison of the primary and secondary antiphospholipid syndrome: a European multi-center study of 114 patients. Am J Med 1994;96: 3\u20139.","DOI":"10.1016\/0002-9343(94)90108-2"},{"key":"e_1_2_1_78_1","first-page":"657","article-title":"Singer DE","volume":"279","author":"Hylek EM","year":"1998","unstructured":"Hylek EM, Heiman H, Skates SJ, Sheehan MA, Singer DE. Acetominophen and other risk factors for excessive warfarin anticoagulation. J Am Med Assoc 1998;279:657\u201362.","journal-title":"Acetominophen and other risk factors for excessive warfarin anticoagulation. J Am Med Assoc"},{"key":"e_1_2_1_79_1","first-page":"99","article-title":"Control of oral anticoagulation in patients with antiphospholipid syndrome","volume":"80","author":"Robert A","year":"1998","unstructured":"Robert A, Le Querrec A, Delahousse B, Caron C, Houbouyan L, Boutiere B, et al. Control of oral anticoagulation in patients with antiphospholipid syndrome. Influence of the lupus anticoagulant on international normalized ratio. Thromb Haemost 1998;80:99\u2013103.","journal-title":"Influence of the lupus anticoagulant on international normalized ratio. Thromb Haemost"},{"key":"e_1_2_1_80_1","first-page":"518","article-title":"Cardiac disease in the antiphospholipid syndrome: recommendations for treatment","volume":"12","author":"Lockshin M","year":"2003","unstructured":"Lockshin M, Tenedios F, Petri M, McCarty G, Forastiero R, Krilis S, et al. Cardiac disease in the antiphospholipid syndrome: recommendations for treatment. Committee con-sensus report. Lupus 2003;12:518\u201323.","journal-title":"Committee con-sensus report. Lupus"},{"key":"e_1_2_1_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200106)44:6<1466::AID-ART242>3.0.CO;2-C"},{"key":"e_1_2_1_82_1","doi-asserted-by":"publisher","DOI":"10.1191\/0961203303lu393oa"},{"key":"e_1_2_1_83_1","first-page":"843","article-title":"Perioperative medical management of antiphospholipid syndrome: hospital for special surgery experience, review of literature, and recommendations","volume":"29","author":"Erkan D","year":"2002","unstructured":"Erkan D, Leibowitz E, Berman J, Lockshin MD. Perioperative medical management of antiphospholipid syndrome: hospital for special surgery experience, review of literature, and recommendations. J Rheumatol 2002;29:843\u20139.","journal-title":"J Rheumatol"},{"key":"e_1_2_1_84_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-003-0031-7"},{"key":"e_1_2_1_85_1","first-page":"530","article-title":"Catastrophic Antiphospholipid Syndrome Registry Project Group","volume":"62","author":"Erkan D","year":"2003","unstructured":"Erkan D, Asherson RA, Espinosa G, Cervera R, Font J, Piette JC, et al. Catastrophic Antiphospholipid Syndrome Registry Project Group. Long term outcome of catastrophic antiphospholipid syndrome survivors. Ann Rheum Dis 2003;62:530\u20133.","journal-title":"Long term outcome of catastrophic antiphospholipid syndrome survivors. Ann Rheum Dis"},{"key":"e_1_2_1_86_1","first-page":"499","volume":"12","author":"Alarcon-Segovia D","year":"2003","unstructured":"Alarcon-Segovia D, Boffa MC, Branch W, Cervera R, Gharavi A, Khamashta M, et al. Prophylaxis of the antiphospholipid syndrome: a consensus report. Lupus 2003;12:499\u2013503.","journal-title":"al. Prophylaxis of the antiphospholipid syndrome: a consensus report. Lupus"},{"key":"e_1_2_1_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20120"},{"key":"e_1_2_1_88_1","unstructured":"Blank M Sherer Y Shoenfeld Y In: Asherson RA Cervera R Piette JC Shoenfeld Y editors. The Antiphospholipid Syndrome II. Amsterdam: Elsevier 2000:421\u201330."},{"key":"e_1_2_1_89_1","first-page":"5164","article-title":"Fridkin M, Katchalski-Katzir E","volume":"96","author":"Blank M","year":"1999","unstructured":"Blank M, Shoenfeld Y, Cabilly S, Heldman Y, Fridkin M, Katchalski-Katzir E. Prevention of experimental antiphos-pholipid syndrome and endothelial cell activation by synthetic peptides. Proc Natl Acad Sci 1999;96:5164\u20138.","journal-title":"Prevention of experimental antiphos-pholipid syndrome and endothelial cell activation by synthetic peptides. Proc Natl Acad Sci"}],"container-title":["Scandinavian Journal of Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/03009740410010290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T14:00:47Z","timestamp":1770904847000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/03009740410010290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12,31]]},"references-count":89,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,12,31]]}},"alternative-id":["10.1080\/03009740410010290"],"URL":"https:\/\/doi.org\/10.1080\/03009740410010290","relation":{},"ISSN":["0300-9742","1502-7732"],"issn-type":[{"value":"0300-9742","type":"print"},{"value":"1502-7732","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,12,31]]}}}