{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T09:26:18Z","timestamp":1793870778482,"version":"4.6.1"},"reference-count":36,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T00:00:00Z","timestamp":1793836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Avian Pathology"],"DOI":"10.1080\/03079457.2026.2733059","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:44:10Z","timestamp":1789382650000},"page":"1-14","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of recombinant HVT+IBD+H5 vaccine against novel variant infectious bursal disease, A2dB1b, in broiler and SPF chickens"],"prefix":"10.1080","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7907-0102","authenticated-orcid":false,"given":"Samir A.","family":"Nassif","sequence":"first","affiliation":[{"name":"ARC","place":["Cairo, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4322-6865","authenticated-orcid":false,"given":"Ahlam","family":"Mourad","sequence":"additional","affiliation":[{"name":"ARC","place":["Cairo, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3236-512X","authenticated-orcid":false,"given":"Esraa","family":"Fouad","sequence":"additional","affiliation":[{"name":"ARC","place":["Cairo, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8830-520X","authenticated-orcid":false,"given":"Rania A.","family":"Abu Zaid","sequence":"additional","affiliation":[{"name":"ARC","place":["Cairo, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8068-6094","authenticated-orcid":false,"given":"Marwa S.","family":"Khattab","sequence":"additional","affiliation":[{"name":"Cairo University","place":["Giza, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Ashry","sequence":"additional","affiliation":[{"name":"Boehringer Ingelheim Animal Health","place":["New Cairo, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Radwan","sequence":"additional","affiliation":[{"name":"Boehringer Ingelheim Animal Health","place":["New Cairo, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali E.","family":"Khalifa","sequence":"additional","affiliation":[{"name":"Boehringer Ingelheim Animal Health","place":["New Cairo, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1767-4557","authenticated-orcid":false,"given":"Jose L. L.","family":"Torres","sequence":"additional","affiliation":[{"name":"Boehringer Ingelheim Animal Health","place":["Lyon, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taoufik","family":"Rawi","sequence":"additional","affiliation":[{"name":"Boehringer Ingelheim Animal Health","place":["Lyon, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1272-153X","authenticated-orcid":false,"given":"Ahmed R.","family":"Elbestawy","sequence":"additional","affiliation":[{"name":"Menoufia University","place":["Menoufia, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,11,5]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0003-9098(25)00053-0","article-title":"Typing of infectious bursal disease viruses from field outbreaks in Egypt and the protection efficacy of commercial vaccines under experimental condition","volume":"68","author":"Aly M.M.","year":"2004","unstructured":"Aly, M.M., Hassan, M.K. & Ahmed, A.A.S. (2004). Typing of infectious bursal disease viruses from field outbreaks in Egypt and the protection efficacy of commercial vaccines under experimental condition. European Poultry Science, 68, 241\u2013246.","journal-title":"European Poultry Science"},{"key":"e_1_3_2_3_1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.21608\/jvmr.2005.77945","article-title":"Studies on recent IBD virus field variant isolates: genomic identification and differentiation using RT-PCR-RFLP","volume":"15","author":"Amer M.M.","year":"2005","unstructured":"Amer, M.M. & Nassif, S.A. (2005). Studies on recent IBD virus field variant isolates: genomic identification and differentiation using RT-PCR-RFLP. Journal of Veterinary Medical Research, 15, 134\u2013138.","journal-title":"Journal of Veterinary Medical Research"},{"key":"e_1_3_2_4_1","first-page":"250","article-title":"Histopathological evaluation of the effects of live infectious bursal disease vaccine originated from WF2512 strain on bursa Fabricius in the broilers","volume":"7","author":"Ate\u015f M.B.","year":"2022","unstructured":"Ate\u015f, M.B., \u00c7elik, Z., Sal\u0131k, R., Da\u011far, O., Bulut, A., Tural, A. & \u00d6zdemir, \u00d6. (2022). Histopathological evaluation of the effects of live infectious bursal disease vaccine originated from WF2512 strain on bursa Fabricius in the broilers. Journal of Advanced Veterinary Bio Science and Technology, 7, 250\u2013258.","journal-title":"Journal of Advanced Veterinary Bio Science and Technology"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2004.08.019"},{"key":"e_1_3_2_6_1","first-page":"1","article-title":"Virus mutations and their impact on vaccination against infectious bursal disease (Gumboro disease)","volume":"35","author":"Boudaoud A.","year":"2016","unstructured":"Boudaoud, A., Mamache, B., Tombari, W. & Ghram, A. (2016). Virus mutations and their impact on vaccination against infectious bursal disease (Gumboro disease). Revue Scientifique et Technique, 35, 1\u201329.","journal-title":"Revue Scientifique et Technique"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1637\/aviandiseases-D-23-99987"},{"key":"e_1_3_2_8_1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1590\/S1517-83822009000100036","article-title":"Sequencing and phylogenetic analysis of the infectious bursal disease virus isolates from outbreak in layer flocks in the state of Minas Gerais","volume":"40","author":"Dias C.C.","year":"2009","unstructured":"Dias, C.C., de Oliveira Souza, F., da Silva, E.M., Eller, M.R., Barrios, P.R., Dos Santos, B.M., Moraes, M.P. & de Almeida, M.R. (2009). Sequencing and phylogenetic analysis of the infectious bursal disease virus isolates from outbreak in layer flocks in the state of Minas Gerais. Brazilian Journal of Microbiology, 40, 205\u2013207.","journal-title":"Brazilian Journal of Microbiology"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1556\/avet.2014.003"},{"key":"e_1_3_2_10_1","first-page":"264","volume-title":"Proceedings of the 2nd Scientific Conference of the Egyptian Veterinary Poultry Association","author":"El-Batrawi A.M.","year":"1990","unstructured":"El-Batrawi, A.M. & El-Kady, M.F. (1990). Studies on severe outbreaks of infectious bursal disease: determination of the critical age of susceptibility in maternally immune chicks. In Proceedings of the 2nd Scientific Conference of the Egyptian Veterinary Poultry Association (pp. 264\u2013269). Cairo."},{"key":"e_1_3_2_11_1","first-page":"234","article-title":"Effect of aflatoxin-induced immunosuppression on pathogenesis of H9N2 avian influenza virus","volume":"34","author":"El Miniawy H.M.","year":"2014","unstructured":"El Miniawy, H.M., Ahmed, K.A., El-Sanousi, A.A. & & Khattab, M.M.S. (2014). Effect of aflatoxin-induced immunosuppression on pathogenesis of H9N2 avian influenza virus. Pakistan Veterinary Journal, 34, 234\u2013238.","journal-title":"Pakistan Veterinary Journal"},{"key":"e_1_3_2_12_1","first-page":"300","article-title":"Infectious bursal disease virus infection among Egyptian flocks. III. antigenic characterization of IBDV by the antigen-capture ELISA (AC-ELISA) using monoclonal antibodies (MAbs)","volume":"4","author":"El-Sanousi A.","year":"1994","unstructured":"El-Sanousi, A., Madbouly, H.M., Saber, M.S., El-Bagoury, C.F., Abd El-Bar, N.A., Batrawi, A. & Reda, I.M. (1994). Infectious bursal disease virus infection among Egyptian flocks. III. antigenic characterization of IBDV by the antigen-capture ELISA (AC-ELISA) using monoclonal antibodies (MAbs). Journal of Veterinary Medical Research, 4, 300\u2013308.","journal-title":"Journal of Veterinary Medical Research"},{"key":"e_1_3_2_13_1","first-page":"7","article-title":"A preliminary investigation on the occurrence of Gumboro disease in Egypt (chickens)","volume":"11","author":"El-Sergany H.","year":"1974","unstructured":"El-Sergany, H., Moursi, A., Saber, M.S. & Mohamed, M.A. (1974). A preliminary investigation on the occurrence of Gumboro disease in Egypt (chickens). Journal of Veterinary Science, 11, 7\u201314.","journal-title":"Journal of Veterinary Science"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119371199.ch7"},{"issue":"8255","key":"e_1_3_2_15_1","first-page":"1","article-title":"Genetic insight into the interaction of IBDV with host\u2014a clue to the development of novel IBDV vaccines","volume":"24","author":"Gao H.","year":"2023","unstructured":"Gao, H., Wang, Y., Gao, L. & Zheng, S. J. (2023). Genetic insight into the interaction of IBDV with host\u2014a clue to the development of novel IBDV vaccines. International Journal of Molecular Sciences, 24(8255), 1\u201317.","journal-title":"International Journal of Molecular Sciences"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:VERC.0000026657.29702.4e"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1637\/0005-2086-65.3.438"},{"key":"e_1_3_2_18_1","doi-asserted-by":"crossref","first-page":"445","DOI":"10.21608\/vmjg.2003.375378","article-title":"Transmissible viral proventriculitis and stunting syndrome in broiler chickens in Egypt. I isolation and characterization of variant infectious bursal disease virus","volume":"51","author":"Hussein A.H.","year":"2003","unstructured":"Hussein, A.H., Aly, A.N., Sultan, H. & Al-Safty, M. (2003). Transmissible viral proventriculitis and stunting syndrome in broiler chickens in Egypt. I isolation and characterization of variant infectious bursal disease virus. The Veterinary Medical Journal (Giza), 51, 445\u2013462.","journal-title":"The Veterinary Medical Journal (Giza)"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.2307\/1591028"},{"issue":"2388","key":"e_1_3_2_20_1","first-page":"1","article-title":"First detection and molecular characterization of novel variant infectious bursal disease virus (genotype A2dB1b)in Egypt","volume":"15","author":"Legnardi M.","year":"2023","unstructured":"Legnardi, M., Poletto, F., Talaat, S., Selim, K., Moawad, M.K., Franzo, G., Tucciarone, C.M., Cecchinato, M. & Sultan, H. (2023). First detection and molecular characterization of novel variant infectious bursal disease virus (genotype A2dB1b)in Egypt. Viruses, 15(2388), 1\u201314.","journal-title":"Viruses"},{"key":"e_1_3_2_21_1","doi-asserted-by":"crossref","first-page":"380","DOI":"10.4149\/av_2019_402","article-title":"Molecular detection of Marek\u2019s disease virus in feather and blood samples from young laying hens in Colombia","volume":"63","author":"L\u00f3pez-Osorio S.","year":"2019","unstructured":"L\u00f3pez-Osorio, S., Villar, D., Piedrahita, D., Ram\u00edrez-Nieto, G., Nair, V., Baigent, S. & Chaparro-Guti\u00e9rrez, J. (2019). Molecular detection of Marek\u2019s disease virus in feather and blood samples from young laying hens in Colombia. Acta Virologica, 63, 380\u2013391.","journal-title":"Acta Virologica"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.21608\/vmjg.2003.375142"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-017-3500-4"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2003.08.005"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.104.15.332"},{"key":"e_1_3_2_26_1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.5897\/JVMAH2016.0456","article-title":"Bursa body index as a visual indicator for the assessment of bursa of Fabricius","volume":"9","author":"Raji A.","year":"2017","unstructured":"Raji, A., Mohammed, B., Oladele, S.B., Saidu, L., Jibril, A.H. & Cazaban, C. (2017). Bursa body index as a visual indicator for the assessment of bursa of Fabricius. Journal of Veterinary Medicine and Animal Health, 9, 32\u201338.","journal-title":"Journal of Veterinary Medicine and Animal Health"},{"key":"e_1_3_2_27_1","first-page":"357","article-title":"Isolation and characterization of variant infectious bursal disease viruses","volume":"189","author":"Rosenberger J.K.","year":"1986","unstructured":"Rosenberger, J.K. & Cloud, S.S. (1986). Isolation and characterization of variant infectious bursal disease viruses. Journal of the American Veterinary Medical Association, 189, 357\u2013411.","journal-title":"Journal of the American Veterinary Medical Association"},{"issue":"2","key":"e_1_3_2_28_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/vetsci11020098","article-title":"Isolation, molecular, and histopathological patterns of a novel variant of infectious bursal disease virus in chicken flocks in Egypt","volume":"11","author":"Salaheldin A.H.","year":"2024","unstructured":"Salaheldin, A.H., Abd El-Hamid, H.S., Ellakany, H.F., Mohamed, M.A. & Elbestawy, A.R. (2024). Isolation, molecular, and histopathological patterns of a novel variant of infectious bursal disease virus in chicken flocks in Egypt. Veterinary Sciences, 11(2), 98, 1\u201316.","journal-title":"Veterinary Sciences"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/03079457.2024.2348513"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.2307\/1591076"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/03079459008418695"},{"key":"e_1_3_2_32_1","volume-title":"Bancroft\u2019s theory and practice of histological techniques","author":"Suvarna S.K.","year":"2012","unstructured":"Suvarna, S.K., Layton, C. & Bancroft, J.D. (2012). Bancroft\u2019s theory and practice of histological techniques (7th ed.). Oxford: Churchill Livingstone.","edition":"7"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/03079459108418779"},{"key":"e_1_3_2_34_1","first-page":"1","volume-title":"Manual of diagnostic tests and vaccines for terrestrial animals","author":"World Organisation for Animal Health (WOAH).","year":"2021","unstructured":"World Organisation for Animal Health (WOAH). (2021). Avian influenza (including infection with high pathogenicity avian influenza viruses). In Manual of diagnostic tests and vaccines for terrestrial animals. (Chap. 3.3.4, pp. 1\u201329). Paris, France: WOAH. https:\/\/www.woah.org\/fileadmin\/Home\/eng\/Health_standards\/tahm\/3.03.04_AI.pdf"},{"key":"e_1_3_2_35_1","first-page":"1","volume-title":"Manual of diagnostic tests and vaccines for terrestrial animals","author":"World Organisation for Animal Health (WOAH).","year":"2024","unstructured":"World Organisation for Animal Health (WOAH). (2024). Infectious bursal disease (Gumboro disease). In Manual of diagnostic tests and vaccines for terrestrial animals. (Chap. 3.3.12, pp. 1\u201318). Paris, France: WOAH."},{"key":"e_1_3_2_36_1","first-page":"255","article-title":"A 5-year study of the incidence and economic impact of variant infectious bursal disease viruses on broiler production in Saskatchewan, Canada","volume":"80","author":"Zachar T.","year":"2016","unstructured":"Zachar, T., Popowich, S., Goodhope, B., Knezacek, T., Ojkic, D., Willson, P., Ahmed, K.A. & Gomis, S. (2016). A 5-year study of the incidence and economic impact of variant infectious bursal disease viruses on broiler production in Saskatchewan, Canada. Canadian Journal of Veterinary Research, 80, 255\u2013261.","journal-title":"Canadian Journal of Veterinary Research"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/v14102253"}],"container-title":["Avian Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/03079457.2026.2733059","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/03079457.2026.2733059","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/03079457.2026.2733059","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T08:39:59Z","timestamp":1793867999000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/03079457.2026.2733059"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11,5]]},"references-count":36,"alternative-id":["10.1080\/03079457.2026.2733059"],"URL":"https:\/\/doi.org\/10.1080\/03079457.2026.2733059","relation":{},"ISSN":["0307-9457","1465-3338"],"issn-type":[{"value":"0307-9457","type":"print"},{"value":"1465-3338","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,11,5]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=cavp20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=cavp20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2026-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-14","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-11-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}