{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T18:46:29Z","timestamp":1754160389248,"version":"3.41.2"},"reference-count":51,"publisher":"Informa UK Limited","issue":"8","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Drug Development and Industrial Pharmacy"],"published-print":{"date-parts":[[2025,8,3]]},"DOI":"10.1080\/03639045.2025.2519976","type":"journal-article","created":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T03:46:18Z","timestamp":1749699978000},"page":"955-962","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["Hypolipidemic and HMG-CoA reductase inhibitory effects of 15-oxoursolic acid from\n            <i>Rhododendron arboreum<\/i>\n            : An\n            <i>In-vivo<\/i>\n            and\n            <i>In-silico<\/i>\n            study"],"prefix":"10.1080","volume":"51","author":[{"given":"Sajid","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Chemistry, Bacha Khan University","place":["Charsadda, Pakistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Usman","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Bacha Khan University","place":["Charsadda, Pakistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Ishtiaq","family":"Jan","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Kohat University of Science and Technology","place":["Kohat, Pakistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"issue":"1","key":"e_1_3_2_2_1","first-page":"81","article-title":"Hypolipidemic activity of luffa Aegiptiaca fruits in cholesterol fed hypercholesterolemic rabbits","volume":"2","author":"Thayyil AH","year":"2011","unstructured":"Thayyil AH, Surulivel MKM, Ahmed MF, et\u00a0al. Hypolipidemic activity of luffa Aegiptiaca fruits in cholesterol fed hypercholesterolemic rabbits. Int. J. Pharm. Appl. 2011;2(1):81\u201388.","journal-title":"Int. J. Pharm. Appl"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2007.05.002"},{"issue":"20","key":"e_1_3_2_4_1","first-page":"2113","article-title":"Lipid-lowering mechanisms of grape seed extract (Vitis Vinifera L) and its antihyperlidemic activity","volume":"4","author":"Adisakwattana S","year":"2010","unstructured":"Adisakwattana S, Moonrat J, Srichairat S, et\u00a0al. Lipid-lowering mechanisms of grape seed extract (Vitis Vinifera L) and its antihyperlidemic activity. J. Med. Plants Res. 2010;4(20):2113\u20132120.","journal-title":"J. Med. Plants Res"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2001.tb00172.x"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.13.1681"},{"issue":"11","key":"e_1_3_2_7_1","first-page":"2261","article-title":"Lipid-lowering effects of coriolus versicolor extract in poloxamer 407-induced hypercholesterolaemic rats and high cholesterol-fed rats","volume":"5","author":"Hor SY","year":"2011","unstructured":"Hor SY, Farsi E, Yam MF, et\u00a0al. Lipid-lowering effects of coriolus versicolor extract in poloxamer 407-induced hypercholesterolaemic rats and high cholesterol-fed rats. J. Med. Plants Res. 2011;5(11):2261\u20132266.","journal-title":"J. Med. Plants Res"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061922"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1270956"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.9.3564"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/np990633v"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-894X(01)00647-3"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1248\/cpb.47.141"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.2478\/s11535-010-0045-x"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-962441"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/np50068a041"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-8741(95)90032-2"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-511X-13-131"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/13880209.2017.1343359"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0367-326X(01)00348-3"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/18.6.499"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1298379"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imu.2016.06.001"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-015-0013-6"},{"key":"e_1_3_2_25_1","article-title":"In-silico analysis of secondary metabolites that modulates enzymes of cholesterol target","author":"Marahatha R","year":"2020","unstructured":"Marahatha R, Basnet S, Bhattarai BR, et\u00a0al. In-silico analysis of secondary metabolites that modulates enzymes of cholesterol target. bioRxiv. 2020; .","journal-title":"bioRxiv"},{"issue":"1","key":"e_1_3_2_26_1","first-page":"001","article-title":"Towards understanding the regulation of rubber biosynthesis: insights into the initiator and elongator enzymes","volume":"2","author":"Punetha A","year":"2010","unstructured":"Punetha A, Muthukumaran J, Hemrom AJ, et\u00a0al. Towards understanding the regulation of rubber biosynthesis: insights into the initiator and elongator enzymes. J. Bioinforma. Seq. Anal. 2010;2(1):001\u2013010.","journal-title":"J. Bioinforma. Seq. Anal"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky473"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/11779322211011140"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.4103\/0250-474X.73905"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.1c00298"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.0c05720"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2018.05.026"},{"issue":"9","key":"e_1_3_2_33_1","first-page":"826","article-title":"Prospects for the development of novel anti-hyperlipidemic drugs","volume":"7","author":"Derosa G","year":"2006","unstructured":"Derosa G, Salvadeo S, Cicero AFG. Prospects for the development of novel anti-hyperlipidemic drugs. Curr Opin Investig Drugs. 2006;7(9):826\u2013833.","journal-title":"Curr Opin Investig Drugs"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/861924"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154233"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1183598"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2018.06.882"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.2220\/biomedres.31.213"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-511X-11-98"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.5567\/pharmacologia.2013.170.179"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vph.2006.12.005"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2009.04.008"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.06.080"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.5b00104"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.37358\/RC.18.4.6210"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky318"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S84641"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jksus.2021.101707"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1134\/S0036023617030068"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1280118"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.17305\/bjbms.2013.2389"},{"issue":"2","key":"e_1_3_2_52_1","first-page":"105","article-title":"Study on Biochemical Indices of Liver Function Tests of Albino Rats Supplemented with Three Sources of Vegetable Oils","volume":"19","author":"Imafidon KE","year":"2012","unstructured":"Imafidon KE, Okunrobo LO. Study on Biochemical Indices of Liver Function Tests of Albino Rats Supplemented with Three Sources of Vegetable Oils. Niger. J. Basic Appl. Sci. 2012;19(2):105\u2013110.","journal-title":"Niger. J. Basic Appl. Sci"}],"container-title":["Drug Development and Industrial Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/03639045.2025.2519976","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T13:35:40Z","timestamp":1753536940000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/03639045.2025.2519976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,18]]},"references-count":51,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8,3]]}},"alternative-id":["10.1080\/03639045.2025.2519976"],"URL":"https:\/\/doi.org\/10.1080\/03639045.2025.2519976","relation":{},"ISSN":["0363-9045","1520-5762"],"issn-type":[{"type":"print","value":"0363-9045"},{"type":"electronic","value":"1520-5762"}],"subject":[],"published":{"date-parts":[[2025,6,18]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iddi20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iddi20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-03-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-22","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}