{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T11:18:46Z","timestamp":1775819926530,"version":"3.50.1"},"reference-count":86,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American College of Nutrition"],"published-print":{"date-parts":[[2003,2]]},"DOI":"10.1080\/07315724.2003.10719270","type":"journal-article","created":{"date-parts":[[2013,6,19]],"date-time":"2013-06-19T14:09:33Z","timestamp":1371650973000},"page":"1-8","source":"Crossref","is-referenced-by-count":68,"title":["Folate: A Key to Optimizing Health and Reducing Disease Risk in the Elderly"],"prefix":"10.1080","volume":"22","author":[{"given":"Gail C.","family":"Rampersaud","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gail P.A.","family":"Kauwell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynn B.","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","reference":[{"key":"R2","doi-asserted-by":"crossref","first-page":"S148","DOI":"10.1038\/sj.ejcn.1601037","volume":"54","year":"2000","journal-title":"Eur J Clin Nutr"},{"key":"R3","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1038\/sj.ejcn.1600362","volume":"51","year":"1997","journal-title":"Eur J Clin Nutr"},{"key":"R4","first-page":"8781","year":"1996","journal-title":"\u201cAmendment of the Standards of Identity for Enriched Grain Products to Require Addition of Folic Acid. Final Rule.\u201d"},{"key":"R5","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1093\/ajcn\/46.6.1016","volume":"46","year":"1987","journal-title":"Am J Clin Nutr"},{"key":"R6","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1093\/ajcn\/66.6.1388","volume":"66","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"R7","unstructured":"Institute of Medicine, Food and Nutrition Board:\u201cDietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline.\u201d Washington, DC: National Academy Press,1998 ."},{"key":"R8","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/S0002-8223(00)00027-4","volume":"100","year":"2000","journal-title":"J Am Diet Assoc"},{"key":"R9","first-page":"214","year":"2001","journal-title":"\u201cPresent Knowledge in Nutrition,\u201d"},{"key":"R10","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/(SICI)1097-4652(200005)183:2<145::AID-JCP1>3.0.CO;2-V","volume":"183","year":"2000","journal-title":"J Cell Physiol"},{"key":"R11","first-page":"414","volume":"43","year":"1988","journal-title":"Am J Hum Genet"},{"key":"R12","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/jn\/129.5.919","volume":"129","year":"1999","journal-title":"J Nutr"},{"key":"R13","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1161\/01.CIR.93.1.7","volume":"93","year":"1996","journal-title":"Circulation"},{"key":"R14","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1053\/meta.2000.16555","volume":"49","year":"2000","journal-title":"Metabolism"},{"key":"R15","first-page":"S47","volume":"56","year":"1998","journal-title":"Nutr Rev"},{"key":"R16","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1093\/oxfordjournals.aje.a010290","volume":"151","year":"2000","journal-title":"Am J Epidemiol"},{"key":"R17","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1093\/jn\/130.6.1584","volume":"130","year":"2000","journal-title":"J Nutr"},{"key":"R18","unstructured":"Food and Nutrition Board:\u201cRecommended Dietary Allowances,\u201d 10th ed. Washington, DC: National Academy of Science,1989 ."},{"key":"R19","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S0002-8223(99)00174-1","volume":"99","year":"1999","journal-title":"J Am Diet Assoc"},{"key":"R20","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1146\/annurev.nutr.19.1.357","volume":"19","year":"1999","journal-title":"Annu Rev Nutr"},{"key":"R21","first-page":"65","volume":"36","year":"1999","journal-title":"Semin Hematol"},{"key":"R22","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1056\/NEJM200005113421911","volume":"342","year":"2000","journal-title":"N Eng J Med"},{"key":"R23","first-page":"53305","volume":"58","year":"1993","journal-title":"Fed Regist"},{"key":"R24","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1056\/NEJM199905133401901","volume":"340","year":"1999","journal-title":"N Engl J Med"},{"key":"R25","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1093\/jn\/131.12.3277","volume":"131","year":"2001","journal-title":"J Nutr"},{"key":"R26","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1080\/07315724.2001.10719039","volume":"20","year":"2001","journal-title":"J Am Coll Nutr"},{"key":"R27","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1093\/jn\/126.12.3025","volume":"126","year":"1996","journal-title":"J Nutr"},{"key":"R28","unstructured":"U.S. Department of Health and Human Services:\u201cUse of Dietary Supplements in the United States, 1988\u201394.\u201d Series 11: Data from the National Health Examination Survey, the National Health and Nutrition Examination Surveys and the Hispanic Health and Nutrition Examination Survey No. 244. DHHS Publication No. 99\u20131694. Hyattsville, MD: National Center for Health Statistics,1999 ."},{"key":"R29","doi-asserted-by":"crossref","first-page":"M613","DOI":"10.1093\/gerona\/55.10.M613","volume":"55","year":"2000","journal-title":"J Gerontol"},{"key":"R30","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1093\/ajcn\/73.3.628","volume":"73","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"R31","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0049-0172(98)80049-8","volume":"27","year":"1998","journal-title":"Semin Arthritis Rheum"},{"key":"R32","first-page":"459","volume":"13","year":"1995","journal-title":"Clin Exp Rheumatol"},{"key":"R33","first-page":"830","volume":"24","year":"1997","journal-title":"J Rheumatol"},{"key":"R34","first-page":"441","volume":"25","year":"1998","journal-title":"J Rheumatol"},{"key":"R35","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1136\/ard.58.2.79","volume":"58","year":"1999","journal-title":"Ann Rheum Dis"},{"key":"R36","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1080\/030097401753180408","volume":"30","year":"2001","journal-title":"Scan J Rheumatol"},{"key":"R37","first-page":"36","volume":"25","year":"1998","journal-title":"J Rheumatol"},{"key":"R38","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1002\/1529-0131(200107)44:7<1515::AID-ART273>3.0.CO;2-7","volume":"44","year":"2001","journal-title":"Arthritis Rheum"},{"key":"R39","first-page":"313","year":"1995","journal-title":"\u201cFolate in Health and Disease.\u201d"},{"key":"R40","doi-asserted-by":"crossref","first-page":"933","DOI":"10.4065\/75.9.933","volume":"75","year":"2000","journal-title":"Mayo Clin Proc"},{"key":"R41","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0002-8223(97)00044-8","volume":"97","year":"1997","journal-title":"J Am Diet Assoc"},{"key":"R42","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1097\/00004714-200108000-00001","volume":"21","year":"2001","journal-title":"J Clin Psychopharmacol"},{"key":"R43","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1001\/jama.1995.03530130055028","volume":"274","year":"1995","journal-title":"JAMA"},{"key":"R44","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/00043798-199808000-00004","volume":"5","year":"1998","journal-title":"J Cardiovasc Risk"},{"key":"R45","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1146\/annurev.med.49.1.31","volume":"49","year":"1998","journal-title":"Annu Rev Medicine"},{"key":"R46","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1001\/jama.1993.03510220049033","volume":"270","year":"1993","journal-title":"JAMA"},{"key":"R47","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/labinvest.3780275","volume":"81","year":"2001","journal-title":"Lab Invest"},{"key":"R48","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1136\/bmj.316.7135.894","volume":"316","year":"1998","journal-title":"BMJ"},{"key":"R49","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1093\/ajcn\/69.1.99","volume":"69","year":"1999","journal-title":"Am J Clin Nutr"},{"key":"R50","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1161\/01.CIR.98.23.2520","volume":"98","year":"1998","journal-title":"Circulation"},{"key":"R51","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0021-9150(97)00237-2","volume":"136","year":"1998","journal-title":"Atherosclerosis"},{"key":"R52","doi-asserted-by":"crossref","first-page":"363","DOI":"10.7326\/0003-4819-131-5-199909070-00008","volume":"131","year":"1999","journal-title":"Ann Intern Med"},{"key":"R53","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S0002-8223(02)90281-6","volume":"102","year":"2002","journal-title":"J Am Diet Assoc"},{"key":"R54","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1093\/jn\/130.2.129","volume":"130","year":"2000","journal-title":"J Nutr"},{"key":"R55","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1093\/jn\/128.7.1204","volume":"128","year":"1998","journal-title":"J Nutr"},{"key":"R56","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1093\/ajcn\/72.4.998","volume":"72","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"R57","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/jnci\/85.11.875","volume":"85","year":"1993","journal-title":"J Natl Cancer Inst"},{"key":"R58","doi-asserted-by":"crossref","first-page":"517","DOI":"10.7326\/0003-4819-129-7-199810010-00002","volume":"129","year":"1998","journal-title":"Ann Intern Med"},{"key":"R59","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S1047-2797(00)00188-5","volume":"11","year":"2001","journal-title":"Ann Epidemiol"},{"key":"R60","first-page":"1098","volume":"57","year":"1997","journal-title":"Cancer Res"},{"key":"R61","doi-asserted-by":"crossref","first-page":"12810","DOI":"10.1073\/pnas.96.22.12810","volume":"96","year":"1999","journal-title":"PNAS"},{"key":"R62","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1001\/jama.1992.03480040076034","volume":"267","year":"1992","journal-title":"JAMA"},{"key":"R63","first-page":"526","volume":"18","year":"1997","journal-title":"Eur J Gynaec Oncol"},{"key":"R64","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1001\/jama.281.17.1632","volume":"281","year":"1999","journal-title":"JAMA"},{"key":"R65","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1097\/00001648-200107000-00012","volume":"12","year":"2001","journal-title":"Epidemiology"},{"key":"R66","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1093\/jnci\/92.3.266","volume":"92","year":"2000","journal-title":"J Natl Cancer Inst"},{"key":"R67","doi-asserted-by":"crossref","first-page":"614S","DOI":"10.1093\/ajcn\/71.2.614s","volume":"71","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"R68","doi-asserted-by":"crossref","first-page":"2917","DOI":"10.1001\/jama.1983.03330450047024","volume":"249","year":"1983","journal-title":"JAMA"},{"key":"R69","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/00000441-198907000-00004","volume":"298","year":"1989","journal-title":"Am J Med Sci"},{"key":"R70","first-page":"475","volume":"87","year":"1993","journal-title":"Acta Neurol Scand"},{"key":"R71","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1111\/j.1365-2362.1996.tb02129.x","volume":"26","year":"1996","journal-title":"Eur J Clin Invest"},{"key":"R72","first-page":"1992","volume":"126","year":"1996","journal-title":"J Nutr"},{"key":"R73","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1093\/ajcn\/63.3.306","volume":"63","year":"1996","journal-title":"Am J Clin Nutr"},{"key":"R74","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1093\/ajcn\/65.1.20","volume":"65","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"R75","first-page":"M76","volume":"52","year":"1997","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R76","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1001\/archneur.55.11.1449","volume":"55","year":"1998","journal-title":"Arch Neurol"},{"key":"R77","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1056\/NEJM198806303182604","volume":"318","year":"1988","journal-title":"N Engl J Med"},{"key":"R78","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1600-0447.1992.tb03285.x","volume":"86","year":"1992","journal-title":"Acta Psychiatr Scand"},{"key":"R79","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1093\/ajcn\/71.4.993","volume":"71","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"R80","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1056\/NEJMoa011613","volume":"346","year":"2002","journal-title":"N Engl J Med"},{"key":"R81","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1093\/ajcn\/75.5.908","volume":"75","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"R82","first-page":"1188","volume":"56","year":"2001","journal-title":"Neurology"},{"key":"R83","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1093\/ajcn\/73.5.927","volume":"73","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"R84","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1093\/ajcn\/66.4.741","volume":"66","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"R85","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/S0002-8223(96)00273-8","volume":"96","year":"1996","journal-title":"J Am Diet Assoc"},{"key":"R86","unstructured":"World Cancer Research Fund:\u201cFood, Nutrition and the Prevention of Cancer: A global perspective.\u201d Washington, DC: American Institute for Cancer Research,1997 ."},{"key":"R88","unstructured":"US Department of Health and Human Services:\u201cDietary Guidelines for Americans,\u201d 5th ed. Home and Garden Bulletin No. 232. Washington DC: US Department of Health and Human Services,2000 ."}],"container-title":["Journal of the American College of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07315724.2003.10719270","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T18:14:49Z","timestamp":1563214489000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/07315724.2003.10719270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,2]]},"references-count":86,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,2]]}},"alternative-id":["10.1080\/07315724.2003.10719270"],"URL":"https:\/\/doi.org\/10.1080\/07315724.2003.10719270","relation":{},"ISSN":["0731-5724","1541-1087"],"issn-type":[{"value":"0731-5724","type":"print"},{"value":"1541-1087","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,2]]}}}