{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T17:52:09Z","timestamp":1789235529476,"version":"build-2803163510"},"reference-count":63,"publisher":"Informa UK Limited","issue":"7","funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P01CA124570"],"award-info":[{"award-number":["P01CA124570"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["NINDS U54NS092090"],"award-info":[{"award-number":["NINDS U54NS092090"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["U54NS092090"],"award-info":[{"award-number":["U54NS092090"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ohio Supercomputing Center","award":["PCCF0020"],"award-info":[{"award-number":["PCCF0020"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biomolecular Structure and Dynamics"],"published-print":{"date-parts":[[2019,5,3]]},"DOI":"10.1080\/07391102.2018.1465854","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T10:13:30Z","timestamp":1523960010000},"page":"1766-1782","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":47,"title":["Dynamics and structural stability effects of germline <i>PTEN<\/i> mutations associated with cancer versus autism phenotypes"],"prefix":"10.1080","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5560-8871","authenticated-orcid":false,"given":"Iris Nira","family":"Smith","sequence":"first","affiliation":[{"name":"Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic , Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6050-409X","authenticated-orcid":false,"given":"Stetson","family":"Thacker","sequence":"additional","affiliation":[{"name":"Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic , Cleveland, OH, USA"},{"name":"Cleveland Clinic Lerner College of Medicine , Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritika","family":"Jaini","sequence":"additional","affiliation":[{"name":"Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic , Cleveland, OH, USA"},{"name":"Germline High Risk Cancer Focus Group, Comprehensive Cancer Center, Case Western Reserve University School of Medicine , Cleveland, OH, USA"},{"name":"Cleveland Clinic Lerner College of Medicine , Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3693-5145","authenticated-orcid":false,"given":"Charis","family":"Eng","sequence":"additional","affiliation":[{"name":"Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic , Cleveland, OH, USA"},{"name":"Taussig Cancer Institute, Cleveland Clinic , Cleveland, OH, USA"},{"name":"Department of Genetics and Genome Sciences, Case Westren Reserve University School of Medicine , Cleveland, OH, USA"},{"name":"Germline High Risk Cancer Focus Group, Comprehensive Cancer Center, Case Western Reserve University School of Medicine , Cleveland, OH, USA"},{"name":"Cleveland Clinic Lerner College of Medicine , Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2018,5,14]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2016.1229634"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2013.855144"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-015-7658-1_21"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1063\/1.448118"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2004.024646"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1002\/prot.24748"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-9-S2-S6"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2010.05.009"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1063\/1.464397"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0932835100"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.37.11.828"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1002\/humu.10257"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv343"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003569"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2014.125"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2011.09.021"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4001896"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1177\/1947601911407325"},{"issue":"24","key":"CIT0019","first-page":"7033","volume":"60","author":"Georgescu M. M.","year":"2000","journal-title":"Cancer Research"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)01963-3"},{"issue":"12","key":"CIT0021","first-page":"3147","volume":"60","author":"Han S. Y.","year":"2000","journal-title":"Cancer Research"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1002\/pro.2664"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-3811"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1002\/(Sici)1096-987x(199709)18:12<1463::Aid-Jcc4>3.0.Co;2-H"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1016\/0263-7855(96)00018-5"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.5b00028"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6947-11-51"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1002\/humu.21242"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2016.1199329"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81663-3"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2016.01.030"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1126\/science.275.5308.1943"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.22.13375"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/S0962-8924(99)01519-6"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.70.1.247"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/7.3.507"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1038\/ng0897-333"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/8.8.1461"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btn353"},{"issue":"12","key":"CIT0040","first-page":"2500","volume":"58","author":"Maxwell G. L.","year":"1998","journal-title":"Cancer Research"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1002\/aur.132"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2016.1190299"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.17.9052"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20090"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr337"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw1000"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.2142\/biophysico.14.0_85"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1002\/prot.25105"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2014-102803"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1038\/ng0497-356"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2013.07.014"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2017.1404934"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/91.21.1820"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2010.11.013"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31364"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2016.1166456"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2017.1407675"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20291"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1086\/340026"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.26.15587"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2007.01.021"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2013.770372"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2017.07.12"}],"container-title":["Journal of Biomolecular Structure and Dynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07391102.2018.1465854","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T01:28:32Z","timestamp":1599442112000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07391102.2018.1465854"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,14]]},"references-count":63,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,5,3]]}},"alternative-id":["10.1080\/07391102.2018.1465854"],"URL":"https:\/\/doi.org\/10.1080\/07391102.2018.1465854","relation":{},"ISSN":["0739-1102","1538-0254"],"issn-type":[{"value":"0739-1102","type":"print"},{"value":"1538-0254","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,14]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbsd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbsd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2018-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}