{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:41:22Z","timestamp":1787006482788,"version":"build-2736575974"},"reference-count":74,"publisher":"Informa UK Limited","issue":"22","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biomolecular Structure and Dynamics"],"published-print":{"date-parts":[[2023,12,29]]},"DOI":"10.1080\/07391102.2023.2191137","type":"journal-article","created":{"date-parts":[[2023,3,19]],"date-time":"2023-03-19T20:43:21Z","timestamp":1679258601000},"page":"12464-12479","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":13,"title":["MERS virus spike protein HTL-epitopes selection and multi-epitope vaccine design using computational biology"],"prefix":"10.1080","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8287-8375","authenticated-orcid":false,"given":"Amit","family":"Joshi","sequence":"first","affiliation":[{"name":"Department of Biotechnology, Invertis University, Bareilly, Uttar Pradesh, India"},{"name":"Department of Biochemistry, Kalinga University, Raipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8286-3736","authenticated-orcid":false,"given":"Nahid","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Genetic Engineering, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8638-4217","authenticated-orcid":false,"given":"Neeta Raj","family":"Sharma","sequence":"additional","affiliation":[{"name":"Domain of Bioinformatics, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2349-1220","authenticated-orcid":false,"given":"Vikas","family":"Kaushik","sequence":"additional","affiliation":[{"name":"Domain of Bioinformatics, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6752-4296","authenticated-orcid":false,"given":"Subhomoi","family":"Borkotoky","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Invertis University, Bareilly, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,3,19]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky356"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2020.1770127"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40794-021-00147-1"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2021.116586"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2016.04.005"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-801238-3.11488-6"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac456"},{"issue":"4","key":"e_1_3_5_9_1","first-page":"102","article-title":"Infection with Middle East respiratory syndrome coronavirus","volume":"51","author":"Alsolamy S.","year":"2015","unstructured":"Alsolamy, S., & Arabi, Y. M. (2015). Infection with Middle East respiratory syndrome coronavirus. Canadian Journal of Respiratory Therapy, 51(4), 102. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26566382","journal-title":"Canadian Journal of Respiratory Therapy,"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-80899-6"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cplett.2021.138446"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(21)00193-2"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz297"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/842329"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1519235113"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01176-20"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41426-018-0056-7"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2022.2021882"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-021-10356-z"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13099-022-00495-z"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2021.105171"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/263952"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6150-8-30"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt619"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-8-4"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30160-2"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1385\/1-59259-890-0:571"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0142563"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki376"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073957"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/ct100747y"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43141-021-00220-4"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imu.2020.100338"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-67749-1"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-814039-0.00003-5"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-16954-7"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens8040220"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2020.104728"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.05.022"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.06.20.449146"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp386"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2022.04.043"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-92176-1"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.69273"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.90.075503"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)33221-0"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2020.107051"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac446"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-022-10382-5"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103160"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20084"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu097"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.2147\/AABC.S366431"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009862"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa379"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6605e1"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43042-022-00224-w"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2020.10.016"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/prot.21078"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/2680160"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/0471250953.bi0313s48"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5SC03892H"},{"key":"e_1_3_5_63_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S175114"},{"key":"e_1_3_5_64_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-019-2116-8"},{"key":"e_1_3_5_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20291"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab1061"},{"key":"e_1_3_5_67_1","unstructured":"WHO. (2019). Middle East respiratory syndrome coronavirus (MERS-CoV). https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/middle-east-respiratory-syndrome-coronavirus-(mers-cov)"},{"key":"e_1_3_5_68_1","unstructured":"WHO. (2022). MERS outbreaks. World Health Organization - Regional Office for the Eastern Mediterranean. http:\/\/www.emro.who.int\/health-topics\/mers-cov\/mers-outbreaks.html"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.3390\/v11030280"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm290"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-81749-9"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3213"},{"key":"e_1_3_5_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2014.11.013"},{"key":"e_1_3_5_74_1","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2018.1506702"},{"key":"e_1_3_5_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2021.11.015"}],"container-title":["Journal of Biomolecular Structure and Dynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07391102.2023.2191137","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T13:37:55Z","timestamp":1709645875000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07391102.2023.2191137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,19]]},"references-count":74,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2023,12,29]]}},"alternative-id":["10.1080\/07391102.2023.2191137"],"URL":"https:\/\/doi.org\/10.1080\/07391102.2023.2191137","relation":{},"ISSN":["0739-1102","1538-0254"],"issn-type":[{"value":"0739-1102","type":"print"},{"value":"1538-0254","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,19]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbsd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbsd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2022-07-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}