{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:22:23Z","timestamp":1792160543334,"version":"4.4.0"},"reference-count":123,"publisher":"Informa UK Limited","issue":"22","funder":[{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biomolecular Structure and Dynamics"],"published-print":{"date-parts":[[2024,12,13]]},"DOI":"10.1080\/07391102.2023.2268173","type":"journal-article","created":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T16:08:41Z","timestamp":1698509321000},"page":"12105-12121","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":8,"title":["Computational exploration and design of a multi-epitopes vaccine construct against\n            <i>Chlamydia psittaci<\/i>"],"prefix":"10.1080","volume":"42","author":[{"given":"Amal M.","family":"Alsubaiyel","sequence":"first","affiliation":[{"name":"Department of Pharmaceutics, College of Pharmacy, Qassim University, Buraydah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah I.","family":"Bukhari","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,10,28]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00268"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/6325568"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10050691"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10030462"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-10364-z"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins7030974"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1647\/217-265"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-021-00465-4"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.1.235"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1086\/315630"},{"key":"e_1_3_4_12_1","unstructured":"Butler J. C. & Whitney C. G. (1998). Compendium of measures to control Chlamydia psittaci infection among humans (Psittacosis) and pet birds (Avian chlamydiosis)."},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp0536192"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/v12040445"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1086\/322044"},{"key":"e_1_3_4_16_1","unstructured":"Castiglione F. & Bernaschi M. (2004). C-immsim: Playing with the immune response. Proceedings of the Sixteenth International Symposium on Mathematical Theory of Networks and Systems (MTNS2004)."},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.12.980"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep24373"},{"issue":"13","key":"e_1_3_4_19_1","first-page":"5345","article-title":"Testing RPGR specific ribozyme and siRNA in\u00a0vitro: Tools for the treatment of dominant X-linked retinitis pigmentosa","volume":"49","author":"Chen B.","year":"2008","unstructured":"Chen, B., O\u2019Donoghue, M. B., Lewin, A. S., & Gorbatyuk, M. S. (2008). Testing RPGR specific ribozyme and siRNA in\u00a0vitro: Tools for the treatment of dominant X-linked retinitis pigmentosa. Investigative Ophthalmology\\& Visual Science, 49(13), 5345.","journal-title":"Investigative Ophthalmology\\& Visual Science,"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40249-020-00713-3"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki008"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2011.09.013"},{"key":"e_1_3_4_23_1","volume-title":"Computational analysis of the immunogenicity and sequence diversity of Mycobacterium tuberculosis PPE\\_MPTR proteins","author":"Colic A.","year":"2017","unstructured":"Colic, A. (2017). Computational analysis of the immunogenicity and sequence diversity of Mycobacterium tuberculosis PPE\\_MPTR proteins. Stellenbosch University."},{"key":"e_1_3_4_24_1","doi-asserted-by":"crossref","unstructured":"Deb D. Basak S. Kar T. Narsaria U. Castiglione F. Paul A. Pandey A. & Srivastava A. P. (2020). A candidate multi-epitope vaccine against pathogenic Chandipura a Identified using Immunoinformatics.","DOI":"10.21203\/rs.3.rs-56434\/v1"},{"issue":"11","key":"e_1_3_4_25_1","first-page":"75","article-title":"TLR4 in Chlamydia trachomatis infections: Knockout mice, STD patients and women with tubal factor subfertility","volume":"45","author":"Den Hartog J. E.","year":"2009","unstructured":"Den Hartog, J. E., Lyons, J. M., Ouburg, S., Fennema, J. S. A., De Vries, H. J. C., Bruggeman, C. A., Ito, J. I., Pena, A. S., Land, J. A., & Morre, S. A. (2009). TLR4 in Chlamydia trachomatis infections: Knockout mice, STD patients and women with tubal factor subfertility. Drugs of Today (Barcelona, Spain: 1998), 45 Suppl B(11), 75\u201382.","journal-title":"Drugs of Today (Barcelona, Spain: 1998)"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.5455\/javar.2021.h481"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2022.2021882"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13099-022-00495-z"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00894-014-2278-5"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.01784"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-8-4"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.2174\/1875035400801010022"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2010.01.001"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/bfgp\/ely020"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2016.107"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bti057"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.6026\/97320630012074"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.9.5597-5605.2001"},{"key":"e_1_3_4_39_1","unstructured":"Gladwin M. Trattler W. & Mahan C. S. (2004). Clinical microbiology."},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/prot.10547"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.2165\/00822942-200605010-00008"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10020189"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-2285-7_7"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12033-020-00266-8"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2008.09.046"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.12-07-02865.1992"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410x(93)90039-z"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/13.4.425"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq003"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2020.1761883"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43141-022-00324-5"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13721-021-00339-x"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2019.1711057"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43141-021-00160-z"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2019.103937"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23071550"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki001"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmic.2008.03.005"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz288"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.7774\/cevr.2020.9.1.15"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines2030515"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/prot.22711"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab1107"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/356083a0"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2022.113325"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2021.09.025"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2022.04.043"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens12030376"},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2020.1811091"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2021.1883111"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1145\/2629691"},{"key":"e_1_3_4_72_1","volume-title":"Mahboob Ul and Sanami, Samira and Ahmad, Sajjad and Khan, Saifullah and Al-Harbi, Alhanouf I. and Abideen, Syed Ainul and Irfan, Muhammad and Afsheen, Zobia and Khurram, Muhammad, Proteome Wide Screening of Potential Vaccine Targets Against Brucella Melit","author":"Malik M.","unstructured":"Malik, M., Ullah, A., Sanami, S., Ahmad, S., Khan, S., Al-Harbi, A. I., Abideen, S. A., Irfan, M., Afsheen, Z., & Khurram, M. (n.d.). Proteome Wide Screening of a Vaccine Targets Against Brucella Melitensis. In Mahboob Ul and Sanami, Samira and Ahmad, Sajjad and Khan, Saifullah and Al-Harbi, Alhanouf I. and Abideen, Syed Ainul and Irfan, Muhammad and Afsheen, Zobia and Khurram, Muhammad, Proteome Wide Screening of Potential Vaccine Targets Against Brucella Melit."},{"issue":"2","key":"e_1_3_4_73_1","first-page":"208","article-title":"Impact of the immune system and immunotherapy in colorectal cancer","volume":"6","author":"Markman J. L.","year":"2015","unstructured":"Markman, J. L., & Shiao, S. L. (2015). Impact of the immune system and immunotherapy in colorectal cancer. Journal of Gastrointestinal Oncology, 6(2), 208.","journal-title":"Journal of Gastrointestinal Oncology,"},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.2174\/092986609788681788"},{"key":"e_1_3_4_75_1","doi-asserted-by":"publisher","DOI":"10.1021\/ct300418h"},{"key":"e_1_3_4_76_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/17.7.646"},{"key":"e_1_3_4_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2021.04.014"},{"key":"e_1_3_4_78_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-021-03188-y"},{"key":"e_1_3_4_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2021.105120"},{"key":"e_1_3_4_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2022.105507"},{"key":"e_1_3_4_81_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-12651-1"},{"issue":"6","key":"e_1_3_4_82_1","first-page":"9679","article-title":"In-silico analysis and molecular dynamics simulations of lysozyme by GROMACS 2020.2. Annals of the Romanian Society for.","volume":"25","author":"Panwar A.","year":"2021","unstructured":"Panwar, A., & Kumar, A. (2021). In-silico analysis and molecular dynamics simulations of lysozyme by GROMACS 2020.2. Annals of the Romanian Society for. Cell Biology, 25(6), 9679\u20139685.","journal-title":"Cell Biology,"},{"key":"e_1_3_4_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41385-019-0217-6"},{"key":"e_1_3_4_84_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18115723"},{"key":"e_1_3_4_85_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.470043"},{"key":"e_1_3_4_86_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm219"},{"key":"e_1_3_4_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41597-020-0555-y"},{"key":"e_1_3_4_88_1","doi-asserted-by":"publisher","DOI":"10.47059\/revistageintec.v11i1.1688"},{"key":"e_1_3_4_89_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-020-04537-2"},{"key":"e_1_3_4_90_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr335"},{"key":"e_1_3_4_91_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-021-02859-0"},{"key":"e_1_3_4_92_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612823666170913163904"},{"key":"e_1_3_4_93_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19148408"},{"key":"e_1_3_4_94_1","doi-asserted-by":"publisher","DOI":"10.1021\/ct400341p"},{"key":"e_1_3_4_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2019.04.030"},{"key":"e_1_3_4_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2020.10.016"},{"key":"e_1_3_4_97_1","first-page":"8","article-title":"The reverse vaccinology-A contextual overview","volume":"2","author":"Santos A.","year":"2011","unstructured":"Santos, A., Ali, A., Barbosa, E., Silva, A., Miyoshi, A., Barh, D., & Azevedo, V. (2011). The reverse vaccinology-A contextual overview. IIOABJ, 2, 8\u201315.","journal-title":"IIOABJ,"},{"key":"e_1_3_4_98_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki481"},{"key":"e_1_3_4_99_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-021-06205-5"},{"key":"e_1_3_4_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-020-0737-y"},{"key":"e_1_3_4_101_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.226.532"},{"key":"e_1_3_4_102_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1718341115"},{"key":"e_1_3_4_103_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines3030579"},{"key":"e_1_3_4_104_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198407000-00004"},{"key":"e_1_3_4_105_1","doi-asserted-by":"publisher","DOI":"10.1080\/01490451.2021.1992042"},{"key":"e_1_3_4_106_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-64952-y"},{"key":"e_1_3_4_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2009.04.001"},{"key":"e_1_3_4_108_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1657"},{"key":"e_1_3_4_109_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19095568"},{"key":"e_1_3_4_110_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph182010961"},{"key":"e_1_3_4_111_1","doi-asserted-by":"publisher","DOI":"10.1089\/vim.2011.0051"},{"key":"e_1_3_4_112_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.199009921"},{"key":"e_1_3_4_113_1","doi-asserted-by":"publisher","DOI":"10.1108\/AGJSR-11-2022-0274"},{"key":"e_1_3_4_114_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/27.4.919"},{"key":"e_1_3_4_115_1","doi-asserted-by":"publisher","DOI":"10.1089\/omi.2015.0105"},{"key":"e_1_3_4_116_1","doi-asserted-by":"publisher","DOI":"10.1086\/428290"},{"key":"e_1_3_4_117_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm290"},{"key":"e_1_3_4_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(84)90412-4"},{"key":"e_1_3_4_119_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2012.2142"},{"key":"e_1_3_4_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.provac.2009.07.005"},{"key":"e_1_3_4_121_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-01699-z"},{"key":"e_1_3_4_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiolchem.2020.107209"},{"key":"e_1_3_4_123_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq249"},{"key":"e_1_3_4_124_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41596-022-00728-0"}],"container-title":["Journal of Biomolecular Structure and Dynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07391102.2023.2268173","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T12:18:16Z","timestamp":1732191496000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07391102.2023.2268173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,28]]},"references-count":123,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2024,12,13]]}},"alternative-id":["10.1080\/07391102.2023.2268173"],"URL":"https:\/\/doi.org\/10.1080\/07391102.2023.2268173","relation":{},"ISSN":["0739-1102","1538-0254"],"issn-type":[{"value":"0739-1102","type":"print"},{"value":"1538-0254","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,28]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbsd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbsd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2023-07-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}