{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T01:16:18Z","timestamp":1784510178193,"version":"3.55.0"},"reference-count":72,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biomolecular Structure and Dynamics"],"published-print":{"date-parts":[[2025,4,13]]},"DOI":"10.1080\/07391102.2023.2297010","type":"journal-article","created":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T14:03:41Z","timestamp":1703685821000},"page":"3116-3129","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":6,"title":["Annonaceous acetogenins as promising DNA methylation inhibitors to prevent and treat leukemogenesis \u2013 an\n            <i>in silico<\/i>\n            approach"],"prefix":"10.1080","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8726-699X","authenticated-orcid":false,"given":"Udayadharshini","family":"Subaramaniyam","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women","place":["Coimbatore, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6875-8141","authenticated-orcid":false,"given":"Divya","family":"Ramalingam","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women","place":["Coimbatore, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6590-1262","authenticated-orcid":false,"given":"Ranjini","family":"Balan","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women","place":["Coimbatore, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5285-6578","authenticated-orcid":false,"given":"Biswaranjan","family":"Paital","sequence":"additional","affiliation":[{"name":"Redox Regulation Laboratory, Department of Zoology, College of Basic Science and Humanities, Odisha University of Agriculture and Technology","place":["Bhubaneswar, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1060-9157","authenticated-orcid":false,"given":"Pranati","family":"Sar","sequence":"additional","affiliation":[{"name":"Biotechnology Department, Silver Oak Institute of Science, Silver Oak University","place":["Ahmedabad, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirmaladevi","family":"Ramalingam","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women","place":["Coimbatore, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,12,27]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms7090296"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S103216"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.928884"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.26975"},{"key":"e_1_3_3_6_1","unstructured":"Biswal P. Rai N. & Sharma K. D. (2013). Molecular dynamics study of TIP3P SPC\/E and TIP4P water models at room temperature [Doctoral dissertation]. http:\/\/ethesis.nitrkl.ac.in\/5361\/1\/411CY2031.pdf"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jphp.13182"},{"key":"e_1_3_3_8_1","unstructured":"Cheminformatics M. (2011). Calculation of molecular properties and bioactivity score. http:\/\/www.molinspiration.com\/cgi-bin\/properties."},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07399-0"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep42717"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2022.121636"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.teler.2023.100065"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-018-0070-8"},{"key":"e_1_3_3_14_1","unstructured":"Desmond Molecular Dynamics System D. E. Shaw Research. (2023). Maestro-Desmond Interoperability Tools. Schr\u00f6dinger."},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku401"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26102926"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11468-020-01334-0"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbx045"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbior.2019.100665"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0275432"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25204861"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1159\/000452091"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cancergen.2021.07.004"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.2741\/4847"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14184539"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.2741\/S524"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.00783"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1159\/000447076"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sintl.2022.100180"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmgm.2017.05.014"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.2741\/4809"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-32509-4"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25061375"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2020.108963"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.1c00302"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2015.05.001"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24076311"},{"key":"e_1_3_3_38_1","unstructured":"Maestro. (2023). Schr\u00f6dinger LLC."},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2021.2013321"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2022.104757"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2011.02.003"},{"key":"e_1_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2019.103451"},{"key":"e_1_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42485-019-00025-7"},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-43320-5"},{"key":"e_1_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2021.1970624"},{"key":"e_1_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13596-020-00517-8"},{"key":"e_1_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1088\/1757-899X\/736\/6\/062011"},{"key":"e_1_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2013-14-9-r105"},{"key":"e_1_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43094-021-00198-3"},{"key":"e_1_3_3_50_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.8b00890"},{"key":"e_1_3_3_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12551-016-0247-1"},{"key":"e_1_3_3_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12539-013-0150-4"},{"key":"e_1_3_3_53_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1194794"},{"key":"e_1_3_3_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmr.2554"},{"issue":"3","key":"e_1_3_3_55_1","first-page":"172","article-title":"Patterns of DNMT1 promoter methylation in patients with acute lymphoblastic leukemia","volume":"11","author":"Rahmani T.","year":"2017","unstructured":"Rahmani, T., Azad, M., Chahardouli, B., Nasiri, H., Vatanmakanian, M., & Kaviani, S. (2017). Patterns of DNMT1 promoter methylation in patients with acute lymphoblastic leukemia. International Journal of Hematology-Oncology and Stem Cell Research, 11(3), 172.","journal-title":"International Journal of Hematology-Oncology and Stem Cell Research,"},{"key":"e_1_3_3_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hermed.2018.04.004"},{"key":"e_1_3_3_57_1","doi-asserted-by":"publisher","DOI":"10.52586\/j.fbl2701010"},{"key":"e_1_3_3_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-16-0666-3_35"},{"key":"e_1_3_3_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05769-2"},{"key":"e_1_3_3_60_1","doi-asserted-by":"publisher","DOI":"10.14670\/HH-11-976"},{"key":"e_1_3_3_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2015.03.022"},{"key":"e_1_3_3_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2021.05.004"},{"key":"e_1_3_3_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.01.021"},{"key":"e_1_3_3_64_1","doi-asserted-by":"publisher","DOI":"10.33263\/BRIAC114.1138011389"},{"key":"e_1_3_3_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201700582"},{"key":"e_1_3_3_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.acr.2021.03.007"},{"key":"e_1_3_3_67_1","volume-title":"Jaguar, and glide","author":"Wizard P. P.","year":"2009","unstructured":"Wizard, P. P., Maestro, M., & Phase, I. F. (2009). Jaguar, and glide. Schrodinger, LLC."},{"key":"e_1_3_3_68_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty707"},{"key":"e_1_3_3_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-398312-1.00008-1"},{"key":"e_1_3_3_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2022.104757"},{"key":"e_1_3_3_71_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx2003849"},{"key":"e_1_3_3_72_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.103520"},{"key":"e_1_3_3_73_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms221910693"}],"container-title":["Journal of Biomolecular Structure and Dynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07391102.2023.2297010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T11:55:49Z","timestamp":1739879749000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07391102.2023.2297010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,27]]},"references-count":72,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,4,13]]}},"alternative-id":["10.1080\/07391102.2023.2297010"],"URL":"https:\/\/doi.org\/10.1080\/07391102.2023.2297010","relation":{},"ISSN":["0739-1102","1538-0254"],"issn-type":[{"value":"0739-1102","type":"print"},{"value":"1538-0254","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,27]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbsd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbsd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2023-09-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}