{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T06:53:50Z","timestamp":1780556030935,"version":"3.54.1"},"reference-count":68,"publisher":"Informa UK Limited","issue":"3-4","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2020,5,18]]},"DOI":"10.1080\/07853890.2020.1744708","type":"journal-article","created":{"date-parts":[[2020,3,26]],"date-time":"2020-03-26T11:59:35Z","timestamp":1585223975000},"page":"94-108","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":10,"title":["Associations of serum sclerostin with bone mineral density, markers of bone metabolism and thalassaemia characteristics in adult patients with transfusion-dependent beta-thalassaemia"],"prefix":"10.1080","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9892-7979","authenticated-orcid":false,"given":"Katya","family":"Sapunarova","sequence":"first","affiliation":[{"name":"First Department of Internal Medicine, Department of Hematology, Medical University, Plovdiv, Bulgaria;"},{"name":"Clinic of Clinical Hematology, University Hospital \u201cSv. Georgi\u201d, Plovdiv, Bulgaria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vesselina","family":"Goranova-Marinova","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Department of Hematology, Medical University, Plovdiv, Bulgaria;"},{"name":"Clinic of Clinical Hematology, University Hospital \u201cSv. Georgi\u201d, Plovdiv, Bulgaria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pencho","family":"Georgiev","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Department of Hematology, Medical University, Plovdiv, Bulgaria;"},{"name":"Clinic of Clinical Hematology, University Hospital \u201cSv. Georgi\u201d, Plovdiv, Bulgaria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"Deneva","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, University Hospital \u201cSv. Georgi\u201d, Plovdiv, Bulgaria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Tsvetkova","sequence":"additional","affiliation":[{"name":"Department of Imaging Diagnostics, Medical University, Plovdiv, Bulgaria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanet","family":"Grudeva-Popova","sequence":"additional","affiliation":[{"name":"Clinic of Clinical Hematology, University Hospital \u201cSv. Georgi\u201d, Plovdiv, Bulgaria;"},{"name":"Department of Medical Oncology, University Hospital \u201cSv. Georgi\u201d, Plovdiv, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,3,26]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2017.1.272"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-0270"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra067395"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2013.154"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1586\/eem.09.38"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-010-9372-1"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.4274\/jcrpe.galenos.2018.2018.0074"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1312618"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1007\/s00774-015-0689-8"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1334.010"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.2081"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2012.09.016"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2013.02.022"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2016.10.007"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1402.075"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00982.2007"},{"key":"CIT0017","doi-asserted-by":"crossref","unstructured":"Chang M, Kramer I, Huber T, et\u00a0al. Disruption of Lrp4 function by genetic deletion or pharmacological blockade increases bone mass and serum sclerostin levels. PNAS PLUS | Published online November 17, 2014; [cited 2020 Mar 19]. Available from: http:\/\/www.pnas.org\/cgi\/doi\/10.1073\/pnas.1413828111.","DOI":"10.1073\/pnas.1413828111"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2011.12.048"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2016.71"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.24537"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.081206"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2011.540565"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.173"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2014.04.016"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.20.010403.113126"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.4161\/org.4.2.5851"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1080\/07435800.2017.1373662"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-2186"},{"issue":"13","key":"CIT0029","first-page":"2480","volume":"126","author":"Xu X","year":"2013","journal-title":"Clin Med J (Engl)"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1177\/1721727X1301100204"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aac4351"},{"key":"CIT0032","first-page":"9295313","volume":"2017","author":"Jianfeng S","year":"2017","journal-title":"BioMed Research Int"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V116.21.2963.2963"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-11913-7"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.125543"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-017-4104-2"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-10-3982"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.2174\/1566524019666190314114447"},{"issue":"4","key":"CIT0039","first-page":"288","volume":"5","author":"Moinzadeh L","year":"2018","journal-title":"Int. J. of Medical Laboratory"},{"key":"CIT0040","unstructured":"World Health Organization. 1994. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: report of a WHO study group [meeting held in Rome from 22 to 25 June 1992]. World Health Organization; [cited 2020 MAr 19]. Available from: https:\/\/apps.who.int\/iris\/handle\/10665\/39142."},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2000.15.4.721"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1007\/s40610-016-0040-8"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20102555"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2016.11.024"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.11005\/jbm.2014.21.1.69"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2845"},{"issue":"2","key":"CIT0047","first-page":"167","volume":"62","author":"Holdsworth G","year":"2019","journal-title":"JME"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.040113"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/320737"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-3249"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.128"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00033.2015"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2016.12.004"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-2283"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2018.02.028"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025900"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-014-2808-0"},{"issue":"1","key":"CIT0058","first-page":"17","volume":"51","author":"Pietrapertosa AC","year":"2009","journal-title":"Panminerva Med"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80209-3"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.5798\/diclemedj.0921.2012.04.0186"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.044370"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-017-0820-1"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000236428.91125.e6"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1177\/1721727X1301100204"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2004.12.025"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2009.06.002"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2008.000893"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2018023085"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2020.1744708","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,17]],"date-time":"2021-04-17T02:04:32Z","timestamp":1618625072000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2020.1744708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,26]]},"references-count":68,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2020,5,18]]}},"alternative-id":["10.1080\/07853890.2020.1744708"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2020.1744708","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,26]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-23","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}