{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T14:52:22Z","timestamp":1785855142073,"version":"3.56.0"},"reference-count":43,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Institute of Bioresources and Sustainable Development, Dept of Biotechnology (DBT), Government of India"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1080\/07853890.2021.1995625","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T08:28:35Z","timestamp":1636446515000},"page":"2009-2017","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":12,"title":["Synergistic effect of ursolic acid and piperine in CCl\n            <sub>4<\/sub>\n            induced hepatotoxicity"],"prefix":"10.1080","volume":"53","author":[{"given":"Sayan","family":"Biswas","sequence":"first","affiliation":[{"name":"School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University","place":["Kolkata, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Kar","sequence":"additional","affiliation":[{"name":"School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University","place":["Kolkata, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanaocha","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Institute of Bioresources and Sustainable Development","place":["Imphal, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pallab K.","family":"Haldar","sequence":"additional","affiliation":[{"name":"School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University","place":["Kolkata, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pulok K.","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University","place":["Kolkata, India"]},{"name":"Department of Biotechnology, Institute of Bioresources and Sustainable Development","place":["Imphal, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"key":"e_1_3_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2014.03.023"},{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2010.09.022"},{"key":"e_1_3_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.synres.2016.12.001"},{"key":"e_1_3_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-800874-4.00001-5"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.synres.2018.10.003"},{"key":"e_1_3_6_7_1","first-page":"660","volume-title":"Safety-Related quality issues for the development of herbal drugs in: quality control and evaluation of herbal drugs","author":"Mukherjee PK.","year":"2020","unstructured":"Mukherjee PK. 2020. Safety-Related quality issues for the development of herbal drugs in: quality control and evaluation of herbal drugs. Amsterdam (The Netherlands): Elsevier, p. 660\u2013664."},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111673"},{"key":"e_1_3_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fshw.2021.04.016"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i40.14787"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2221-1691(15)30159-3"},{"key":"e_1_3_6_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.00509"},{"key":"e_1_3_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12523"},{"key":"e_1_3_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2017.10.028"},{"key":"e_1_3_6_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408347.2017.1390425"},{"key":"e_1_3_6_16_1","doi-asserted-by":"publisher","DOI":"10.1517\/13543776.2016.1118057"},{"key":"e_1_3_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2013.08.007"},{"key":"e_1_3_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.05.026"},{"key":"e_1_3_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1995-7645(11)60011-4"},{"key":"e_1_3_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2006.12.027"},{"key":"e_1_3_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2015.07.029"},{"key":"e_1_3_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.201800222"},{"key":"e_1_3_6_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2019.00206"},{"key":"e_1_3_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2015.07.012"},{"key":"e_1_3_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinre.2014.09.007"},{"key":"e_1_3_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2014.03.011"},{"key":"e_1_3_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2012.10.002"},{"key":"e_1_3_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2015.06.027"},{"key":"e_1_3_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2009.08.050"},{"key":"e_1_3_6_30_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-013-9991-8"},{"key":"e_1_3_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2019.112031"},{"key":"e_1_3_6_32_1","volume-title":"CompuSyn for drug combinations: PC software and user\u2019s guide: a computer program for quantification of synergism and antagonism in drug combinations and the determination of IC50 and ED50 and LD50 values","author":"Chou TC","year":"2005","unstructured":"Chou TC, Martin N. 2005. CompuSyn for drug combinations: PC software and user\u2019s guide: a computer program for quantification of synergism and antagonism in drug combinations and the determination of IC50 and ED50 and LD50 values. Paramus (NJ): ComboSyn, Inc."},{"key":"e_1_3_6_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.13281"},{"key":"e_1_3_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.synres.2015.04.001"},{"key":"e_1_3_6_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/03639045.2019.1583755"},{"key":"e_1_3_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2014.06.015"},{"key":"e_1_3_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2018.09.217"},{"key":"e_1_3_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1875-5364(18)30041-4"},{"key":"e_1_3_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2008.10.007"},{"key":"e_1_3_6_40_1","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-15-0098"},{"key":"e_1_3_6_41_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S77125"},{"key":"e_1_3_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2020.119330"},{"key":"e_1_3_6_43_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-017-0736-y"},{"key":"e_1_3_6_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcab.2019.101433"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2021.1995625","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T05:39:57Z","timestamp":1756964397000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2021.1995625"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1080\/07853890.2021.1995625"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2021.1995625","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-05-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-11","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}