{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:41:22Z","timestamp":1793814082841,"version":"4.6.1"},"reference-count":25,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T00:00:00Z","timestamp":1640131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Major Projects of Science and Technology Department in Anyang City","award":["ZDKJJS2020006"],"award-info":[{"award-number":["ZDKJJS2020006"]}]},{"DOI":"10.13039\/501100017700","name":"Henan Provincial Key Science and Technology Project","doi-asserted-by":"publisher","award":["212102310670"],"award-info":[{"award-number":["212102310670"]}],"id":[{"id":"10.13039\/501100017700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2022,12,31]]},"DOI":"10.1080\/07853890.2021.2016942","type":"journal-article","created":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T08:52:40Z","timestamp":1640163160000},"page":"51-62","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":19,"title":["Clinical impact of Fn-induced high expression of KIR2DL1 in CD8 T lymphocytes in oesophageal squamous cell carcinoma"],"prefix":"10.1080","volume":"54","author":[{"given":"Xiaopeng","family":"Wang","sequence":"first","affiliation":[{"name":"Anyang Tumor Hospital (The Fourth Affiliated Hospital of Henan University of Science and Technology)","place":["Anyang, China"]},{"name":"The Third Affiliated Hospital of Xinxiang Medical University","place":["Xinxiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwen","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Clinical Medicine, Laboratory of Molecular Biology of the First Affiliated Hospital, Cancer Institute of Henan University of Science and Technology, Henan Key Laboratory of Cancer Epigenetics","place":["Luoyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yannan","family":"Lu","sequence":"additional","affiliation":[{"name":"Graduate School of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simo","family":"Chen","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Xinxiang Medical University","place":["Xinxiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaoping","family":"Xing","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Xinxiang Medical University","place":["Xinxiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haijun","family":"Yang","sequence":"additional","affiliation":[{"name":"Anyang Tumor Hospital (The Fourth Affiliated Hospital of Henan University of Science and Technology)","place":["Anyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojun","family":"Wang","sequence":"additional","affiliation":[{"name":"Basic Medical School of Henan University of Science and Technology","place":["Luoyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaowen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Anyang Tumor Hospital (The Fourth Affiliated Hospital of Henan University of Science and Technology)","place":["Anyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Lymphoma & Hematology, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junkuo","family":"Li","sequence":"additional","affiliation":[{"name":"Anyang Tumor Hospital (The Fourth Affiliated Hospital of Henan University of Science and Technology)","place":["Anyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[{"name":"Anyang Tumor Hospital (The Fourth Affiliated Hospital of Henan University of Science and Technology)","place":["Anyang, China"]},{"name":"The Third Affiliated Hospital of Xinxiang Medical University","place":["Xinxiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Clinical Medicine, Laboratory of Molecular Biology of the First Affiliated Hospital, Cancer Institute of Henan University of Science and Technology, Henan Key Laboratory of Cancer Epigenetics","place":["Luoyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengxia","family":"Liang","sequence":"additional","affiliation":[{"name":"College of Clinical Medicine, Laboratory of Molecular Biology of the First Affiliated Hospital, Cancer Institute of Henan University of Science and Technology, Henan Key Laboratory of Cancer Epigenetics","place":["Luoyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuyou","family":"Zhou","sequence":"additional","affiliation":[{"name":"Anyang Tumor Hospital (The Fourth Affiliated Hospital of Henan University of Science and Technology)","place":["Anyang, China"]},{"name":"The Third Affiliated Hospital of Xinxiang Medical University","place":["Xinxiang, China"]},{"name":"College of Clinical Medicine, Laboratory of Molecular Biology of the First Affiliated Hospital, Cancer Institute of Henan University of Science and Technology, Henan Key Laboratory of Cancer Epigenetics","place":["Luoyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,12,22]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0000000000000249"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21176207"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/pore.2021.1609846"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ags3.12014"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina56010015"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-18-3962"},{"issue":"7","key":"e_1_3_4_8_1","first-page":"121","article-title":"The impact of KIR polymorphism on the risk of developing cancer: not as strong as imagined?","volume":"7","author":"Augusto DG.","year":"2016","unstructured":"Augusto DG. The impact of KIR polymorphism on the risk of developing cancer: not as strong as imagined? Front Genet. 2016;7(7):121.","journal-title":"Front Genet"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00251-014-0778-1"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-041015-055318"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature19330"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1718217115"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-18-0709"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmoldx.2011.08.002"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2001.19.23.4322"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2018.11.009"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10388-020-00782-1"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13402-019-00488-2"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/EDBK_236699"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2016.10.005"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2020.100972"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/pore.2021.628942"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32403"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2018.1553487"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-019-02426-5"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02048"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2021.2016942","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T09:50:52Z","timestamp":1757325052000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2021.2016942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,22]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12,31]]}},"alternative-id":["10.1080\/07853890.2021.2016942"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2021.2016942","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,22]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-09-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-23","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}