{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T05:07:04Z","timestamp":1787893624985,"version":"build-2784847793"},"reference-count":29,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:00:00Z","timestamp":1715817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2024,12,31]]},"DOI":"10.1080\/07853890.2024.2354683","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T14:47:42Z","timestamp":1715870862000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":4,"title":["Effect of on-demand vs continuous prescription of proton pump inhibitors on symptom burden and quality of life: results of a real-world randomized controlled trial in primary care patients with gastroesophageal reflux disease"],"prefix":"10.1080","volume":"56","author":[{"given":"Anna","family":"Andreasson","sequence":"first","affiliation":[{"name":"Division of Psychobiology and Epidemiology, Department of Psychology, Stockholm University","place":["Stockholm, Sweden"]},{"name":"Unit of Clinical Medicine, Department of Medicine Solna, Karolinska Institutet","place":["Stockholm, Sweden"]},{"name":"School of Psychological Sciences, Macquarie University","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Agr\u00e9us","sequence":"additional","affiliation":[{"name":"Division for Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet","place":["Huddinge, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Mastellos","sequence":"additional","affiliation":[{"name":"Department of Primary Care and Public Health, School of Public Health, Imperial College London","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Bli\u017aniuk","sequence":"additional","affiliation":[{"name":"Faculty of Cybernetics, Military University of Technology","place":["Warsaw, Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota","family":"Wa\u015bko-Czopnik","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Medical University Wroclaw ul. Borowska 213","place":["Wroclaw"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agapi","family":"Angelaki","sequence":"additional","affiliation":[{"name":"Clinic of Social and Family Medicine, School of Medicine, University of Crete","place":["Greece, Heraklion"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eirini","family":"Theodosaki","sequence":"additional","affiliation":[{"name":"Clinic of Social and Family Medicine, School of Medicine, University of Crete","place":["Greece, Heraklion"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Lionis","sequence":"additional","affiliation":[{"name":"Clinic of Social and Family Medicine, School of Medicine, University of Crete","place":["Greece, Heraklion"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Hek","sequence":"additional","affiliation":[{"name":"Nivel, Netherlands Institute for Health Services Research","place":["Utrecht, the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Verheij","sequence":"additional","affiliation":[{"name":"Nivel, Netherlands Institute for Health Services Research","place":["Utrecht, the Netherlands"]},{"name":"Tilburg School of Social and Behavioral Sciences, Tilburg University","place":["Tilburg, the Netherlands"]},{"name":"Health Care Institute Netherlands","place":["Diemen, the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Wright","sequence":"additional","affiliation":[{"name":"School of Life Course & Population Sciences, Faculty of Life Sciences and Medicine, King\u2019s College London","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stevo","family":"Durbaba","sequence":"additional","affiliation":[{"name":"School of Life Course & Population Sciences, Faculty of Life Sciences and Medicine, King\u2019s College London","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Muris","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Maastricht University, Care and Public Health Research Institute","place":["Maastricht, The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Br\u00f3dka","sequence":"additional","affiliation":[{"name":"Department of Artificial Intelligence, Wroclaw University of Science and Technology","place":["Wroclaw, Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislaw","family":"Saganowski","sequence":"additional","affiliation":[{"name":"Department of Artificial Intelligence, Wroclaw University of Science and Technology","place":["Wroclaw, Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Francois","family":"Ethi\u00e9r","sequence":"additional","affiliation":[{"name":"Groupe de recherche interdisciplinaire en informatique de la sant\u00e9 (GRIIS.ca), Universit\u00e9 de Sherbrooke","place":["Sherbrooke, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasa","family":"Curcin","sequence":"additional","affiliation":[{"name":"Department of Informatics, King\u2019s College London","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan","family":"Delaney","sequence":"additional","affiliation":[{"name":"Department of Department of Surgery and Cancer, Imperial College London","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,5,16]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)90287-f"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00630.x"},{"issue":"12","key":"e_1_3_4_4_1","first-page":"725","article-title":"Update on functional heartburn","volume":"13","author":"Yamasaki T","year":"2017","unstructured":"Yamasaki T, O\u2019Neil J, Fass R. Update on functional heartburn. Gastroenterol Hepatol (N Y). 2017;13(12):725\u2013734.","journal-title":"Gastroenterol Hepatol (N Y)"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520510011579"},{"issue":"3","key":"e_1_3_4_6_1","first-page":"23","article-title":"Barrett esophagus: history, definition and etiopathogeny","volume":"7","author":"Gindea C","year":"2014","unstructured":"Gindea C, Birla R, Hoara P, et\u00a0al. Barrett esophagus: history, definition and etiopathogeny. J Med Life. 2014;7(3):23\u201330.","journal-title":"J Med Life"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.706"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.041517"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.051821"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000972"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050640615623369"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/6417526"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-017-0532-9"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.5009\/gnl16615"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6773.2005.00404.x"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1497.2005.00291.x"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.2307\/2955359"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmv102"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmedinf.2017.06.006"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1109\/HICSS.2015.383"},{"key":"e_1_3_4_21_1","first-page":"231","article-title":"TRANSFoRm eHealth solution for quality of life monitoring","volume":"2016","author":"Saganowski S","year":"2016","unstructured":"Saganowski S, Misiaszek A, Brodka P, et\u00a0al. TRANSFoRm eHealth solution for quality of life monitoring. AMIA Jt Summits Transl Sci Proc. 2016;2016:231\u2013239.","journal-title":"AMIA Jt Summits Transl Sci Proc"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/1029368"},{"issue":"15","key":"e_1_3_4_23_1","article-title":"A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: the TRANSFoRm study protocol","volume":"10","author":"Mastellos N","year":"2015","unstructured":"Mastellos N, Andreasson A, Huckvale K, et\u00a0al. A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: the TRANSFoRm study protocol. Implement Sci. 2015;10(15).","journal-title":"Implement Sci"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.03451.x"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.305.6846.160"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60175-1"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2011.2"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-6-31"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.100263"},{"key":"e_1_3_4_30_1","first-page":"CD011969","article-title":"Deprescribing versus continuation of chronic proton pump inhibitor use in adults","volume":"3","author":"Boghossian TA","year":"2017","unstructured":"Boghossian TA, Rashid FJ, Thompson W, et\u00a0al. Deprescribing versus continuation of chronic proton pump inhibitor use in adults. Cochrane Database Syst Rev. 2017;3: CD011969.","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2024.2354683","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T15:52:06Z","timestamp":1756828326000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2024.2354683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,16]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,12,31]]}},"alternative-id":["10.1080\/07853890.2024.2354683"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2024.2354683","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,16]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2023-09-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-25","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2354683"}}