{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T18:57:48Z","timestamp":1780685868867,"version":"3.54.1"},"reference-count":38,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Rare Disease Drug Discovery Unit of Takeda Pharmaceuticals Company"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2024,12,31]]},"DOI":"10.1080\/07853890.2024.2402503","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T08:56:31Z","timestamp":1729760191000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":5,"title":["Combined miRNA transcriptome and proteome analysis of extracellular vesicles in urine and blood from the Pompe mouse model"],"prefix":"10.1080","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5153-2889","authenticated-orcid":false,"given":"David","family":"Merberg","sequence":"first","affiliation":[{"name":"Takeda Pharmaceutical Company Limited, Rare Disease Drug Discovery Unit, Cambridge, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0304-786X","authenticated-orcid":false,"given":"Rodney","family":"Moreland","sequence":"additional","affiliation":[{"name":"Takeda Pharmaceutical Company Limited, Rare Disease Drug Discovery Unit, Cambridge, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenqiang","family":"Su","sequence":"additional","affiliation":[{"name":"Takeda Pharmaceutical Company Limited, Preclinical and Translational Sciences, Cambridge, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Li","sequence":"additional","affiliation":[{"name":"Takeda Pharmaceutical Company Limited, Preclinical and Translational Sciences, Cambridge, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bob","family":"Crooker","sequence":"additional","affiliation":[{"name":"Takeda Pharmaceutical Company Limited, Rare Disease Drug Discovery Unit, Cambridge, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Palmieri","sequence":"additional","affiliation":[{"name":"Takeda Pharmaceutical Company Limited, Rare Disease Drug Discovery Unit, Cambridge, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1330-8381","authenticated-orcid":false,"given":"Simon W.","family":"Moore","sequence":"additional","affiliation":[{"name":"Takeda Pharmaceutical Company Limited, Rare Disease Drug Discovery Unit, Cambridge, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Melber","sequence":"additional","affiliation":[{"name":"Takeda Pharmaceutical Company Limited, Rare Disease Drug Discovery Unit, Cambridge, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruby","family":"Boyanapalli","sequence":"additional","affiliation":[{"name":"Takeda Pharmaceutical Company Limited, Rare Disease Drug Discovery Unit, Cambridge, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galen","family":"Carey","sequence":"additional","affiliation":[{"name":"Takeda Pharmaceutical Company Limited, Rare Disease Drug Discovery Unit, Cambridge, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahindra","family":"Makhija","sequence":"additional","affiliation":[{"name":"Takeda International \u2013 UK, London, England"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,10,24]]},"reference":[{"key":"e_1_3_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-022-00736-1"},{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056181"},{"key":"e_1_3_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgmr.2019.100475"},{"key":"e_1_3_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgmr.2023.100981"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2019.04.15"},{"key":"e_1_3_6_7_1","doi-asserted-by":"publisher","DOI":"10.1006\/abio.2000.483811078593"},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.1974.tb02358.x"},{"key":"e_1_3_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/tra.12803"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21061908"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.121.318897"},{"key":"e_1_3_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv007"},{"key":"e_1_3_6_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-13-S16-S13"},{"key":"e_1_3_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw313"},{"key":"e_1_3_6_15_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.15931.2"},{"key":"e_1_3_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr026"},{"key":"e_1_3_6_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2009-10-3-r25"},{"key":"e_1_3_6_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/gigascience\/giab008"},{"key":"e_1_3_6_19_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.8987.2"},{"key":"e_1_3_6_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/6981"},{"key":"e_1_3_6_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mt.6300355"},{"key":"e_1_3_6_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-6606-7-17"},{"key":"e_1_3_6_23_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.3.7.1019"},{"key":"e_1_3_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.02.016"},{"key":"e_1_3_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2015.12.013"},{"key":"e_1_3_6_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080263"},{"key":"e_1_3_6_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41436-018-0103-8"},{"key":"e_1_3_6_28_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.13966"},{"key":"e_1_3_6_29_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.05005"},{"key":"e_1_3_6_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12227"},{"key":"e_1_3_6_31_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00090.2014"},{"key":"e_1_3_6_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2843"},{"key":"e_1_3_6_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/emmm.201100133"},{"key":"e_1_3_6_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12199-014-0405-7"},{"key":"e_1_3_6_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.50800"},{"key":"e_1_3_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2018.01.059"},{"key":"e_1_3_6_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/proteomes7020018"},{"key":"e_1_3_6_38_1","doi-asserted-by":"publisher","DOI":"10.3724\/SP.J.1123.2021.04009"},{"key":"e_1_3_6_39_1","doi-asserted-by":"publisher","DOI":"10.26508\/lsa.202101215"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2024.2402503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T10:38:58Z","timestamp":1733222338000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2024.2402503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,24]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,12,31]]}},"alternative-id":["10.1080\/07853890.2024.2402503"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2024.2402503","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,24]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-01-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-26","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2402503"}}