{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:20:57Z","timestamp":1790659257450,"version":"4.1.0"},"reference-count":39,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T00:00:00Z","timestamp":1747008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007156","name":"Hong Kong Innovation and Technology Fund","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007156","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Guangdong-Hong Kong Technology Cooperation Funding Scheme (TCFS) from Hong Kong Innovation and Technology Commission","award":["GHP\/138\/18SZ"],"award-info":[{"award-number":["GHP\/138\/18SZ"]}]},{"name":"Grant of Shenzhen-Hong Kong Innovation Circle from Shenzhen Science and Technology Innovation Committee","award":["SGLH20180629094602262"],"award-info":[{"award-number":["SGLH20180629094602262"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2025,12,31]]},"DOI":"10.1080\/07853890.2025.2500689","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T06:39:05Z","timestamp":1747118345000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":5,"title":["Circulating fibroblast growth factor 21 is associated with blood pressure in the Chinese population: a community-based study"],"prefix":"10.1080","volume":"57","author":[{"given":"Juanying","family":"Zhen","sequence":"first","affiliation":[{"name":"Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital","place":["Pokfulam, Hong Kong SAR, China"]},{"name":"Department of Neurology, Peking University Shenzhen Hospital","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Shenzhen Longhua District Central Hospital","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital","place":["Pokfulam, Hong Kong SAR, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodan","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Neurology, Peking University Shenzhen Hospital","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoru","family":"Zhao","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems, Research Center for Neural Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianguo","family":"Liang","sequence":"additional","affiliation":[{"name":"\u2019Precision Health Research Center Company Limited","place":["Hong Kong SAR, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimin","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital","place":["Pokfulam, Hong Kong SAR, China"]},{"name":"State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong","place":["Pokfulam, Hong Kong SAR, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7543-3973","authenticated-orcid":false,"given":"Chao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital","place":["Pokfulam, Hong Kong SAR, China"]},{"name":"Department of Neurology, Peking University Shenzhen Hospital","place":["Shenzhen, China"]},{"name":"State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong","place":["Pokfulam, Hong Kong SAR, China"]},{"name":"Department of Neurology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People\u2019s Hospital","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijie","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People\u2019s Hospital","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Peking University Shenzhen Hospital","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9106-7363","authenticated-orcid":false,"given":"Bernard Man Yung","family":"Cheung","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital","place":["Pokfulam, Hong Kong SAR, China"]},{"name":"State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong","place":["Pokfulam, Hong Kong SAR, China"]},{"name":"Department of Neurology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People\u2019s Hospital","place":["Shenzhen, China"]},{"name":"Institute of Cardiovascular Science and Medicine, The University of Hong Kong","place":["Pokfulam, Hong Kong SAR, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,5,12]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-021115-105339"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2022.155166"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2008-0816"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0065763"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/db08-0392"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/db07-1476"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-0684"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-014-3458-7"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2022.155329"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.120.314356"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-3308"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n365"},{"issue":"10304","key":"e_1_3_4_14_1","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/S0140-6736(21)01330-1","article-title":"Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants","volume":"398","author":"NCD Risk Factor Collaboration","year":"2021","unstructured":"NCD Risk Factor Collaboration. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 2021;398(10304):957\u2013980.","journal-title":"Lancet"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-0294"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.113.301599"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.015308"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-2267"},{"key":"e_1_3_4_19_1","unstructured":"ImmunoDiagnostics Limited; 2023 [accessed 2023 Aug 17]. Available from: https:\/\/www.immunodiagnostics.com.hk\/"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1114248"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780080504"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2012.52"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2023.01.033"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.113.02989"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.07.023"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000228"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/1687-9856-2014-7"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgac729"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2018.10.011"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2018.01.017"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2019.06.898"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2018.04.002"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2021.174470"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-018-0894-7"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2018.06.013"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.2337\/db14-0541"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.2337\/db15-1029"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2013.08.005"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2017.75"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-012-0227-2"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2025.2500689","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T06:39:08Z","timestamp":1747118348000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2025.2500689"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,12]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12,31]]}},"alternative-id":["10.1080\/07853890.2025.2500689"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2025.2500689","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,12]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2023-09-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-19","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2500689"}}