{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T04:45:51Z","timestamp":1793853951158,"version":"4.6.1"},"reference-count":81,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Research and Innovation Team Project for Scientific Breakthroughs at Shanxi Bethune Hospital","award":["2024OAXIANG01"],"award-info":[{"award-number":["2024OAXIANG01"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2025,12,31]]},"DOI":"10.1080\/07853890.2025.2584413","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T09:30:29Z","timestamp":1762421429000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":5,"title":["The role of neutrophils in bronchiectasis"],"prefix":"10.1080","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5689-3990","authenticated-orcid":false,"given":"Jifang","family":"Liang","sequence":"first","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital","place":["Taiyuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueli","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital","place":["Taiyuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiansheng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital","place":["Taiyuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,11,6]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1385\/CRIAI:25:3:233"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0000000000000858"},{"issue":"6","key":"e_1_3_4_4_1","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1056\/NEJMra2202819","article-title":"Bronchiectasis - a clinical review","volume":"387","author":"O\u2019Donnell AE.","year":"2022","unstructured":"O\u2019Donnell AE. Bronchiectasis - a clinical review. N Engl J Med. 2022;387(6):533\u2013545.","journal-title":"N Engl J Med"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2023.104174"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccm.2021.11.003"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.13163"},{"issue":"6","key":"e_1_3_4_8_1","first-page":"437","article-title":"The influence of IL-3, IL-5, and GM-CSF on normal human eosinophil and neutrophil C3b-induced degranulation","volume":"48","author":"Carlson M","year":"1993","unstructured":"Carlson M, Peterson C, Venge P. The influence of IL-3, IL-5, and GM-CSF on normal human eosinophil and neutrophil C3b-induced degranulation. Allergy. 1993;48(6):437\u2013442.","journal-title":"Allergy"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1359-6101(97)00022-1"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/v13112318"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0810457"},{"issue":"41","key":"e_1_3_4_12_1","first-page":"1403","article-title":"Phagocytes and phagocytosis 100 years after Metchnikoff. A current picture of the neutrophil leukocyte","volume":"112","author":"Baggiolini M.","year":"1982","unstructured":"Baggiolini M. Phagocytes and phagocytosis 100 years after Metchnikoff. A current picture of the neutrophil leukocyte. Schweiz Med Wochenschr. 1982;112(41):1403\u20131411.","journal-title":"Schweiz Med Wochenschr"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0712349"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232112855"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3399"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0891-5849(02)00823-7"},{"issue":"2","key":"e_1_3_4_17_1","article-title":"Potent and broad but not unselective cleavage of cytokines and chemokines by human neutrophil elastase and proteinase 3","volume":"21","author":"Fu Z","year":"2020","unstructured":"Fu Z, Akula S, Thorpe M, et al. Potent and broad but not unselective cleavage of cytokines and chemokines by human neutrophil elastase and proteinase 3. Int J Mol Sci. 2020;21(2):651.","journal-title":"Int J Mol Sci"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.3724\/zdxbyxb-2021-0030"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201612-2476ED"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1730891"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.98.12051200"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3547"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2016.04.003"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2020.8203"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.16819"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.01011"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.3.9908016"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.301.1.258"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1385\/CRIAI:27:1:035"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/17476348.2018.1526677"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/omi.12252"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.03.049"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6639199"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2008.07.001"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2020.107272"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.12.046"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3024"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1159\/000284367"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/01902140701756620"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.2000.00092.x"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.1069929"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1301725"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2018.01.004"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30504-X"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)31554-X"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2021.109568"},{"issue":"24","key":"e_1_3_4_47_1","first-page":"67","article-title":"Effectiveness evaluation on Xuanfei Jiangzhuo Qingchang Decoction in treatment of stable bronchiectasis","author":"Zhu HP","year":"2022","unstructured":"Zhu HP, Zhang ZM, Xie XS, et al. Effectiveness evaluation on Xuanfei Jiangzhuo Qingchang Decoction in treatment of stable bronchiectasis. J Hubei Univ Chin Med. 2022;24(01):67\u201369.","journal-title":"J Hubei Univ Chin Med"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1080\/10715760310001623331"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-23-780"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.02.016"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.180132"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0000000000002466"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-40021-6"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/jleuko\/qiae243"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-024-02931-x"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/3291957"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15597"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2023.04.029"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13505"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2020.114147"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0055-2019"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2022.07.007"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S368645"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12091713"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.12932\/AP-100620-0878"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41374-021-00652-z"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2023.102283"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2024.156563"},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.211242"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina59111960"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2019.1628536"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2021.105934"},{"key":"e_1_3_4_73_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00151-2024"},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021713"},{"key":"e_1_3_4_75_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2411664"},{"key":"e_1_3_4_76_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-023-02444-z"},{"key":"e_1_3_4_77_1","unstructured":"Haisco Pharmaceutical Group. Safety tolerability PK\/PD food effect of single and multiple ascending doses of HSK31858 in healthy volunteers. 2022. https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT05663593 Date last"},{"key":"e_1_3_4_78_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00725-2023"},{"key":"e_1_3_4_79_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01551-2024"},{"key":"e_1_3_4_80_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S408325"},{"key":"e_1_3_4_81_1","doi-asserted-by":"publisher","DOI":"10.17116\/kurort20219802170"},{"key":"e_1_3_4_82_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00629-2017"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2025.2584413","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T09:30:34Z","timestamp":1762421434000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2025.2584413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,6]]},"references-count":81,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12,31]]}},"alternative-id":["10.1080\/07853890.2025.2584413"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2025.2584413","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,6]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-04-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2584413"}}