{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T08:07:33Z","timestamp":1781770053782,"version":"3.54.5"},"reference-count":90,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"the National Clinical Research center for Otolaryngologic Diseases and National Key Research and Development Program","award":["2022YFC2402705"],"award-info":[{"award-number":["2022YFC2402705"]}]},{"name":"the National Clinical Research center for Otolaryngologic Diseases and National Key Research and Development Program","award":["2022YFC2402701"],"award-info":[{"award-number":["2022YFC2402701"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2025,12,31]]},"DOI":"10.1080\/07853890.2025.2584694","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T08:00:41Z","timestamp":1762761641000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["Mid-infrared photons relieve tinnitus-like behavior of mice by regulating HCN2 ion channels in the medial geniculate body"],"prefix":"10.1080","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0005-4207","authenticated-orcid":false,"given":"Xinmiao","family":"Xue","sequence":"first","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Bethune International Peace Hospital","place":["Shijiazhuang, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixin","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanwen","family":"Zhou","sequence":"additional","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Ding","sequence":"additional","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuke","family":"Jiang","sequence":"additional","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhan","family":"Lu","sequence":"additional","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weidong","family":"Shen","sequence":"additional","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Bethune International Peace Hospital","place":["Shijiazhuang, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Sun","sequence":"additional","affiliation":[{"name":"Beijing Institute of Pharmacology and Toxicity","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxia","family":"Jiang","sequence":"additional","affiliation":[{"name":"Beijing Institute of Basic Medical Sciences","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiming","family":"Yang","sequence":"additional","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyuan","family":"Wang","sequence":"additional","affiliation":[{"name":"The Six Medical Center, PLA General Hospital","place":["Beijing, PR China"]},{"name":"Medical School of Chinese PLA","place":["Beijing, PR China"]},{"name":"Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital","place":["Beijing, PR China"]},{"name":"State Key Laboratory of Hearing and Balance Science","place":["Beijing, PR China"]},{"name":"National Clinical Research Center for Otolaryngologic Diseases","place":["Beijing, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,11,10]]},"reference":[{"key":"e_1_3_6_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0261257"},{"issue":"9","key":"e_1_3_6_3_1","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1001\/jamaneurol.2022.2189","article-title":"Global prevalence and incidence of tinnitus: a systematic review and meta-analysis","volume":"79","author":"Jarach CM","year":"2022","unstructured":"Jarach CM, Lugo A, Scala M, et al. Global prevalence and incidence of tinnitus: a systematic review and meta-analysis. JAMA Neurol. 2022;79(9):888\u2013900.","journal-title":"JAMA Neurol"},{"issue":"11","key":"e_1_3_6_4_1","first-page":"663","article-title":"Tinnitus: diagnosis and management","volume":"103","author":"Dalrymple SN","year":"2021","unstructured":"Dalrymple SN, Lewis SH, Philman S. Tinnitus: diagnosis and management. Am Fam Physician. 2021;103(11):663\u2013671.","journal-title":"Am Fam Physician"},{"issue":"1","key":"e_1_3_6_5_1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s10162-022-00874-y","article-title":"Low evidence for tinnitus risk factors: a systematic review and meta-analysis","volume":"24","author":"Biswas R","year":"2023","unstructured":"Biswas R, Genitsaridi E, Trpchevska N, et al. Low evidence for tinnitus risk factors: a systematic review and meta-analysis. J Assoc Res Otolaryngol. 2023;24(1):81\u201394.","journal-title":"J Assoc Res Otolaryngol"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2020.101893"},{"key":"e_1_3_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2019.01.027"},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2019.05.008"},{"issue":"9","key":"e_1_3_6_9_1","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1038\/nn.2373","article-title":"Change detection by thalamic reticular neurons","volume":"12","author":"Yu XJ","year":"2009","unstructured":"Yu XJ, Xu XX, He S, et al. Change detection by thalamic reticular neurons. Nat Neurosci. 2009;12(9):1165\u20131170.","journal-title":"Nat Neurosci"},{"issue":"2","key":"e_1_3_6_10_1","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1152\/jn.91130.2008","article-title":"Slow recovery from excitation of thalamic reticular nucleus neurons","volume":"101","author":"Yu XJ","year":"2009","unstructured":"Yu XJ, Xu XX, Chen X, et al. Slow recovery from excitation of thalamic reticular nucleus neurons. J Neurophysiol. 2009;101(2):980\u2013987.","journal-title":"J Neurophysiol"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.04.032"},{"issue":"38","key":"e_1_3_6_12_1","doi-asserted-by":"crossref","first-page":"7190","DOI":"10.1523\/JNEUROSCI.1314-19.2020","article-title":"The neural bases of tinnitus: lessons from deafness and cochlear implants","volume":"40","author":"Knipper M","year":"2020","unstructured":"Knipper M, VAN Dijk P, Schulze H, et al. The neural bases of tinnitus: lessons from deafness and cochlear implants. J Neurosci. 2020;40(38):7190\u20137202.","journal-title":"J Neurosci"},{"issue":"5","key":"e_1_3_6_13_1","doi-asserted-by":"crossref","first-page":"e378","DOI":"10.1002\/ctm2.378","article-title":"Functional biomarkers that distinguish between tinnitus with and without hyperacusis","volume":"11","author":"Hofmeier B","year":"2021","unstructured":"Hofmeier B, Wertz J, Refat F, et al. Functional biomarkers that distinguish between tinnitus with and without hyperacusis. Clin Transl Med. 2021;11(5):e378.","journal-title":"Clin Transl Med"},{"key":"e_1_3_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-021-02284-x"},{"key":"e_1_3_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2005.04.006"},{"issue":"2","key":"e_1_3_6_16_1","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1002\/cne.902570212","article-title":"Patterns of reciprocity in auditory thalamocortical and corticothalamic connections: study with horseradish peroxidase and autoradiographic methods in the rat medial geniculate body","volume":"257","author":"Winer JA","year":"1987","unstructured":"Winer JA, Larue DT. Patterns of reciprocity in auditory thalamocortical and corticothalamic connections: study with horseradish peroxidase and autoradiographic methods in the rat medial geniculate body. J Comp Neurol. 1987;257(2):282\u2013315.","journal-title":"J Comp Neurol"},{"issue":"1","key":"e_1_3_6_17_1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0304-3940(91)90526-Y","article-title":"Overlapping projections to the amygdala and striatum from auditory processing areas of the thalamus and cortex","volume":"134","author":"Ledoux JE","year":"1991","unstructured":"Ledoux JE, Farb CR, Romanski LM. Overlapping projections to the amygdala and striatum from auditory processing areas of the thalamus and cortex. Neurosci Lett. 1991;134(1):139\u2013144.","journal-title":"Neurosci Lett"},{"issue":"1","key":"e_1_3_6_18_1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0378-5955(94)00199-Z","article-title":"Morphology and spatial distribution of corticothalamic terminals originating from the cat auditory cortex","volume":"83","author":"Bajo VM","year":"1995","unstructured":"Bajo VM, Rouiller EM, Welker E, et al. Morphology and spatial distribution of corticothalamic terminals originating from the cat auditory cortex. Hear Res. 1995;83(1\u20132):161\u2013174.","journal-title":"Hear Res"},{"issue":"1","key":"e_1_3_6_19_1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0378-5955(98)00216-0","article-title":"Neural architecture of the rat medial geniculate body","volume":"130","author":"Winer JA","year":"1999","unstructured":"Winer JA, Kelly JB, Larue DT. Neural architecture of the rat medial geniculate body. Hear Res. 1999;130(1\u20132):19\u201341.","journal-title":"Hear Res"},{"issue":"6","key":"e_1_3_6_20_1","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1002\/cne.21611","article-title":"Connections of cat auditory cortex: I. Thalamocortical system","volume":"507","author":"Lee CC","year":"2008","unstructured":"Lee CC, Winer JA. Connections of cat auditory cortex: I. Thalamocortical system. J Comp Neurol. 2008;507(6):1879\u20131900.","journal-title":"J Comp Neurol"},{"key":"e_1_3_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.12.002"},{"key":"e_1_3_6_22_1","doi-asserted-by":"crossref","first-page":"108190","DOI":"10.1016\/j.heares.2021.108190","article-title":"Spontaneous firing patterns in the medial geniculate nucleus in a guinea pig model of tinnitus","volume":"403","author":"Cook JA","year":"2021","unstructured":"Cook JA, Barry KM, Zimdahl JW, et al. Spontaneous firing patterns in the medial geniculate nucleus in a guinea pig model of tinnitus. Hear Res. 2021;403:108190.","journal-title":"Hear Res"},{"key":"e_1_3_6_23_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2014.278572"},{"key":"e_1_3_6_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhj070"},{"key":"e_1_3_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.01.069"},{"key":"e_1_3_6_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-018-0162-z"},{"key":"e_1_3_6_27_1","first-page":"4:e07242","article-title":"Noise-induced plasticity of KCNQ2\/3 and HCN channels underlies vulnerability and resilience to tinnitus","author":"Li S","year":"2015","unstructured":"Li S, Kalappa BI, Tzounopoulos T. Noise-induced plasticity of KCNQ2\/3 and HCN channels underlies vulnerability and resilience to tinnitus. Elife. 2015:4:e07242.","journal-title":"Elife"},{"key":"e_1_3_6_28_1","doi-asserted-by":"crossref","first-page":"698516","DOI":"10.3389\/fnbeh.2021.698516","article-title":"Salicylate-induced changes in hearing thresholds in mongolian gerbils are correlated with tinnitus frequency but not with tinnitus strength","volume":"15","author":"Lanaia V","year":"2021","unstructured":"Lanaia V, Tziridis K, Schulze H. Salicylate-induced changes in hearing thresholds in mongolian gerbils are correlated with tinnitus frequency but not with tinnitus strength. Front Behav Neurosci. 2021;15:698516.","journal-title":"Front Behav Neurosci"},{"key":"e_1_3_6_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2169"},{"key":"e_1_3_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/ner.12795"},{"issue":"5","key":"e_1_3_6_31_1","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1016\/j.brs.2023.08.016","article-title":"Effective treatment of refractory tinnitus by bilateral deep brain stimulation of the medial geniculate body of the thalamus: a case report","volume":"16","author":"Devos JVP","year":"2023","unstructured":"Devos JVP, Smit JV, George ELJ, et al. Effective treatment of refractory tinnitus by bilateral deep brain stimulation of the medial geniculate body of the thalamus: a case report. Brain Stimul. 2023;16(5):1322\u20131324.","journal-title":"Brain Stimul"},{"key":"e_1_3_6_32_1","first-page":"0010","article-title":"Neuromodulation of chemical synaptic transmission driven by THz photons","volume":"2022","author":"Tan X","year":"2022","unstructured":"Tan X, Zhong Y, Li R, et al. Neuromodulation of chemical synaptic transmission driven by THz photons. Research (Wash D C). 2022;2022:0010.","journal-title":"Research (Wash D C)"},{"key":"e_1_3_6_33_1","article-title":"Progress on cutting-edge infrared-terahertz biophysics","author":"Wang P","year":"2022","unstructured":"Wang P, Lou J, Fang G, et al. Progress on cutting-edge infrared-terahertz biophysics. IEEE Trans Microw Theory Techn. 2022.","journal-title":"IEEE Trans Microw Theory Techn"},{"key":"e_1_3_6_34_1","first-page":"0479","article-title":"Mid-infrared photons alleviate tinnitus by activating the KCNQ2 channel in the auditory cortex","volume":"7","author":"Liu P","year":"2024","unstructured":"Liu P, Xue X, Zhang C, et al. Mid-infrared photons alleviate tinnitus by activating the KCNQ2 channel in the auditory cortex. Research (Wash DC). 2024;7:0479.","journal-title":"Research (Wash DC)"},{"key":"e_1_3_6_35_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1100223108"},{"key":"e_1_3_6_36_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1302770110"},{"issue":"11","key":"e_1_3_6_37_1","doi-asserted-by":"crossref","first-page":"e0294236","DOI":"10.1371\/journal.pone.0294236","article-title":"SRplot: a free online platform for data visualization and graphing","volume":"18","author":"Tang D","year":"2023","unstructured":"Tang D, Chen M, Huang X, et al. SRplot: a free online platform for data visualization and graphing. PLoS One. 2023;18(11):e0294236.","journal-title":"PLoS One"},{"key":"e_1_3_6_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky1131"},{"key":"e_1_3_6_39_1","first-page":"102","article-title":"A systems biology approach to reveal putative host-derived biomarkers of periodontitis by network topology characterization of MMP-REDOX\/NO and apoptosis integrated pathways","volume":"5","author":"ZEID\u00e1N-CHULI\u00e1 F","year":"2015","unstructured":"ZEID\u00e1N-CHULI\u00e1 F, G\u00fcRSOY M, Neves DE Oliveira BH, et al. A systems biology approach to reveal putative host-derived biomarkers of periodontitis by network topology characterization of MMP-REDOX\/NO and apoptosis integrated pathways. Front Cell Infect Microbiol. 2015;5:102.","journal-title":"Front Cell Infect Microbiol"},{"key":"e_1_3_6_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biosystems.2014.11.005"},{"issue":"4","key":"e_1_3_6_41_1","first-page":"387","article-title":"Dendritic organization in the neurons of the visual and motor cortices of the cat","volume":"87","author":"Sholl DA.","year":"1953","unstructured":"Sholl DA. Dendritic organization in the neurons of the visual and motor cortices of the cat. J Anat. 1953;87(4):387\u2013406.","journal-title":"J Anat"},{"key":"e_1_3_6_42_1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.neuroscience.2016.03.011","article-title":"Hippocampal neuronal subtypes develop abnormal dendritic arbors in the presence of Fragile X astrocytes","volume":"324","author":"Jacobs S","year":"2016","unstructured":"Jacobs S, Cheng C, Doering LC. Hippocampal neuronal subtypes develop abnormal dendritic arbors in the presence of Fragile X astrocytes. Neuroscience. 2016;324:202\u2013217.","journal-title":"Neuroscience"},{"key":"e_1_3_6_43_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2018.6260"},{"issue":"12","key":"e_1_3_6_44_1","doi-asserted-by":"crossref","first-page":"e115556","DOI":"10.1371\/journal.pone.0115556","article-title":"Role of synaptic structural plasticity in impairments of spatial learning and memory induced by developmental lead exposure in Wistar rats","volume":"9","author":"Xiao Y","year":"2014","unstructured":"Xiao Y, Fu H, Han X, et al. Role of synaptic structural plasticity in impairments of spatial learning and memory induced by developmental lead exposure in Wistar rats. PLoS One. 2014;9(12):e115556.","journal-title":"PLoS One"},{"key":"e_1_3_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2013.03.004"},{"issue":"1","key":"e_1_3_6_46_1","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1038\/s41467-019-08350-7","article-title":"Medial geniculate body and primary auditory cortex differentially contribute to striatal sound representations","volume":"10","author":"Chen L","year":"2019","unstructured":"Chen L, Wang X, Ge S, et al. Medial geniculate body and primary auditory cortex differentially contribute to striatal sound representations. Nat Commun. 2019;10(1):418.","journal-title":"Nat Commun"},{"key":"e_1_3_6_47_1","article-title":"The Allen Atlas: a digital brain atlas of C57BL\/6J male mouse, (with CD-ROM)","author":"Dong HW.","year":"2007","unstructured":"Dong HW. The Allen Atlas: a digital brain atlas of C57BL\/6J male mouse, (with CD-ROM). Wiley. 2007.","journal-title":"Wiley"},{"issue":"2","key":"e_1_3_6_48_1","first-page":"267","article-title":"Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy","volume":"15","author":"Li KX","year":"2011","unstructured":"Li KX, Lu YM, Xu ZH, et al. Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy. Nat Neurosci. 2011;15(2):267\u2013273.","journal-title":"Nat Neurosci"},{"issue":"7","key":"e_1_3_6_49_1","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1113\/JP275147","article-title":"Shank3-deficient thalamocortical neurons show HCN channelopathy and alterations in intrinsic electrical properties","volume":"596","author":"Zhu M","year":"2018","unstructured":"Zhu M, Idikuda VK, Wang J, et al. Shank3-deficient thalamocortical neurons show HCN channelopathy and alterations in intrinsic electrical properties. J Physiol. 2018;596(7):1259\u20131276.","journal-title":"J Physiol"},{"issue":"5","key":"e_1_3_6_50_1","doi-asserted-by":"crossref","first-page":"3160","DOI":"10.1152\/jn.2000.83.5.3160","article-title":"Time-dependent changes in input resistance of rat hypoglossal motoneurons associated with whole-cell recording","volume":"83","author":"Robinson DW","year":"2000","unstructured":"Robinson DW, Cameron WE. Time-dependent changes in input resistance of rat hypoglossal motoneurons associated with whole-cell recording. J Neurophysiol. 2000;83(5):3160\u20133164.","journal-title":"J Neurophysiol"},{"key":"e_1_3_6_51_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S163951"},{"key":"e_1_3_6_52_1","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_3_6_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.softx.2015.06.001"},{"key":"e_1_3_6_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20945"},{"key":"e_1_3_6_55_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevA.31.1695"},{"key":"e_1_3_6_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/0263-7855(96)00018-5"},{"key":"e_1_3_6_57_1","doi-asserted-by":"crossref","first-page":"929461","DOI":"10.3389\/fnins.2023.929461","article-title":"cFOS as a biomarker of activity maturation in the hippocampal formation","volume":"17","author":"Pompeiano M","year":"2023","unstructured":"Pompeiano M, Colonnese MT. cFOS as a biomarker of activity maturation in the hippocampal formation. Front Neurosci. 2023;17:929461.","journal-title":"Front Neurosci"},{"issue":"5","key":"e_1_3_6_58_1","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.immuni.2021.04.007","article-title":"Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation","volume":"54","author":"Schiller M","year":"2021","unstructured":"Schiller M, Azulay-Debby H, Boshnak N, et al. Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation. Immunity. 2021;54(5):1022\u20131036.","journal-title":"Immunity"},{"key":"e_1_3_6_59_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4825-14.2015"},{"key":"e_1_3_6_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2021.06.002"},{"issue":"10","key":"e_1_3_6_61_1","article-title":"Nonthermal and reversible control of neuronal signaling and behavior by midinfrared stimulation","volume":"118","author":"Liu X","year":"2021","unstructured":"Liu X, Qiao Z, Chai Y, et al. Nonthermal and reversible control of neuronal signaling and behavior by midinfrared stimulation. Proc Natl Acad Sci USA. 2021;118(10):e2015685118.","journal-title":"Proc Natl Acad Sci USA"},{"key":"e_1_3_6_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2022.147797"},{"key":"e_1_3_6_63_1","doi-asserted-by":"crossref","first-page":"106619","DOI":"10.1016\/j.nbd.2024.106619","article-title":"Neurophysiological, structural, and molecular alterations in the prefrontal and auditory cortices following noise-induced hearing loss","volume":"200","author":"Hayes SH","year":"2024","unstructured":"Hayes SH, Patel SV, Arora P, et al. Neurophysiological, structural, and molecular alterations in the prefrontal and auditory cortices following noise-induced hearing loss. Neurobiol Dis. 2024;200:106619.","journal-title":"Neurobiol Dis"},{"issue":"3","key":"e_1_3_6_64_1","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/nrn2286","article-title":"Pyramidal neurons: dendritic structure and synaptic integration","volume":"9","author":"Spruston N.","year":"2008","unstructured":"Spruston N. Pyramidal neurons: dendritic structure and synaptic integration. Nat Rev Neurosci. 2008;9(3):206\u2013221.","journal-title":"Nat Rev Neurosci"},{"key":"e_1_3_6_65_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00053.2018"},{"key":"e_1_3_6_66_1","doi-asserted-by":"publisher","DOI":"10.1109\/TNSRE.2018.2863740"},{"key":"e_1_3_6_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0361-9230(96)00107-4"},{"key":"e_1_3_6_68_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1840-19.2019"},{"key":"e_1_3_6_69_1","doi-asserted-by":"crossref","first-page":"598406","DOI":"10.3389\/fnins.2020.598406","article-title":"Acute and long-term circuit-level effects in the auditory cortex after sound trauma","volume":"14","author":"Jeschke M","year":"2020","unstructured":"Jeschke M, Happel MFK, Tziridis K, et al. Acute and long-term circuit-level effects in the auditory cortex after sound trauma. Front Neurosci. 2020;14:598406.","journal-title":"Front Neurosci"},{"key":"e_1_3_6_70_1","first-page":"0535","article-title":"Terahertz wave alleviates comorbidity anxiety in pain by reducing the binding capacity of nanostructured glutamate molecules to GluA2","volume":"7","author":"Song Z","year":"2024","unstructured":"Song Z, Sun Y, Liu P, et al. Terahertz wave alleviates comorbidity anxiety in pain by reducing the binding capacity of nanostructured glutamate molecules to GluA2. Research (Wash D C). 2024;7:0535.","journal-title":"Research (Wash D C)"},{"issue":"1","key":"e_1_3_6_71_1","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1038\/s41467-021-23025-y","article-title":"Non-invasive, opsin-free mid-infrared modulation activates cortical neurons and accelerates associative learning","volume":"12","author":"Zhang J","year":"2021","unstructured":"Zhang J, He Y, Liang S, et al. Non-invasive, opsin-free mid-infrared modulation activates cortical neurons and accelerates associative learning. Nat Commun. 2021;12(1):2730.","journal-title":"Nat Commun"},{"key":"e_1_3_6_72_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awad255"},{"key":"e_1_3_6_73_1","doi-asserted-by":"publisher","DOI":"10.1162\/neco.1997.9.5.1001"},{"issue":"2","key":"e_1_3_6_74_1","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1152\/jn.00752.2019","article-title":"Noise-induced neurophysiological alterations in the rat medial geniculate body and thalamocortical desynchronization by deep brain stimulation","volume":"125","author":"VAN Zwieten G","year":"2021","unstructured":"VAN Zwieten G, Roberts MJ, Schaper F, et al. Noise-induced neurophysiological alterations in the rat medial geniculate body and thalamocortical desynchronization by deep brain stimulation. J Neurophysiol. 2021;125(2):661\u2013671.","journal-title":"J Neurophysiol"},{"key":"e_1_3_6_75_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-199101000-00005"},{"key":"e_1_3_6_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41386-022-01453-8"},{"key":"e_1_3_6_77_1","first-page":"12:e78729","article-title":"Sensory input-dependent gain modulation of the optokinetic nystagmus by mid-infrared stimulation in pigeons","author":"Xiao T","year":"2023","unstructured":"Xiao T, Wu K, Wang P, et al. Sensory input-dependent gain modulation of the optokinetic nystagmus by mid-infrared stimulation in pigeons. Elife. 2023:12:e78729.","journal-title":"Elife"},{"issue":"5","key":"e_1_3_6_78_1","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/nn.2307","article-title":"HCN hyperpolarization-activated cation channels inhibit EPSPs by interactions with M-type K(+) channels","volume":"12","author":"George MS","year":"2009","unstructured":"George MS, Abbott LF, Siegelbaum SA. HCN hyperpolarization-activated cation channels inhibit EPSPs by interactions with M-type K(+) channels. Nat Neurosci. 2009;12(5):577\u2013584.","journal-title":"Nat Neurosci"},{"key":"e_1_3_6_79_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0036867"},{"issue":"2","key":"e_1_3_6_80_1","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1152\/jn.00647.2013","article-title":"The interplay of seven subthreshold conductances controls the resting membrane potential and the oscillatory behavior of thalamocortical neurons","volume":"112","author":"Amarillo Y","year":"2014","unstructured":"Amarillo Y, Zagha E, Mato G, et al. The interplay of seven subthreshold conductances controls the resting membrane potential and the oscillatory behavior of thalamocortical neurons. J Neurophysiol. 2014;112(2):393\u2013410.","journal-title":"J Neurophysiol"},{"key":"e_1_3_6_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2018.08.042"},{"key":"e_1_3_6_82_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.11039"},{"issue":"5","key":"e_1_3_6_83_1","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1364\/OL.30.000504","article-title":"Optical stimulation of neural tissue in vivo","volume":"30","author":"Wells J","year":"2005","unstructured":"Wells J, Kao C, Mariappan K, et al. Optical stimulation of neural tissue in vivo. Opt Lett. 2005;30(5):504\u2013506.","journal-title":"Opt Lett"},{"key":"e_1_3_6_84_1","unstructured":"MAR\u00e9CHAL. The molecular structure of liquid water delivered by absorption spectroscopy in the whole IR region completed with thermodynamics data."},{"issue":"3","key":"e_1_3_6_85_1","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.celrep.2015.06.036","article-title":"Modeling the spatiotemporal dynamics of light and heat propagation for in vivo optogenetics","volume":"12","author":"Stujenske JM","year":"2015","unstructured":"Stujenske JM, Spellman T, Gordon JA. Modeling the spatiotemporal dynamics of light and heat propagation for in vivo optogenetics. Cell Rep. 2015;12(3):525\u2013534.","journal-title":"Cell Rep"},{"issue":"1","key":"e_1_3_6_86_1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/ejn.14251","article-title":"Opto nongenetics inhibition of neuronal firing","volume":"49","author":"Ait Ouares K","year":"2019","unstructured":"Ait Ouares K, Beurrier C, Canepari M, et al. Opto nongenetics inhibition of neuronal firing. Eur J Neurosci. 2019;49(1):6\u201326.","journal-title":"Eur J Neurosci"},{"issue":"7","key":"e_1_3_6_87_1","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1038\/s41593-019-0422-3","article-title":"Thermal constraints on in vivo optogenetic manipulations","volume":"22","author":"Owen SF","year":"2019","unstructured":"Owen SF, Liu MH, Kreitzer AC. Thermal constraints on in vivo optogenetic manipulations. Nat Neurosci. 2019;22(7):1061\u20131065.","journal-title":"Nat Neurosci"},{"key":"e_1_3_6_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2022.12.009"},{"key":"e_1_3_6_89_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-024-01179-1"},{"issue":"1","key":"e_1_3_6_90_1","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s12868-024-00904-w","article-title":"Tinnitus is associated with increased extracellular matrix density in the auditory cortex of Mongolian gerbils","volume":"25","author":"Tziridis K","year":"2024","unstructured":"Tziridis K, Maul A, Rasheed J, et al. Tinnitus is associated with increased extracellular matrix density in the auditory cortex of Mongolian gerbils. BMC Neurosci. 2024;25(1):52.","journal-title":"BMC Neurosci"},{"key":"e_1_3_6_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2020.108003"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2025.2584694","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T08:00:49Z","timestamp":1762761649000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2025.2584694"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":90,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12,31]]}},"alternative-id":["10.1080\/07853890.2025.2584694"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2025.2584694","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,10]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-05-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2584694"}}