{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:56:54Z","timestamp":1789664214763,"version":"4.0.1"},"reference-count":48,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2025,12,31]]},"DOI":"10.1080\/07853890.2025.2588840","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T02:56:43Z","timestamp":1764212203000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":2,"title":["Chlorogenic acid mitigates acute respiratory distress syndrome via inhibition of the PI3K\/AKT signalling pathway: an integrated analysis of bioinformatics and validation experiments"],"prefix":"10.1080","volume":"57","author":[{"given":"Jie","family":"Wei","sequence":"first","affiliation":[{"name":"Departments of Hematology, the First Affiliated Hospital of Guangxi Medical University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guan Ye","family":"Nai","sequence":"additional","affiliation":[{"name":"Departments of hematology, Affiliated Hospital of Youjiang Medical University for Nationalities","place":["Baise, China"]},{"name":"National Immunological Laboratory of Traditional Chinese Medicine","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wu","sequence":"additional","affiliation":[{"name":"Departments of Hematology, the First Affiliated Hospital of Guangxi Medical University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu mei","family":"Huang","sequence":"additional","affiliation":[{"name":"Departments of Hematology, the First Affiliated Hospital of Guangxi Medical University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao Ping","family":"Gan","sequence":"additional","affiliation":[{"name":"Departments of Hematology, the First Affiliated Hospital of Guangxi Medical University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen Bin","family":"Wei","sequence":"additional","affiliation":[{"name":"Departments of Hematology, the First Affiliated Hospital of Guangxi Medical University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit, Baise people\u2019s hospital","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei Jie","family":"Zhou","sequence":"additional","affiliation":[{"name":"Central Laboratory, Baise People\u2019s Hospital","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong rong","family":"Liu","sequence":"additional","affiliation":[{"name":"Departments of Hematology, the First Affiliated Hospital of Guangxi Medical University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.66.9549"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)00757-8"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(18)30345-X"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-014-3354-0"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc053159"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.0291"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2020.12.019"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-021-03463-2"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/v13102090"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1249098"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000381102"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22179612"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2021.107623"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1609183"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.124061"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.13251"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.15.1995"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phyplu.2021.100027"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11655-020-3437-4"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-022-09954-1"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/v13020308"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20190673"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.116946"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-013-3036-3"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2012-0198OC"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI36498"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2014.33"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/crj.13527"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-03148-w"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-022-02065-y"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S321513"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-76122-1"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120389"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02590-2017"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2018.07.005"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano13091438"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.2174\/0118715206357043250116063202"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/13880209.2022.2110599"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10121915"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154474"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1042\/CS20220625"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2021.107530"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155627"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2022.105502"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.7429"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells12121671"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2023.12146"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s11658-022-00308-w"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2025.2588840","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T02:56:44Z","timestamp":1764212204000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2025.2588840"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,26]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12,31]]}},"alternative-id":["10.1080\/07853890.2025.2588840"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2025.2588840","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,26]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-12-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2588840"}}