{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:50:07Z","timestamp":1792792207832,"version":"4.5.0"},"reference-count":45,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Yunnan University of Traditional Chinese Medicine School and Hospital Joint Fund Project","award":["XYLH202352"],"award-info":[{"award-number":["XYLH202352"]}],"id":[{"id":"https:\/\/ror.org\/04zap7912","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2026,12,31]]},"DOI":"10.1080\/07853890.2026.2616886","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T07:35:37Z","timestamp":1768894537000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":5,"title":["Current research hotspots and difficulties of chronic prostatitis\/chronic pelvic pain syndrome: neuroendocrine mechanism"],"prefix":"10.1080","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2609-4618","authenticated-orcid":false,"given":"Bo","family":"Shao","sequence":"first","affiliation":[{"name":"Zhaotong Hospital of Traditional Chinese Medicine, Urology Department","place":["Zhaotong City, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaixiu","family":"Wu","sequence":"additional","affiliation":[{"name":"First Affiliated Medical College, Dali University","place":["Dali City, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengkai","family":"Fan","sequence":"additional","affiliation":[{"name":"Zhaotong Hospital of Traditional Chinese Medicine, Urology Department","place":["Zhaotong City, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingwu","family":"Gao","sequence":"additional","affiliation":[{"name":"Zhaotong Hospital of Traditional Chinese Medicine, Urology Department","place":["Zhaotong City, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shui","family":"Wan","sequence":"additional","affiliation":[{"name":"Urology Department, Wuhu First People\u2019s Hospital","place":["Wuhu City, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Xiao","sequence":"additional","affiliation":[{"name":"Zhaotong Hospital of Traditional Chinese Medicine, Urology Department","place":["Zhaotong City, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanggen","family":"Zuo","sequence":"additional","affiliation":[{"name":"Zhaotong Hospital of Traditional Chinese Medicine, Urology Department","place":["Zhaotong City, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinbo","family":"Pi","sequence":"additional","affiliation":[{"name":"Zhaotong Hospital of Traditional Chinese Medicine, Urology Department","place":["Zhaotong City, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pingping","family":"Sun","sequence":"additional","affiliation":[{"name":"Zhaotong Hospital of Traditional Chinese Medicine, Urology Department","place":["Zhaotong City, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-023-00645-7"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-022-00559-w"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.5173\/ceju.2020.0040"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.14113"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000022151"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41585-018-0135-5"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.56434\/j.arch.esp.urol.20227510.119"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113146"},{"issue":"8","key":"e_1_3_4_10_1","first-page":"681","article-title":"The expression of substance P and c-fos in the spinal cord of rats with chronic prostatitis\/chronic pelvic pain syndrome","volume":"21","author":"Yingjia L","year":"2015","unstructured":"Yingjia L, Guohong S, Chen Z. The expression of substance P and c-fos in the spinal cord of rats with chronic prostatitis\/chronic pelvic pain syndrome. Chinese J Androl. 2015;21(8):681\u2013686.","journal-title":"Chinese J Androl"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-019-1584-3"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/fcp.12517"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.102.032797"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00029330-200709020-00013"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2010.06927.x"},{"issue":"05","key":"e_1_3_4_16_1","first-page":"190","article-title":"Research progress on related factors of pain symptoms of chronic prostatitis in L5-S2 segment of spinal cord","volume":"45","author":"Bin Z","year":"2016","unstructured":"Bin Z, Weiming Z, Youcheng X. Research progress on related factors of pain symptoms of chronic prostatitis in L5-S2 segment of spinal cord. Med Res J. 2016;45(05):190\u2013193.","journal-title":"Med Res J"},{"issue":"08","key":"e_1_3_4_17_1","first-page":"498","article-title":"Determination of calcitonin gene-related peptide expression in spinal dorsal horn of rats with chronic prostatitis","volume":"17","author":"Jinxin C","year":"2011","unstructured":"Jinxin C, Yunxiang L, Anguo W, et al. Determination of calcitonin gene-related peptide expression in spinal dorsal horn of rats with chronic prostatitis. Chinese J Pain Med. 2011;17(08):498\u2013500.","journal-title":"Chinese J Pain Med"},{"issue":"15","key":"e_1_3_4_18_1","first-page":"1925","article-title":"Expression levels of protein kinase G and B-type natriuretic peptide in lumbar 6-sacral 1 dorsal ganglia of rats with chronic nonbacterial prostatitis","volume":"41","author":"Feng L","year":"2019","unstructured":"Feng L, Chengyue W, Yuling Z, et al. Expression levels of protein kinase G and B-type natriuretic peptide in lumbar 6-sacral 1 dorsal ganglia of rats with chronic nonbacterial prostatitis. Guangxi Med. 2019;41(15):1925\u20131929.","journal-title":"Guangxi Med"},{"issue":"06","key":"e_1_3_4_19_1","first-page":"543","article-title":"To explore the biological basis of chronic prostatitis based on the \u2018brain\u2013heart\u2013kidney\u2013seminal chamber\u2019 axis","volume":"29","author":"Ziwei Z","year":"2023","unstructured":"Ziwei Z, Qinghe G, Fu W, et al. To explore the biological basis of chronic prostatitis based on the \u2018brain\u2013heart\u2013kidney\u2013seminal chamber\u2019 axis. Chinese J Androl. 2023;29(06):543\u2013551.","journal-title":"Chinese J Androl"},{"issue":"3","key":"e_1_3_4_20_1","first-page":"204","article-title":"Expressions of BNP and NPR-A in rat models of chronic nonbacterial prostatitis and their significance","volume":"18","author":"Xie WJ","year":"2012","unstructured":"Xie WJ, Sun T, Yang XR. Expressions of BNP and NPR-A in rat models of chronic nonbacterial prostatitis and their significance. Natl Androl. 2012;18(3):204\u2013207.","journal-title":"Natl Androl"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10565-016-9379-0"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/6833867"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2023.05.047"},{"key":"e_1_3_4_24_1","first-page":"13:903250","article-title":"Evaluation of psychological stress, cortisol awakening response, and heart rate variability in patients with chronic prostatitis\/chronic pelvic pain syndrome complicated by lower urinary tract symptoms and erectile dysfunction","author":"Jian B","year":"2022","unstructured":"Jian B, Longjie G, Yinwei C, et al. Evaluation of psychological stress, cortisol awakening response, and heart rate variability in patients with chronic prostatitis\/chronic pelvic pain syndrome complicated by lower urinary tract symptoms and erectile dysfunction. Front Psychol. 2022;13:903250\u201313903250.","journal-title":"Front Psychol"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.09.025"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.10.084"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.07.042"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6687493"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2024.08.009"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.5534\/wjmh.220248"},{"issue":"5","key":"e_1_3_4_31_1","first-page":"403","article-title":"Study on spinal cord infiltration of Th1 and Th17 cells L5-S2 and its central sensitization mechanism in CP\/CPPS model rats","volume":"27","author":"Qinzhou Y","year":"2021","unstructured":"Qinzhou Y, Yi L, Yang S, et al. Study on spinal cord infiltration of Th1 and Th17 cells L5-S2 and its central sensitization mechanism in CP\/CPPS model rats. Chinese J Androl. 2021;27(5):403\u2013409.","journal-title":"Chinese J Androl"},{"issue":"1","key":"e_1_3_4_32_1","first-page":"76","article-title":"The pathogenesis of pain in chronic prostatitis","volume":"22","author":"Hong D","year":"2017","unstructured":"Hong D, Weiming Z. The pathogenesis of pain in chronic prostatitis. Mod J Urol. 2017;22(1):76\u201378.","journal-title":"Mod J Urol"},{"issue":"9","key":"e_1_3_4_33_1","first-page":"352","article-title":"Up-regulated expression of NMDA receptor in the paraventricular nucleus shortens ejaculation latency in rats with experimental autoimmune prostatitis","author":"Jie Y","year":"2020","unstructured":"Jie Y, Qi-Jie Z, Jia-Yi Z, et al. Up-regulated expression of NMDA receptor in the paraventricular nucleus shortens ejaculation latency in rats with experimental autoimmune prostatitis. Andrology. 2020;(9(1):352\u2013360.","journal-title":"Andrology"},{"key":"e_1_3_4_34_1","volume-title":"Sodium butyrate reduces experimental autoimmune prostatitis by inhibiting oxidative stress and NLRP3 inflammasome activation through Nrf2\/HO-1 pathway","author":"Zhang J.","year":"2023","unstructured":"Zhang J. Sodium butyrate reduces experimental autoimmune prostatitis by inhibiting oxidative stress and NLRP3 inflammasome activation through Nrf2\/HO-1 pathway. Anhui Medical University; 2023."},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.JU.0000554003.38258.e0"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/3199988"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e38302"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.915218"},{"issue":"10","key":"e_1_3_4_39_1","first-page":"1736","article-title":"Research progress on the pathogenesis and treatment of chronic prostatitis related to intestinal flora imbalance","volume":"21","author":"Xinyu X","year":"2023","unstructured":"Xinyu X, Yun C, Jun W. Research progress on the pathogenesis and treatment of chronic prostatitis related to intestinal flora imbalance. Chinese Gen Med. 2023;21(10):1736\u20131740.","journal-title":"Chinese Gen Med"},{"key":"e_1_3_4_40_1","first-page":"5521","article-title":"To explore the mechanism of Jingangteng capsule in the treatment of chronic nonbacterial prostatitis based on intestinal flora and metabolomics","author":"Yue X","unstructured":"Yue X, Shiyuan C, Dandan Z, et al. To explore the mechanism of Jingangteng capsule in the treatment of chronic nonbacterial prostatitis based on intestinal flora and metabolomics. Chinese J Trad Chinese Med. 2025,50(19):5521\u20135533.","journal-title":"Chinese J Trad Chinese Med"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2014.04.002"},{"issue":"05","key":"e_1_3_4_42_1","first-page":"136","article-title":"Efficacy and safety of \u03b1-blockers combined with antidepressants in the treatment of chronic prostatitis","volume":"32","author":"Zhongjie L.","year":"2025","unstructured":"Zhongjie L. Efficacy and safety of \u03b1-blockers combined with antidepressants in the treatment of chronic prostatitis. Rare Dis J. 2025;32(05):136\u2013138.","journal-title":"Rare Dis J"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000006243"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10163544"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.15036"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2008.09.074"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2026.2616886","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T07:35:41Z","timestamp":1768894541000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2026.2616886"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,19]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12,31]]}},"alternative-id":["10.1080\/07853890.2026.2616886"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2026.2616886","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,19]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-09-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2616886"}}