{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:46:16Z","timestamp":1791081976586,"version":"4.1.0"},"reference-count":246,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82100763"],"award-info":[{"award-number":["82100763"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hubei Provincial Natural Science Foundation General Program","award":["JCZRYB202500953"],"award-info":[{"award-number":["JCZRYB202500953"]}]},{"name":"Hubei Provincial Natural Science Foundation General Program","award":["2025AF804"],"award-info":[{"award-number":["2025AF804"]}]},{"name":"Hubei Provincial Health Commission Science and Technology Project","award":["WJ2025Q004"],"award-info":[{"award-number":["WJ2025Q004"]}]},{"name":"the China Three Gorges University\u2019s \u2018Bo Yi\u2019 Special Foundation","award":["2025BYZ05"],"award-info":[{"award-number":["2025BYZ05"]}]},{"name":"Open Foundation of Hubei Provincial Key Laboratory of Tumor Microenvironment and Immunotherapy","award":["2025ZLKF02"],"award-info":[{"award-number":["2025ZLKF02"]}]},{"name":"Open Foundation of Hubei Provincial Key Laboratory of Tumor Microenvironment and Immunotherapy","award":["2025ZLKF03"],"award-info":[{"award-number":["2025ZLKF03"]}]},{"name":"Innovation Cultivation Fund for Young-to-Mid-Career Transition of Zhongnan Hospital, Wuhan University","award":["CXPY202514"],"award-info":[{"award-number":["CXPY202514"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2026,12,31]]},"DOI":"10.1080\/07853890.2026.2672141","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T07:46:02Z","timestamp":1779867962000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["Mitophagy in cisplatin-induced kidney injury: regulatory mechanisms and therapeutic targets"],"prefix":"10.1080","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0226-614X","authenticated-orcid":false,"given":"Cheng","family":"Yuan","sequence":"first","affiliation":[{"name":"Department of Oncology, Yichang Central People\u2019s Hospital and The First College of Clinical Medical Science, China Three Gorges University Yichang","place":["Hubei, China"]},{"name":"Tumor Prevention and Treatment Center, Three Gorges University and Cancer Research Institute of Three Gorges University Yichang","place":["Hubei, China"]},{"name":"Clinical Medical Research Center for Precision Diagnosis and Treatment of Lung Cancer and Management of Advanced Cancer Pain of Hubei Province"},{"name":"Central Laboratory, The First College of Clinical Medical Science, China Three Gorges University & Yichang Central People\u2019s Hospital","place":["Yichang, China"]},{"name":"Key Laboratory of Tumor Microenvironment and Immunotherapy of Hubei Province","place":["Yichang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1962-0519","authenticated-orcid":false,"given":"Jinzhou","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Oncology, Yichang Central People\u2019s Hospital and The First College of Clinical Medical Science, China Three Gorges University Yichang","place":["Hubei, China"]},{"name":"Tumor Prevention and Treatment Center, Three Gorges University and Cancer Research Institute of Three Gorges University Yichang","place":["Hubei, China"]},{"name":"Clinical Medical Research Center for Precision Diagnosis and Treatment of Lung Cancer and Management of Advanced Cancer Pain of Hubei Province"},{"name":"Central Laboratory, The First College of Clinical Medical Science, China Three Gorges University & Yichang Central People\u2019s Hospital","place":["Yichang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxing","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Oncology, Yichang Central People\u2019s Hospital and The First College of Clinical Medical Science, China Three Gorges University Yichang","place":["Hubei, China"]},{"name":"Tumor Prevention and Treatment Center, Three Gorges University and Cancer Research Institute of Three Gorges University Yichang","place":["Hubei, China"]},{"name":"Clinical Medical Research Center for Precision Diagnosis and Treatment of Lung Cancer and Management of Advanced Cancer Pain of Hubei Province"},{"name":"Central Laboratory, The First College of Clinical Medical Science, China Three Gorges University & Yichang Central People\u2019s Hospital","place":["Yichang, China"]},{"name":"Key Laboratory of Tumor Microenvironment and Immunotherapy of Hubei Province","place":["Yichang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0456-3279","authenticated-orcid":false,"given":"Lihua","family":"Ni","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tumor Microenvironment and Immunotherapy of Hubei Province","place":["Yichang, China"]},{"name":"Department of Nephrology, Zhongnan Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21731"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1023\/a:1012259625746"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.04800908"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.113373"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2014.07.025"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2018.11.042"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-022-00631-7"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-019-0518-9"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.09.050"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2020.323"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.114150"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-018-0124-1"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/scientificamerican0563-64"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2024.05.012"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1089\/rej.2005.8.3"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2010.02.016"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0911187107"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2021.1888244"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2020104705"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2017.1405880"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.121947"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.15148"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.08.050"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3565(24)36493-6"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2023.113871"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.81406"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00413.x"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.109693"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.08.126"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-017-0012-4"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-023-01151-1"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.116797"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2010.317"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13121534"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-022-00662-0"},{"issue":"9","key":"e_1_3_4_38_1","first-page":"1439","article-title":"Mechanism of action of cis-dichlorodiammineplatinum(II)","volume":"63","author":"Zwelling LA","year":"1979","unstructured":"Zwelling LA, Kohn KW. Mechanism of action of cis-dichlorodiammineplatinum(II). Cancer Treat Rep. 1979;63(9-10):1439\u20131444.","journal-title":"Cancer Treat Rep"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1002565107"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10565-025-10003-z"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27123823"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-018-1152-2"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.020502"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01503-7"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-023-01205-1"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-58189-4"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2016.23"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2017.110"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2275"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3028"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-024-01513-9"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2024.107258"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00064.2017"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-020-09867-x"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.49.070180.002143"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2018.07.011"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-022-00878-x"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2017.107"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-020-00369-0"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2019.101254"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.3390\/life14020196"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0903563106"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddv059"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/33416"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1096284"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-04340-2"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0224-x"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0802076105"},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.240347797"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14893"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1231031"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvx201"},{"key":"e_1_3_4_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12319"},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-1695-x"},{"key":"e_1_3_4_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-019-0260-6"},{"key":"e_1_3_4_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-020-0480-9"},{"key":"e_1_3_4_77_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.1c01921"},{"key":"e_1_3_4_78_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-021-01481-y"},{"key":"e_1_3_4_79_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-017-0016-0"},{"key":"e_1_3_4_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2012.14"},{"key":"e_1_3_4_81_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201540352"},{"key":"e_1_3_4_82_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201489729"},{"key":"e_1_3_4_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13418"},{"key":"e_1_3_4_84_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2019.1656957"},{"key":"e_1_3_4_85_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddu244"},{"key":"e_1_3_4_86_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2023.2234797"},{"key":"e_1_3_4_87_1","doi-asserted-by":"publisher","DOI":"10.5483\/bmbrep.2016.49.8.081"},{"key":"e_1_3_4_88_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.2871"},{"key":"e_1_3_4_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2004.05.009"},{"key":"e_1_3_4_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2014.11.021"},{"key":"e_1_3_4_91_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.303787"},{"key":"e_1_3_4_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2014.139"},{"key":"e_1_3_4_93_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2422"},{"key":"e_1_3_4_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/embr.201438501"},{"key":"e_1_3_4_95_1","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2009.256"},{"key":"e_1_3_4_96_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-01258-6"},{"key":"e_1_3_4_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.11.042"},{"key":"e_1_3_4_98_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201643147"},{"key":"e_1_3_4_99_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI122035"},{"key":"e_1_3_4_100_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvac003"},{"key":"e_1_3_4_101_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.121.319377"},{"key":"e_1_3_4_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-022-00703-y"},{"key":"e_1_3_4_103_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.123.322512"},{"key":"e_1_3_4_104_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.303356"},{"key":"e_1_3_4_105_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2017060659"},{"key":"e_1_3_4_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2014.06.001"},{"key":"e_1_3_4_107_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2012"},{"key":"e_1_3_4_108_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.6.8.13426"},{"key":"e_1_3_4_109_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41421-025-00774-4"},{"key":"e_1_3_4_110_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.124.324285"},{"key":"e_1_3_4_111_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2024.2358732"},{"key":"e_1_3_4_112_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201899360"},{"key":"e_1_3_4_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.05.015"},{"key":"e_1_3_4_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.12.057"},{"key":"e_1_3_4_115_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05722-3"},{"key":"e_1_3_4_116_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1523926113"},{"key":"e_1_3_4_117_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201912144"},{"key":"e_1_3_4_118_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.019310"},{"key":"e_1_3_4_119_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2017.95"},{"key":"e_1_3_4_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2024.10.025"},{"key":"e_1_3_4_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.136119"},{"key":"e_1_3_4_122_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2014.1003478"},{"key":"e_1_3_4_123_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2020.1797280"},{"key":"e_1_3_4_124_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.4600"},{"key":"e_1_3_4_125_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.1.1.1495"},{"key":"e_1_3_4_126_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells14131016"},{"key":"e_1_3_4_127_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.13540"},{"key":"e_1_3_4_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2015.07.021"},{"key":"e_1_3_4_129_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.20284"},{"key":"e_1_3_4_130_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.24001"},{"key":"e_1_3_4_131_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.5338"},{"key":"e_1_3_4_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0891-5849(00)00317-8"},{"key":"e_1_3_4_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/embj.201385902"},{"key":"e_1_3_4_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2014.07.005"},{"key":"e_1_3_4_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.11.005"},{"key":"e_1_3_4_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2019.03.013"},{"key":"e_1_3_4_137_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-025-06283-y"},{"key":"e_1_3_4_138_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2193706"},{"key":"e_1_3_4_139_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.4127"},{"key":"e_1_3_4_140_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9460462"},{"key":"e_1_3_4_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.04.006"},{"key":"e_1_3_4_142_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.115.304384"},{"key":"e_1_3_4_143_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2015.1061849"},{"key":"e_1_3_4_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2015.07.159"},{"key":"e_1_3_4_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.03.006"},{"key":"e_1_3_4_146_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006049"},{"key":"e_1_3_4_147_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-01757-9"},{"key":"e_1_3_4_148_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-382-0_12"},{"key":"e_1_3_4_149_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-021-02178-z"},{"key":"e_1_3_4_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.117006"},{"key":"e_1_3_4_151_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0448-9"},{"key":"e_1_3_4_152_1","doi-asserted-by":"publisher","DOI":"10.1002\/JLB.3MA0320-358RR"},{"key":"e_1_3_4_153_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2563"},{"key":"e_1_3_4_154_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30191"},{"key":"e_1_3_4_155_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2019.1628520"},{"key":"e_1_3_4_156_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00420.2018"},{"key":"e_1_3_4_157_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13672"},{"key":"e_1_3_4_158_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2020.1848971"},{"key":"e_1_3_4_159_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2019-214158"},{"key":"e_1_3_4_160_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.00819"},{"key":"e_1_3_4_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.105956"},{"key":"e_1_3_4_162_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2020.1753002"},{"key":"e_1_3_4_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0092-8674(00)80085-9"},{"key":"e_1_3_4_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0092-8674(00)81266-0"},{"key":"e_1_3_4_165_1","doi-asserted-by":"crossref","unstructured":"Green DR. The mitochondrial pathway of apoptosis part II: the BCL-2 protein family. Cold Spring Harb Perspect Biol. 2022;14(6):a041046. doi: 10.1101\/cshperspect.a041046.","DOI":"10.1101\/cshperspect.a041046"},{"key":"e_1_3_4_166_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.10.046"},{"key":"e_1_3_4_167_1","doi-asserted-by":"publisher","DOI":"10.1038\/348334a0"},{"key":"e_1_3_4_168_1","doi-asserted-by":"publisher","DOI":"10.1038\/335440a0"},{"key":"e_1_3_4_169_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.101469"},{"key":"e_1_3_4_170_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2013.19"},{"key":"e_1_3_4_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2020.105720"},{"key":"e_1_3_4_172_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1059108"},{"issue":"4","key":"e_1_3_4_173_1","doi-asserted-by":"crossref","first-page":"C447","DOI":"10.1152\/ajpcell.00451.2011","article-title":"Denervation-induced mitochondrial dysfunction and autophagy in skeletal muscle of apoptosis-deficient animals","volume":"303","author":"O\u2019Leary MF","year":"2012","unstructured":"O\u2019Leary MF, Vainshtein A, Carter HN, et al. Denervation-induced mitochondrial dysfunction and autophagy in skeletal muscle of apoptosis-deficient animals. Am J Physiol Cell Physiol. 2012;303(4):C447\u201354.","journal-title":"Am J Physiol Cell Physiol"},{"key":"e_1_3_4_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1535-6108(03)00244-7"},{"key":"e_1_3_4_175_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2026.112363"},{"key":"e_1_3_4_176_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-015-0115-9"},{"key":"e_1_3_4_177_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-020-03702-9"},{"key":"e_1_3_4_178_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8527"},{"key":"e_1_3_4_179_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-023-06112-4"},{"key":"e_1_3_4_180_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2017.07.007"},{"key":"e_1_3_4_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2021.113117"},{"key":"e_1_3_4_182_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.12238"},{"key":"e_1_3_4_183_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-013-0895-6"},{"key":"e_1_3_4_184_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-024-01872-0"},{"key":"e_1_3_4_185_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature15514"},{"key":"e_1_3_4_186_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10759"},{"key":"e_1_3_4_187_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0165-0"},{"key":"e_1_3_4_188_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09663"},{"key":"e_1_3_4_189_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2022.05.009"},{"key":"e_1_3_4_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.113974"},{"key":"e_1_3_4_191_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-023-05587-5"},{"key":"e_1_3_4_192_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2010.03.002"},{"key":"e_1_3_4_193_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2021.108640"},{"key":"e_1_3_4_194_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.57825"},{"key":"e_1_3_4_195_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S475915"},{"key":"e_1_3_4_196_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-025-00413-4"},{"key":"e_1_3_4_197_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2023.10.004"},{"key":"e_1_3_4_198_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2023.122293"},{"key":"e_1_3_4_199_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-018-0090-y"},{"key":"e_1_3_4_200_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2025.2487037"},{"key":"e_1_3_4_201_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.03.042"},{"key":"e_1_3_4_202_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-024-00703-5"},{"key":"e_1_3_4_203_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2020.02.009"},{"key":"e_1_3_4_204_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcb.2019.151058"},{"key":"e_1_3_4_205_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202412593"},{"key":"e_1_3_4_206_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2024.09.039"},{"key":"e_1_3_4_207_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2023.02.012"},{"key":"e_1_3_4_208_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-024-01280-y"},{"key":"e_1_3_4_209_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-024-01365-x"},{"key":"e_1_3_4_210_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2023.122162"},{"key":"e_1_3_4_211_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.110801"},{"key":"e_1_3_4_212_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2024.177207"},{"key":"e_1_3_4_213_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-024-00390-0"},{"key":"e_1_3_4_214_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-023-01230-0"},{"key":"e_1_3_4_215_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41421-022-00390-6"},{"key":"e_1_3_4_216_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.113468"},{"key":"e_1_3_4_217_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.112652"},{"key":"e_1_3_4_218_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00709.x"},{"key":"e_1_3_4_219_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483x(89)90105-4"},{"key":"e_1_3_4_220_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V134858"},{"key":"e_1_3_4_221_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200215606"},{"key":"e_1_3_4_222_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V12122683"},{"key":"e_1_3_4_223_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11419"},{"key":"e_1_3_4_224_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.00026.x"},{"key":"e_1_3_4_225_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.66010.x"},{"key":"e_1_3_4_226_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2019.04.035"},{"key":"e_1_3_4_227_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-03431-2"},{"key":"e_1_3_4_228_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483x(88)90143-6"},{"key":"e_1_3_4_229_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2022.102382"},{"key":"e_1_3_4_230_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200910140"},{"key":"e_1_3_4_231_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201402104"},{"key":"e_1_3_4_232_1","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2010.178"},{"key":"e_1_3_4_233_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2725"},{"key":"e_1_3_4_234_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2015.10.014"},{"key":"e_1_3_4_235_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.80775"},{"key":"e_1_3_4_236_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.117097"},{"key":"e_1_3_4_237_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.70014"},{"key":"e_1_3_4_238_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox8050133"},{"key":"e_1_3_4_239_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.768700"},{"key":"e_1_3_4_240_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.44051"},{"key":"e_1_3_4_241_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b01897"},{"key":"e_1_3_4_242_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.08.022"},{"key":"e_1_3_4_243_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2023.01.025"},{"key":"e_1_3_4_244_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2021.10.028"},{"key":"e_1_3_4_245_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-04184-8"},{"key":"e_1_3_4_246_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2016.12.022"},{"key":"e_1_3_4_247_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2025.02.038"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890.2026.2672141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T07:46:05Z","timestamp":1779867965000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890.2026.2672141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,27]]},"references-count":246,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12,31]]}},"alternative-id":["10.1080\/07853890.2026.2672141"],"URL":"https:\/\/doi.org\/10.1080\/07853890.2026.2672141","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,27]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iann20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2026-01-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2672141"}}