{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:39:41Z","timestamp":1779345581819,"version":"3.51.4"},"reference-count":38,"publisher":"Informa UK Limited","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2002,1]]},"DOI":"10.1080\/078538902320772124","type":"journal-article","created":{"date-parts":[[2002,11,1]],"date-time":"2002-11-01T23:31:41Z","timestamp":1036193501000},"page":"380-385","source":"Crossref","is-referenced-by-count":65,"title":["Reduced cystatin B activity correlates with enhanced cathepsin activity in progressive myoclonus epilepsy"],"prefix":"10.1080","volume":"34","author":[{"given":"Riitta","family":"Rinne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pekka","family":"Saukko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikko","family":"J\u00e4rvinen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna-Elina","family":"Lehesjoki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,8]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/j.1600-0404.1974.tb02782.x","volume":"50","author":"Koskiniemi M","year":"1974","journal-title":"Acta Neurol Scand"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"474","DOI":"10.3109\/07853899809002489","volume":"30","author":"Lehesjoki AE","year":"1998","journal-title":"Ann Med"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1600-0404.1969.tb01220.x","volume":"45","author":"Haltia M","year":"1969","journal-title":"Acta Neurol Scand"},{"key":"CIT0005","first-page":"238","volume":"2","author":"Eldridge R","year":"1983","journal-title":"Lancet"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1126\/science.271.5256.1731","volume":"271","author":"Pennacchio LA","year":"1996","journal-title":"Science"},{"key":"CIT0008","first-page":"342","volume":"60","author":"Lalioti MD","year":"1997","journal-title":"Am J Hum Genet"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/386847a0","volume":"386","author":"Lalioti MD","year":"1997","journal-title":"Nature"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/3059","volume":"20","author":"Pennacchio LA","year":"1998","journal-title":"Nat Genet"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1046\/j.1460-9568.2000.00058.x","volume":"12","author":"D'Amato E","year":"2000","journal-title":"Eur J Neurosci"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1042\/bj2360312","volume":"236","author":"Barrett AJ","year":"1986","journal-title":"Biochem J"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/BF02102453","volume":"30","author":"Rawlings ND","year":"1990","journal-title":"J Mol Evol"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"11282","DOI":"10.1016\/S0021-9258(18)67380-6","volume":"261","author":"Abrahamson M","year":"1986","journal-title":"J Biol Chem"},{"key":"CIT0015","first-page":"613","volume":"50","author":"Machleidt W","year":"1991","journal-title":"Biomed Biochim Acta"},{"key":"CIT0016","first-page":"631","volume":"50","author":"Bromme D","year":"1991","journal-title":"Biomed Biochim Acta"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0014-5793(96)00984-2","volume":"395","author":"Lenarcic B","year":"1996","journal-title":"FEBS Lett"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1042\/bj2640467","volume":"264","author":"Kirschke H","year":"1989","journal-title":"Biochem J"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/0076-6879(94)44036-0","volume":"244","author":"Kirschke H","year":"1994","journal-title":"Methods Enzymol"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/978-1-4757-9613-1_33","volume":"421","author":"Kirschke H","year":"1997","journal-title":"Adv Exp Med Biochem"},{"key":"CIT0021","first-page":"113","volume":"379","author":"Yan S","year":"1998","journal-title":"Biol Chem"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1083\/jcb.147.4.775","volume":"147","author":"Driessen C","year":"1999","journal-title":"J Cell Biol"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1126\/science.280.5362.450","volume":"280","author":"Nakagawa T","year":"1998","journal-title":"Science"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1172\/JCI1158","volume":"101","author":"Riese RJ","year":"1998","journal-title":"J Clin Invest"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/BF02815106","volume":"27","author":"Bernstein H-G","year":"1996","journal-title":"Mol Chem Neuropathol"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/BF01614769","volume":"423","author":"Ii K","year":"1993","journal-title":"Virchows Arch A Pathol Anat Histopathol"},{"key":"CIT0027","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1042\/bj3110299","volume":"311","author":"Munger JS","year":"1995","journal-title":"Biochem J"},{"key":"CIT0028","first-page":"573","volume":"75","author":"Rinne A","year":"1981","journal-title":"Verb Anat Ges"},{"key":"CIT0029","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/0167-4838(82)90222-9","volume":"708","author":"J\u00e4rvinen M","year":"1982","journal-title":"Biochim Biophys Acta"},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/0006-291X(85)90216-5","volume":"131","author":"Ritonja A","year":"1985","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0031","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0014-5793(88)80541-6","volume":"239","author":"Jerala R","year":"1988","journal-title":"coli. FEBS Lett"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1042\/bj2180939","volume":"218","author":"Green GD","year":"1984","journal-title":"Biochem J"},{"key":"CIT0033","first-page":"1363","volume":"45","author":"Barrett N","year":"1986","journal-title":"Biomed Biochim Acta"},{"key":"CIT0034","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0076-6879(81)80043-2","author":"Barrett AJ","year":"1981","journal-title":"Methods Enzymol"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/0014-5793(93)80707-2","volume":"334","author":"Shaw E","year":"1993","journal-title":"FEBS Lett"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"16400","DOI":"10.1074\/jbc.273.26.16400","volume":"273","author":"Halfon S, Ford J, Foster J, Dowling L, Lucian L, Sterling M, et al. Leukocystatin, a new class II cystatin expressed selectively by hematopoetic cells","year":"1998","journal-title":"J Biol Chem"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1093\/hmg\/10.18.1867","volume":"10","author":"Lieuallen K, Pennacchio LA, Park M, Myers RM, Lennon GG. Cystatin B-deficient mice have increased expression of apoptosis and glial activation genes","year":"2001","journal-title":"Hum Mol Genet"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1053\/gast.1997.v113.pm9352877","volume":"113","author":"Roberts LR, Kurosawa H, Bronk SF, Fesmier PJ, Agellon LB, Leung WY, et al. cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes","year":"1997","journal-title":"Gastroenterology"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1172\/JCI9914","volume":"106","author":"Guicciardi ME","year":"2000","journal-title":"J Clin Invest"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0065-2571(98)00028-4","volume":"39","author":"Jones B","year":"1999","journal-title":"Adv Enzyme Regul"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/078538902320772124","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,30]],"date-time":"2021-05-30T03:23:42Z","timestamp":1622345022000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1080\/078538902320772124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,1]]},"references-count":38,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2009,7,8]]},"published-print":{"date-parts":[[2002,1]]}},"alternative-id":["10.1080\/078538902320772124"],"URL":"https:\/\/doi.org\/10.1080\/078538902320772124","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,1]]}}}