{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T17:14:06Z","timestamp":1773422046774,"version":"3.50.1"},"reference-count":121,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Medicine"],"published-print":{"date-parts":[[2004,1]]},"DOI":"10.1080\/07853890310024659","type":"journal-article","created":{"date-parts":[[2004,5,7]],"date-time":"2004-05-07T17:43:32Z","timestamp":1083951812000},"page":"172-183","source":"Crossref","is-referenced-by-count":23,"title":["Does leptin link sleep loss and breathing disturbances with major public diseases?"],"prefix":"10.1080","volume":"36","author":[{"given":"Tarja","family":"Saaresranta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olli","family":"Polo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,8]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1146\/annurev.physiol.62.1.413","volume":"62","author":"Ahima RS","year":"2000","journal-title":"Annu Rev Physiol"},{"key":"CIT0002","first-page":"293","volume":"143","author":"Wauters M","year":"2000","journal-title":"Van Gaal LF. Human leptin: from an adipocyte hormone to an endocrine mediator. Eur J Endocrinol"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1056\/NEJM199602013340503","volume":"334","author":"Considine RV","year":"1996","journal-title":"N Engl J Med"},{"key":"CIT0004","first-page":"3424","volume":"81","author":"Rosenbaum M","year":"1996","journal-title":"J Olin Endocrinol Metab"},{"key":"CIT0005","first-page":"342","volume":"46","author":"Montague CT","year":"1997","journal-title":"O'Rahilly S. Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution. Diabetes"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1540285"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1038\/nm0997-1029","volume":"3","author":"Masuzaki H","year":"1997","journal-title":"Nat Med"},{"key":"CIT0008","first-page":"657","volume":"72","author":"Stock SM","year":"1999","journal-title":"Bremme KA. Leptin levels vary significantly during the menstrual cycle, pregnancy, and in vitro fertilization treatment: possible relation to estradiol. Fertil Steril"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1093\/sleep\/20.8.645","volume":"20","author":"Peker Y","year":"1997","journal-title":"Sleep"},{"key":"CIT0010","first-page":"1101","volume":"98","author":"Schwartz MW","year":"1996","journal-title":"Identification of leptin action in rat hypothalamus. J Clin Invest"},{"key":"CIT0011","first-page":"124","volume":"3","author":"Wauters M","year":"1998","journal-title":"Are leptin levels dependent on body fat distribution in obese men and women? Eat Weight Disord"},{"key":"CIT0012","first-page":"90","volume":"86","author":"Heptulla R","year":"2001","journal-title":"J Olin Endocrinol Metab"},{"key":"CIT0013","first-page":"854","volume":"46","author":"Landt M","year":"2000","journal-title":"Wong M. Leptin in cerebrospinal fluid from children: correlation with plasma leptin, sexual dimorphism, and lack of protein binding. Olin Chem"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0168-8227(99)00013-3","volume":"43","author":"Moriya M","year":"1999","journal-title":"Diabetes Res Olin Pract"},{"key":"CIT0015","first-page":"6343","volume":"276","author":"Huang L","year":"2001","journal-title":"Modulation of circulating leptin levels by its soluble receptor. J Biol Chem"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.2337\/diabetes.51.7.2105","volume":"51","author":"Chan JL","year":"2002","journal-title":"Diabetes"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"413","DOI":"10.2337\/diacare.22.3.413","volume":"22","author":"Fox C","year":"1997","journal-title":"Diabetes Care"},{"key":"CIT0018","first-page":"1274","volume":"355","author":"Schuld A","year":"2000","journal-title":"Increased body-mass index in patients with narcolepsy. Lancet"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0899-9007(01)00787-0","volume":"18","author":"Shimizu H","year":"2002","journal-title":"Nutrition"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1172\/JCI119717","volume":"100","author":"Shoeller DA","year":"1997","journal-title":"J Olin Invest"},{"key":"CIT0021","first-page":"29","volume":"139","author":"Mercer JG","year":"1998","journal-title":"Localization of leptin receptor (Ob-R) messenger ribonucleic acid in the rodent hindbrain. Endocrinology"},{"key":"CIT0022","first-page":"41","volume":"243","author":"Shioda S","year":"1998","journal-title":"Immunohistochemical localization of leptin receptor in the rat brain. Neurosci Lett"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0169-328X(00)00167-4","volume":"81","author":"Collin M","year":"2000","journal-title":"Brain Res Mol Brain Res"},{"key":"CIT0024","first-page":"429","volume":"14","author":"Fernandez-Galaz MC","year":"2002","journal-title":"Leptin uptake by serotonergic neurones of the dorsal raphe. J Neuroendocrinol"},{"key":"CIT0026","first-page":"68","volume":"20","author":"Kalra SP","year":"1999","journal-title":"Endocr Rev"},{"key":"CIT0029","first-page":"39","volume":"355","author":"Nishino S","year":"2000","journal-title":"Hypocretin (orexin) deficiency in human narcolepsy. Lancet"},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0167-0115(01)00350-0","volume":"104","author":"Switonska MM","year":"2002","journal-title":"Regul Pept"},{"key":"CIT0031","first-page":"1683","volume":"281","author":"Sierra-Hnigman MR","year":"1998","journal-title":"Biological action of leptin as an angiogenic factor. Science"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.83.10.1059"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0014-2999(90)90618-G","volume":"184","author":"Fletcher PJ","year":"1990","journal-title":"Eur J Pharmacol"},{"key":"CIT0034","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1016\/S0024-3205(99)00649-9","volume":"66","author":"Monti JM","year":"2000","journal-title":"Life Sci"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1152\/jappl.2001.90.4.1247","volume":"90","author":"Nattie EE","year":"2001","journal-title":"J Appl Physiol"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0034-5687(95)00045-F","volume":"101","author":"Bonham AC","year":"1995","journal-title":"Respir Physiol"},{"key":"CIT0038","first-page":"535","volume":"395","author":"Elmquist JK","year":"1998","journal-title":"Distributions of leptin receptor mRNA isoforms in the rat brain. J Comp Neurol"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/BF02244936","volume":"112","author":"Lawton CL","year":"1993","journal-title":"Psycho-pharmacology (Berl)"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1016\/0166-4328(96)00066-6"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1210\/endo.139.1.5675","volume":"139","author":"Harris RB","year":"1998","journal-title":"Endocrinology"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"2820","DOI":"10.1523\/JNEUROSCI.16-08-02820.1996","volume":"16","author":"Portas CM","year":"1996","journal-title":"J Neurosci"},{"key":"CIT0043","first-page":"197","volume":"8","author":"Sinton CM","year":"1999","journal-title":"The effects of leptin on REM sleep and slow wave delta in rats are reversed by food deprivation. J Sleep Res"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0034-5687(98)00050-4","volume":"113","author":"Bernard DG","year":"1998","journal-title":"Respir Physiol"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1113\/jphysiol.1986.sp016290","volume":"380","author":"Lalley PM","year":"1986","journal-title":"J Physiol"},{"key":"CIT0046","first-page":"207","volume":"36","author":"Richerson GB","year":"1995","journal-title":"J Neurophysiol"},{"key":"CIT0048","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1152\/physrev.1992.72.1.165","volume":"72","author":"Jacobs BL","year":"1992","journal-title":"Physiol Rev"},{"key":"CIT0049","doi-asserted-by":"crossref","first-page":"5346","DOI":"10.1523\/JNEUROSCI.15-07-05346.1995","volume":"15","author":"Veasey SC","year":"1995","journal-title":"J Neurosci"},{"key":"CIT0050","first-page":"776","volume":"153","author":"Veasey SC","year":"1996","journal-title":"The effects of serotonin antagonists in animal model of sleep-disordered breathing. Am J Respir Crit Care Med"},{"key":"CIT0051","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1210\/jcem.83.6.4864","volume":"83","author":"Simon C","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1046\/j.1365-2826.2003.01069.x","volume":"15","author":"Mullington JM","year":"2003","journal-title":"J Neuroendocrinol"},{"issue":"1","key":"CIT0054","first-page":"65","volume":"11","author":"Everson CA","year":"2002","journal-title":"J Sleep Res"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.5.9809025"},{"key":"CIT0056","first-page":"716","volume":"81","author":"Tankersley CG","year":"1996","journal-title":"Modified control of breathing in genetically obese (ob\/ ob) mice. J Appl Physiol"},{"key":"CIT0057","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1152\/jappl.1998.85.6.2261","volume":"85","author":"Tankersley CG","year":"1998","journal-title":"J Appl Physiol"},{"key":"CIT0058","first-page":"1155","volume":"1","author":"Maffei M","year":"1995","journal-title":"Ravussin E. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med"},{"key":"CIT0059","first-page":"695","volume":"45","author":"Dagogo- Jack S","year":"1996","journal-title":"Plasma leptin and insulin relationships in obese and non-obese humans. Diabetes"},{"key":"CIT0060","first-page":"984","volume":"45","author":"Klein S","year":"1996","journal-title":"Adipose tissue leptin production and plasma leptin kinetics in humans. Diabetes"},{"key":"CIT0061","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1038\/43185","volume":"387","author":"Montague CT","year":"1997","journal-title":"Nature"},{"key":"CIT0062","first-page":"213","volume":"18","author":"Strobel A","year":"1998","journal-title":"A leptin missense mutation associated with hypogonadism and morbid obesity. Nat Genet"},{"key":"CIT0063","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0002-9343(75)90392-7","volume":"59","author":"Zwillich CW","year":"1975","journal-title":"Am J Med"},{"key":"CIT0064","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/S0140-6736(05)66103-X","volume":"348","author":"Caro JF","year":"1996","journal-title":"Lancet"},{"key":"CIT0065","first-page":"589","volume":"2","author":"Schwartz MW","year":"1996","journal-title":"Porte DJ. Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nat Med"},{"key":"CIT0066","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1046\/j.1365-2265.1997.2441017.x","volume":"47","author":"Hardie L","year":"1997","journal-title":"Clin Endocrinol"},{"key":"CIT0067","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1530\/eje.0.1390198","volume":"139","author":"Mannucci E","year":"1998","journal-title":"Eur J Endocrinol"},{"key":"CIT0068","first-page":"16","volume":"56","author":"Quinton ND","year":"1999","journal-title":"Br J Biomed Sci"},{"key":"CIT0069","first-page":"174","volume":"142","author":"Cella F","year":"2000","journal-title":"Cordera R. Serum leptin concentra-tions during the menstrual cycle in normal-weight women: effects of an oral triphasic estrogen-progestin medication. Eur J Endocrinol"},{"key":"CIT0070","first-page":"36","volume":"7","author":"Di-Carlo C","year":"2000","journal-title":"al. Serum leptin levels in postmenopausal women: effects of transdermal hormone replacement ther-apy. Menopause"},{"key":"CIT0071","first-page":"579","volume":"82","author":"Saad MF","year":"1997","journal-title":"Sexual dimorfism in plasma leptin concentration. J Clin Endocrinol Metab"},{"key":"CIT0072","first-page":"939","volume":"44","author":"Skatrud JB","year":"1978","journal-title":"Kaiser DG. Ventilatory response to medroxyprogesterone acetate in normal subjects: time course and mechanism. J Appl Physiol"},{"key":"CIT0074","first-page":"490","volume":"29","author":"Paolisso G","year":"1999","journal-title":"Lack of association between changes in plasma leptin concentration and food intake during the menstrual cycle. Eur J Clin Invest"},{"key":"CIT0075","first-page":"190","volume":"139","author":"Teirmaa T","year":"1998","journal-title":"Correlation between circulating leptin and luteinizing hor-mone during the menstrual cycle in normal-weight women. Eur J Endocrinol"},{"key":"CIT0078","first-page":"1119","volume":"352","author":"Tsch\u00f6p M","year":"1998","journal-title":"Raised leptin concentrations at high altitude associated with loss of appetite. Lancet"},{"key":"CIT0079","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1136\/thorax.57.1.75","volume":"57","author":"Phipps PR","year":"2002","journal-title":"Thorax"},{"key":"CIT0080","first-page":"1413","volume":"20","author":"Saaresranta T","year":"2002","journal-title":"Effect of medroxyprogester-one acetate on arterial blood gases, serum leptin levels, and neuropeptide Y. Eur Respir J"},{"key":"CIT0081","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1159\/000054587","volume":"72","author":"Shuld A","year":"2000","journal-title":"Neuro-endocrinology"},{"key":"CIT0082","first-page":"805","volume":"87","author":"Kok SW","year":"2002","journal-title":"Reduction of plasma leptin levels and loss of its circadian rhythmicity in hypocretin (orexin)-deficient narcoleptic humans. J Clin Endocrinol Metab"},{"key":"CIT0083","first-page":"608","volume":"163","author":"Bixler E","year":"2001","journal-title":"Prevalence of sleep-disordered breathing in women: effects of gender. Am J Respir Crit Care Med"},{"key":"CIT0084","first-page":"38","volume":"133","author":"Brownell LG","year":"1986","journal-title":"Breathing during sleep in normal pregnant women. Am Rev Respir Dis"},{"key":"CIT0085","first-page":"1448","volume":"120","author":"Maasilta P","year":"2001","journal-title":"Sleep-related disordered breathing during pregnancy in obese women. Chest"},{"key":"CIT0086","first-page":"1622","volume":"174","author":"Nikkola E","year":"1996","journal-title":"Sleep in multiple pregnancy: breathing patterns, oxygenation, and periodic leg movements. Am J Obstet Gynecol"},{"key":"CIT0087","first-page":"H234","volume":"279","author":"Phillips BG","year":"2000","journal-title":"Increases in leptin levels, sympathetic drive, and weight gain in obstructive sleep apnea. Am J Physiol Heart Circ Physiol"},{"key":"CIT0088","first-page":"774","volume":"122","author":"Schafer H","year":"2002","journal-title":"Body fat distribution, serum leptin, and cardiovascular risk factors in men with obstructive sleep apnea. Chest"},{"key":"CIT0089","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1001\/archotol.129.5.538","volume":"129","author":"Ozturk L","year":"2003","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"CIT0090","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/sj.ijo.0801939","volume":"26","author":"Manzella D","year":"2002","journal-title":"Int J Obes"},{"key":"CIT0091","first-page":"656","volume":"344","author":"Polo","year":"1994","journal-title":"Man-agement of obstructive sleep apnoea\/hypopnoea syndrome. Lancet"},{"key":"CIT0094","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1161\/01.CIR.100.7.706","volume":"100","author":"Chin K","year":"1999","journal-title":"Circulation"},{"key":"CIT0095","first-page":"580","volume":"118","author":"Ip MS","year":"2000","journal-title":"Serum leptin and vascular risk factors in obstructive sleep apnea. Chest"},{"key":"CIT0096","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1136\/thorax.57.5.429","volume":"57","author":"Shimizu K","year":"2002","journal-title":"Thorax"},{"key":"CIT0097","first-page":"375","volume":"25","author":"Saini J","year":"1993","journal-title":"Effects on growth hormone, insulin and glucose profiles in obstructive sleep apnea patients. Horm Metab Res"},{"key":"CIT0098","first-page":"172","volume":"18","author":"Cooper BG","year":"1995","journal-title":"Hormonal and metabolic profiles in subjects with obstructive sleep apnea syndrome and the effects of nasal continuous positive airway pressure (CPAP) treatment. Sleep"},{"key":"CIT0099","doi-asserted-by":"crossref","first-page":"S218","DOI":"10.1093\/sleep\/19.suppl_10.S218","volume":"19","author":"Grunstein RR","year":"1996","journal-title":"Sleep"},{"key":"CIT0101","first-page":"798","volume":"87","author":"Randeva HS","year":"2002","journal-title":"Differential effects of GH replacement on the components of the leptin system in GH-deficient individuals. J Clin Endocrinol Metab"},{"key":"CIT0102","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1164\/ajrccm.160.4.9811033","volume":"160","author":"Schols AM","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"CIT0104","first-page":"1239","volume":"162","author":"Creutzberg EC","year":"2000","journal-title":"Disturbances in leptin metab-olism are related to energy imbalance during acute exacer-bations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med"},{"key":"CIT0105","doi-asserted-by":"crossref","first-page":"R905","DOI":"10.1152\/ajpregu.2000.278.4.R905","volume":"278","author":"Everson CA","year":"2000","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"CIT0106","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1096\/fasebj.10.5.8621064","volume":"10","author":"Irwin M","year":"1996","journal-title":"FASEB J"},{"key":"CIT0107","first-page":"4018","volume":"168","author":"Mancuso P","year":"2002","journal-title":"Leptin-deficient mice exhibit impaired host defence in gram-negative pneumonia. J Immunol"},{"key":"CIT0108","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s004060170057","volume":"251","author":"Dahmen N","year":"2001","journal-title":"Increased prevalence of obesity in narcoleptic patients and relatives. Eur Arch Psychiatry Clin Neurosci"},{"key":"CIT0109","first-page":"1435","volume":"354","author":"Spiegel K","year":"1999","journal-title":"Impact of sleep debt on metabolic and endocrine function. Lancet"},{"key":"CIT0110","first-page":"A105","volume":"25","author":"Ryden AM","year":"2002","journal-title":"Sleep in type II diabetes: a survey study. Sleep"},{"key":"CIT0111","first-page":"239","volume":"47","author":"Chessler SD","year":"1998","journal-title":"Increased plasma leptin levels are associated with fat accu-mulation in Japanese Americans. Diabetes"},{"key":"CIT0112","first-page":"988","volume":"45","author":"Segal KR","year":"1996","journal-title":"Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. Diabetes"},{"key":"CIT0113","first-page":"4","volume":"1","author":"Lichnovska R","year":"2002","journal-title":"Gender differences in factors influencing insulin resistance in elderly hyperlipemic non-diabetic subjects. Cardiovasc Diabetol"},{"key":"CIT0115","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2337\/diacare.22.1.65","volume":"22","author":"McNeely MJ","year":"1999","journal-title":"Diabetes Care"},{"key":"CIT0116","doi-asserted-by":"crossref","first-page":"3052","DOI":"10.1161\/hc5001.101061","volume":"104","author":"Wallace AM","year":"2001","journal-title":"Circulation"},{"key":"CIT0117","first-page":"533","volume":"245","author":"Soderberg S","year":"1999","journal-title":"Plasma leptin levels are associated with abnormal fibrinolysis in men and postmenopausal women. J Intern Med"},{"key":"CIT0118","first-page":"328","volume":"30","author":"Soderberg S","year":"1999","journal-title":"Leptin as a risk marker for first-ever hemorrhagic stroke in a population-based cohort. Stroke"},{"key":"CIT0119","first-page":"1577","volume":"8","author":"Asikainen M","year":"1997","journal-title":"Sleep deprivation increases brain serotonin turnover in the rat. Neuroreport"},{"key":"CIT0120","first-page":"2685","volume":"85","author":"Chin-Chance C","year":"2000","journal-title":"Twenty-four-hour leptin levels respond to cumulative short-term energy imbalance and predict subsequent intake. J Clin Endocrinol Metab"},{"key":"CIT0121","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1038\/sj.ijo.0801028","volume":"23","author":"van Amelsvoort LG","year":"1999","journal-title":"Duration of shiftwork related to body mass index and waist hip ratio. Int J Obes Relat Metab Disord"},{"key":"CIT0122","first-page":"27","volume":"16","author":"Geliebter A","year":"2000","journal-title":"Work-shift period and weight change. Nutrition"},{"key":"CIT0124","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0166-4328(95)00020-T","volume":"69","author":"Rechtschaffen A","year":"1995","journal-title":"Behav Brain Res"},{"key":"CIT0125","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/sleep\/9.1.254","volume":"9","author":"Honda Y","year":"1986","journal-title":"Sleep"},{"key":"CIT0126","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1038\/nm0297-238","volume":"3","author":"Ravussin E","year":"1997","journal-title":"Nat Med"},{"key":"CIT0127","doi-asserted-by":"crossref","first-page":"232","DOI":"10.2337\/diacare.16.1.232","volume":"16","author":"Ravusssin E","year":"1993","journal-title":"Studies in the Pima Indians. Diabetes Care"},{"key":"CIT0128","doi-asserted-by":"crossref","first-page":"547","DOI":"10.2337\/diacare.26.2.547","volume":"26","author":"Sayeed MA","year":"2003","journal-title":"Diabetes Care"},{"key":"CIT0129","first-page":"533","volume":"54","author":"Lewandowski K","year":"2001","journal-title":"Effects of insulin and glucocorticoids on the leptin system are mediated through free leptin. Clin Endocrinol Oxf"},{"key":"CIT0130","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.2337\/diacare.22.7.1092","volume":"22","author":"Donahue RP","year":"1999","journal-title":"Diabetes Care"},{"key":"CIT0131","first-page":"1293","volume":"82","author":"Kennedy A","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"CIT0132","first-page":"619","volume":"14","author":"Corica F","year":"2001","journal-title":"Leptin and norepinephrine plasma concentrations during glucose loading in normotensive and hypertensive obese women. Am J Hypertens"},{"key":"CIT0134","first-page":"1471","volume":"288","author":"Spiegel K","year":"2002","journal-title":"Effect of sleep depriva-tion on response to immunization. JAMA"},{"key":"CIT0136","first-page":"4139","volume":"82","author":"Donahoo WT","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"CIT0137","first-page":"407","volume":"48","author":"Pinkney JH","year":"1998","journal-title":"Effect of iso-prenaline on plasma leptin and lipolysis in humans. Clin Endocrinol (Oxf)"},{"key":"CIT0138","first-page":"995","volume":"55","author":"Newcomer JW","year":"1998","journal-title":"Dose-dependent cortisol-induced increases in plasma leptin concentration in healthy humans. Arch Gen Psychiatry"}],"container-title":["Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/07853890310024659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,5,14]],"date-time":"2018-05-14T07:23:18Z","timestamp":1526282598000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1080\/07853890310024659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1]]},"references-count":121,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2009,7,8]]},"published-print":{"date-parts":[[2004,1]]}},"alternative-id":["10.1080\/07853890310024659"],"URL":"https:\/\/doi.org\/10.1080\/07853890310024659","relation":{},"ISSN":["0785-3890","1365-2060"],"issn-type":[{"value":"0785-3890","type":"print"},{"value":"1365-2060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,1]]}}}