{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T22:41:47Z","timestamp":1773096107224,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,1,2]],"date-time":"2007-01-02T00:00:00Z","timestamp":1167696000000},"content-version":"vor","delay-in-days":2527,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2000,2]]},"abstract":"<jats:p>We investigated the effect of <jats:italic>Helicobacter pylori<\/jats:italic> eradication on sideropenic refractory anaemia in adolescent girls with <jats:italic>H. pylori<\/jats:italic>\u2010associated antral gastritis without evidence of haemorrhage or clinical symptoms other than sideropenic anaemia. We conducted an open therapeutic trial in 21 adolescent girls aged 15\u201317 y with sideropenic refractory anaemia, which was defined as iron\u2010deficiency anaemia refractory to oral iron therapy for 3 mo. All subjects underwent gastroduodenal endoscopy. Thirteen patients with confirmed <jats:italic>H. pylori<\/jats:italic> infection were given a 2\u2010wk course of triple therapy and 6 wk of oral ferrous sulfate. We compared the mean levels of haemoglobin and serum ferritin among the \u201cinitial sample\u201d (the time when the sampling was done before treatment with oral iron),\u201cbefore eradication\u201d (the time prior to triple therapy for eradication after subjects had been given oral iron for 3 mo) and \u201cafter eradication\u201d (the time when the follow\u2010up endoscopy was performed) data in 11 subjects in whom <jats:italic>H. pylori<\/jats:italic> infection was eradicated. Haemoglobin levels (g\/dl) were 8.6 \u00b11.9, 8.6 \u00b11.4 and 11.3 \u00b12.3, respectively. Serum ferritin levels (p.g\/l) were 4.6 \u00b1 2.4, 4.2 \u00b1 2.3 and 17.5 \u00b1 6.7, respectively. After eradication of <jats:italic>H. pylori<\/jats:italic>, mean levels of haemoglobin (<jats:italic>p =<\/jats:italic> 0.0002) and serum ferritin (<jats:italic>p =<\/jats:italic> 0.0002) showed a prominent increase between \u201cbefore eradication\u201d and \u201cafter eradication\u201d. In conclusion, adolescent girls with sideropenic refractory anaemia should be evaluated for <jats:italic>H. pylori<\/jats:italic> infection. If <jats:italic>H. pylori<\/jats:italic> infection is coexistent, its eradication along with iron supplementation could correct the anaemia.<\/jats:p>","DOI":"10.1111\/j.1651-2227.2000.tb01208.x","type":"journal-article","created":{"date-parts":[[2010,8,7]],"date-time":"2010-08-07T00:52:20Z","timestamp":1281142340000},"page":"154-157","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Effect of Helicobacter pylori eradication on sideropenic refractory anaemia in adolescent girls with Helicobacter pylori infection"],"prefix":"10.1111","volume":"89","author":[{"given":"Yh","family":"Choe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Je","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sk","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,2]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.27.8.1870-1873.1989"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(92)91782-Y"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199308000-00018"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529709025109"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199901000-00027"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03540380049030"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-5378.1999.98066.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.61.6.2694-2697.1993"},{"key":"e_1_2_1_10_2","first-page":"974","article-title":"Iatrogenic Campylobacter pylori infection is a cause of epidemic achlorhydria","volume":"83","author":"Graham DY","year":"1986","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199311000-00023"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.34.020183.000415"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1651-2227.2000.tb01208.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1651-2227.2000.tb01208.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1651-2227.2000.tb01208.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T15:02:32Z","timestamp":1693580552000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1651-2227.2000.tb01208.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,2]]},"references-count":11,"aliases":["10.1080\/080352500750028753"],"journal-issue":{"issue":"2","published-print":{"date-parts":[[2000,2]]}},"alternative-id":["10.1111\/j.1651-2227.2000.tb01208.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1651-2227.2000.tb01208.x","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,2]]},"assertion":[{"value":"2007-01-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}