{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:15:10Z","timestamp":1761016510148},"reference-count":19,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2007,3,29]],"date-time":"2007-03-29T00:00:00Z","timestamp":1175126400000},"content-version":"vor","delay-in-days":118,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p> <jats:italic>Aim:<\/jats:italic> To study the outcome of staged palliation for classic hypoplastic left heart syndrome. <jats:italic>Methods:<\/jats:italic> Retrospective chart review. Risk factors for mortality were analysed using Cox's proportional hazard regression modelling. <jats:italic>Results:<\/jats:italic> From 1993 to 2004, 55 infants underwent Norwood stage I procedure at a median age of 8 d (range 1\u201319 d). Hospital survival was 39\/55 (71%), and there were six late deaths (before stage II). Birthweight, circulatory arrest time and cardiopulmonary bypass time were independent risk factors for stage I hospital mortality (<jats:italic>p<\/jats:italic>=0.029, <jats:italic>p<\/jats:italic>=0.001 and <jats:italic>p<\/jats:italic>=0.003, respectively). Poor right ventricular function prior to stage I was a significant predictor for interstage mortality (<jats:italic>p<\/jats:italic>=0.02). Thirty\u2010two patients underwent bidirectional cavopulmonary anastomosis, at a median age of 6.5 mo (range 2.0\u20139.5 mo), with seven late deaths. Two patients had a heart transplant after stage II. Total cavopulmonary connection (TCPC) was performed in 13 patients, at a median age of 33 mo (range 21\u201345 mo), without mortality. Kaplan\u2010Meier survival was 58%, 52% and 45% at 6, 12 and 48 mo, respectively.<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> Low birthweight, long time on circulatory arrest and cardiopulmonary bypass were risk factors for stage I mortality. Poor right ventricular function was detrimental to intermediate outcome.<\/jats:p>","DOI":"10.1080\/08035250600647070","type":"journal-article","created":{"date-parts":[[2006,5,5]],"date-time":"2006-05-05T13:59:16Z","timestamp":1146837556000},"page":"1594-1600","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Results of staged palliation for hypoplastic left heart syndrome: A complete population\u2010based series"],"prefix":"10.1111","volume":"95","author":[{"given":"BORIS","family":"NILSSON","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MATS","family":"MELLANDER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00d6RAN","family":"S\u00dcDOW","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00c5KAN","family":"BERGGREN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,3,29]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)30727-1"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(80)90224-6"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002469900314"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(99)70373-9"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(99)00155-4"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.suppl_3.III-136"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(02)00198-7"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(03)00343-6"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(03)00072-1"},{"key":"e_1_2_6_11_2","doi-asserted-by":"crossref","first-page":"II155","DOI":"10.1161\/01.cir.0000087390.94142.1d","article-title":"Right ventricle to pulmonary artery conduit improves outcome after stage I Norwood for hypoplastic left heart syndrome","volume":"108","author":"Pizarro C","year":"2003","journal-title":"Circulation"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(03)00389-1"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2005.01.061"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(95)00848-9"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(99)00590-1"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2001.116948"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00313-5"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)01131-0"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.9.262"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(00)02324-9"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1080%2F08035250600647070","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1080\/08035250600647070","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T12:30:40Z","timestamp":1697373040000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1080\/08035250600647070"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":19,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1080\/08035250600647070"],"URL":"https:\/\/doi.org\/10.1080\/08035250600647070","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,12]]},"assertion":[{"value":"2007-03-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}