{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T10:58:29Z","timestamp":1792839509637,"version":"4.5.0"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,1,2]],"date-time":"2007-01-02T00:00:00Z","timestamp":1167696000000},"content-version":"vor","delay-in-days":3137,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[1998,6]]},"abstract":"<jats:p>Of 18 newborn infants found to have persistent galactosaemia and without enzyme deficiencies, intrahepatic porto\u2010venous (P\u2010V) shunts were the cause in 8 cases. We retrospectively analysed the clinical and biochemical features of the eight infants. Four patients received prednisolone, one of whom with heart failure owing to arteriovenous shunts also underwent hepatic arterial embolization. The other four patients were merely observed without receiving drug therapy. Regardless of treatment, the P\u2010V shunts disappeared in five infants before the age of 1 y and persisted in three others. All infants showed mild or moderate abnormalities in liver function tests. None exhibited hyperammonemia or neuropsychiatric symptoms related to the shunts. The data indicated that the prognosis of infants with intrahepatic P\u2010V shunts is generally good. In the absence of complications related to the P\u2010V shunts, no treatment other than galactose elimination diet is indicated.<\/jats:p>","DOI":"10.1111\/j.1651-2227.1998.tb01521.x","type":"journal-article","created":{"date-parts":[[2010,8,7]],"date-time":"2010-08-07T02:00:22Z","timestamp":1281146422000},"page":"631-634","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Clinical features and outcome of eight infants with intrahepatic porto\u2010venous shunts detected in neonatal screening for galactosaemia"],"prefix":"10.1111","volume":"87","author":[{"given":"H","family":"Ono","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Mawatari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Mizoguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Eguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Sakura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,2]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01957721"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01957722"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01957222"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004310050697"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.139.5.1013"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)80341-5"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1007\/BF02773819","article-title":"Intrahepatic portal\u2010systemic shunt: its etiology and diagnosis","volume":"22","author":"Horiguchi Y","year":"1987","journal-title":"Gastroenterol Jpn"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/S0016-5085(24)05148-5","article-title":"Spontaneous portal\u2010hepatic venous shunt via an intrahepatic portal vein aneurysm","volume":"86","author":"Takayasu K","year":"1984","journal-title":"Gastroenterology"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2944(71)90036-6"},{"key":"e_1_2_1_11_2","first-page":"497","article-title":"Uridine diphosphate galactose 4\u2010 epimerase deficiency","volume":"28","author":"Gitzelmann R","year":"1973","journal-title":"Helv Paediat Acta"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0076-6879(66)09144-4"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(93)90147-V"},{"key":"e_1_2_1_14_2","first-page":"2","article-title":"Diagnostic and therapeutic significance of urinary galactitol in neonates with hypergalactosaemia (in Japanese with English abstract)","volume":"101","author":"Sakura N","year":"1997","journal-title":"J Jpn Pediatr Soc"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(96)70446-8"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1651-2227.1998.tb01521.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1651-2227.1998.tb01521.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T22:40:58Z","timestamp":1740350458000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1651-2227.1998.tb01521.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,6]]},"references-count":14,"aliases":["10.1080\/080352598750014021"],"journal-issue":{"issue":"6","published-print":{"date-parts":[[1998,6]]}},"alternative-id":["10.1111\/j.1651-2227.1998.tb01521.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1651-2227.1998.tb01521.x","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,6]]},"assertion":[{"value":"2007-01-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}