{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:09:42Z","timestamp":1790723382026,"version":"4.1.0"},"reference-count":48,"publisher":"Informa UK Limited","issue":"1-2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Ophthalmology"],"published-print":{"date-parts":[[2004,1]]},"DOI":"10.1080\/08820530490884173","type":"journal-article","created":{"date-parts":[[2004,11,22]],"date-time":"2004-11-22T17:16:00Z","timestamp":1101143760000},"page":"62-68","source":"Crossref","is-referenced-by-count":51,"title":["Evolution of retinal laser therapy: minimum intensity photocoagulation (MIP). Can the laser heal the retina without harming it?"],"prefix":"10.1080","volume":"19","author":[{"given":"Giorgio","family":"Dorin","sequence":"first","affiliation":[{"name":"IRIDEX Corporation Mountain View California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2009,7,2]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-200408000-00002"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1001\/archopht.1991.01080110085041","article-title":"Mc Donald HR et al. Progressive enlargement of laser scars following grid laser photocoag- ulation for diffuse diabetic macular edema","volume":"109","author":"Shatz H","year":"1991","unstructured":"Shatz H, Madeira D, Mc Donald HR et al. Progressive enlargement of laser scars following grid laser photocoag- ulation for diffuse diabetic macular edema. Arch Ophthal- mol. 1991;109:1549\u20131551.","journal-title":"Arch Ophthal- mol"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(89)32924-1"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.10.1099"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-0622"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1364\/JOSA.60.000264"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/08820539909069538"},{"key":"e_1_2_1_9_1","unstructured":"Schushereba ST Bowman PD Stuck BE. Protection of ARPE-19 cells against thermal injury: Evaluation of thermal preconditioning and Herbimycin A treatment by cell viability and cDNA arrays. Invest Ophthal Vis Sci . 2003;44: ARVOE-Abstract 2281."},{"key":"e_1_2_1_10_1","unstructured":"Midena E de Belvis V Lo Giudice G Pilotto E Piermarocchi S. Transpupillary thermotherapy of retinal angiomatous proliferation in age-related macular degener- ation. Invest Ophthal Vis Sci . 2002;43: ARVOE-Abstract 4417."},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"359","DOI":"10.3928\/1542-8877-20000901-03","article-title":"Transpupillary thermotherapy: Long-pulse photocoagulation, apoptosis and heat shock proteins","volume":"31","author":"Mainster MA","year":"2000","unstructured":"Mainster MA, Reichel E. Transpupillary thermotherapy: Long-pulse photocoagulation, apoptosis and heat shock proteins. Ophthalmic Surg Lasers. 2000;31:359\u2013373.","journal-title":"Ophthalmic Surg Lasers"},{"key":"e_1_2_1_12_1","unstructured":"Ito Y Yoneya S Takita H Ito M Mori K. Upregulation of antiangiogenic genes by transpupillary thermotherapy. Invest Ophthal Vis Sci . 2004;45: ARVOE-Abstract 706."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-0716"},{"key":"e_1_2_1_14_1","unstructured":"Pirozzi E Coccimiglio F Manganelli C et al . Retinal func- tion following transpupillary thermotherapy for occult choroidal neovascularization in age-related macular degen- eration: a short-term study by focal ERGs. Invest Ophthal Vis Sci . 2004;45: ARVOE-Abstract 5128."},{"key":"e_1_2_1_15_1","unstructured":"Midena E Radin P Pilotto E Maritan V Piermarocchi S. Macular subthreshold transpupillary thermotherapy does not impair macular function. Invest Ophthal Vis Sci . 2003;44: ARVOE-Abstract 1785."},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90400-1"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.85.2.173"},{"issue":"2","key":"e_1_2_1_18_1","first-page":"66","author":"Park CH","unstructured":"Park CH, Duker JS, Mainster MA, Puliafito CA, Reichel E. Transpupillary thermotherapy (TTT) of occult choroidal neovascularization: A retrospective, noncomparative case series of fifty-seven eyes. Semin Ophthlamol. 2001;16(2): 66\u201369.","journal-title":"Semin Ophthlamol"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1076\/soph.16.2.70.4207"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1076\/soph.16.2.81.4215"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1076\/soph.16.2.86.4212"},{"key":"e_1_2_1_22_1","doi-asserted-by":"crossref","unstructured":"Thach AB Sipperley JO Dugel PU Sneed SR Park DW Cornelius J. Large-spot size transpupillary thermotherapy for the treatment of occult choroidal neovascularization associated with age-related macular degeneration. Arch Ophthalmol . 2003;121(6);817\u2013820.","DOI":"10.1001\/archopht.121.6.817"},{"key":"e_1_2_1_23_1","volume-title":"Acta Ophthalmol Scand","author":"Algvere PV","unstructured":"Algvere PV, Libert C, Lindg\u00e4rde G, Seregard S. Transpupil- lary thermotherapy of predominantly occult choroidal neo- vascularization in age-related macular degeneration with 12 months follow-up. Acta Ophthalmol Scand. 2003;81:110\u2013 117."},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1076\/soph.16.2.90.4210"},{"key":"e_1_2_1_25_1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1046\/j.1600-0420.2004.00217.x","article-title":"Transpupillary ther- motherapy for idiopathic subfoveal choroidal neovascular- ization","volume":"82","author":"Kumar A","year":"2004","unstructured":"Kumar A, Prakash G, Singh RP. Transpupillary ther- motherapy for idiopathic subfoveal choroidal neovascular- ization. Acta Ophthalmol Scan. 2004;82:205\u2013208.","journal-title":"Acta Ophthalmol Scan"},{"key":"e_1_2_1_26_1","first-page":"35","article-title":"Transpupillary thermotherapy in subfoveal choroidal neo- vascular membrane secondary to age-related macular degeneration","volume":"52","author":"Verma L","year":"2004","unstructured":"Verma L, Tewari HK, Nainiwal S, Ravindranathan J. Transpupillary thermotherapy in subfoveal choroidal neo- vascular membrane secondary to age-related macular degeneration. Indian J Ophthalmol. 2004;52:35\u201340.","journal-title":"Indian J Ophthalmol"},{"key":"e_1_2_1_27_1","first-page":"45","volume":"52","author":"Agarwal M","year":"2004","unstructured":"Agarwal M, Shanmugam MP, Gopal L et al. Transpupillary thermotherapy for choroidal neovascular membrane in age- related macular degeneration. Indian J Ophthalmol. 2004;52:45\u201349.","journal-title":"Indian J Ophthalmol"},{"key":"e_1_2_1_28_1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3928\/1542-8877-20040501-06","volume":"35","author":"Sharma T","year":"2004","unstructured":"Sharma T, Shah N, Gopal L et al. Indocyanine green dye- enhanced transpupillary thermotherapy of classic subfoveal choroidal neovascularization. Ophthalmic Surg Lasers Imaging. 2004;35:197\u2013206.","journal-title":"Ophthalmic Surg Lasers Imaging"},{"key":"e_1_2_1_29_1","unstructured":"Hamon F Salvetti P Goeminne P Cardoen L. Modified transpupillary thermotherapy (TTT) for submacular serous detachment in chronic serous choroidopathy (CSC). Invest Ophthal Vis Sci . 2004;45: ARVOE-Abstract 531."},{"key":"e_1_2_1_30_1","unstructured":"Takasu I Shiraga F Hosoki M Okabe H Ohtsuki H. Transpupillary thermotherapy for chronic central serous chorioretinopathy. Invest Ophthal Vis Sci . 2004;45: ARVOE-Abstract 533."},{"key":"e_1_2_1_31_1","unstructured":"Sivagnanavel V Chong V. Diffuse laser for drusen reduc- tion in high risk age-related maculopathy. Invest Ophthal Vis Sci . 2004;45: ARVOE-Abstract 3097."},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90487-6"},{"key":"e_1_2_1_33_1","volume-title":"Ophthalmic Surg Lasers","author":"Akduman L","unstructured":"Akduman L, Olk RJ. Subthreshold (invisible) modified grid diode laser photocoagulation in diffuse diabetic macular edema (DDME). Ophthalmic Surg Lasers. 1999;30:706\u2013 714."},{"issue":"1","key":"e_1_2_1_34_1","first-page":"25","article-title":"Minimal intensity diode laser (810 nanometer) photocoagulation (MIP) for diffuse diabetic macular edema (DDME)","author":"Olk RJ","unstructured":"Olk RJ, Akduman L. Minimal intensity diode laser (810 nanometer) photocoagulation (MIP) for diffuse diabetic macular edema (DDME). Semin Ophthalmol. 2001;16(1): 25\u201330.","journal-title":"Semin Ophthalmol"},{"key":"e_1_2_1_35_1","volume-title":"Semin Ophthalmol","author":"Dorin G.","unstructured":"Dorin G. Subthreshold and micropulse diode laser photocoagulation. Semin Ophthalmol. 2003;18(3):147\u2013 143."},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(97)30061-X"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1999.41"},{"key":"e_1_2_1_38_1","doi-asserted-by":"crossref","unstructured":"Stanga PE Reck AC Hamilton AMP. Micropulse laser in the treatment of diabetic macular edema. Semin Ophthal- mol . 1999;14(4);210\u2013213.","DOI":"10.3109\/08820539909069539"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2003.040949"},{"key":"e_1_2_1_40_1","unstructured":"Luttrull JK Musch DC Mainster MA. Subvisible diode micropulse photocoagulation for the treatment of clinically significant macular edema. Br J Ophthalmol . 2004;88 (in press)."},{"key":"e_1_2_1_41_1","unstructured":"Grigorian RA Zarbin MA Brimacombe R Tutela A Roy M Bhagat N. Comparison of subthreshold micropulse diode laser photocoagulation with conventional laser pho- tocoagulation for clinically significant macular edema in diabetic patients. Invest Ophthal Vis Sci . 2004;45: ARVOE-Abstract 4067."},{"key":"e_1_2_1_42_1","unstructured":"Avery RL Pieramici DJ Nasir MA Rhodes K Robbins E. Micropulse laser for diabetic macular edema: A prospec- tive pilot study. Invest Ophthal Vis Sci . 2004;45: ARVOE- Abstract 4143."},{"key":"e_1_2_1_43_1","unstructured":"McHugh JA Tandon A el-Ghonemy K. Micropulsed diode laser for diabetic macular edema. Invest Ophthal Vis Sci . 2002;43: ARVOE-Abstract 562."},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1076\/soph.16.1.19.4217"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1177\/112067210401400115"},{"key":"e_1_2_1_46_1","unstructured":"Bandello F Lanzetta P Furlan F Polito A. Micropulse diode laser treatment of idiopatic central serous chorioretinopa- thy. A pilot study. Invest Ophthal Vis Sci . 2003;44: ARVOE-Abstract 4858."},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1076\/soph.16.1.8.4216"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)01691-4"},{"key":"e_1_2_1_49_1","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3928\/1542-8877-20030101-10","article-title":"Subthreshold infrared foot-printing with indocyanine green for localizing low- intensity infrared photocoagulation","volume":"34","author":"Salvetti P","year":"2003","unstructured":"Salvetti P, Rosen JM, Reichel E. Subthreshold infrared foot-printing with indocyanine green for localizing low- intensity infrared photocoagulation. Ophthalmic Surg Lasers Imaging. 2003;34:44\u201348.","journal-title":"Ophthalmic Surg Lasers Imaging"}],"container-title":["Seminars in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/08820530490884173","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T12:13:51Z","timestamp":1753100031000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/08820530490884173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1]]},"references-count":48,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2004,1]]}},"alternative-id":["10.1080\/08820530490884173"],"URL":"https:\/\/doi.org\/10.1080\/08820530490884173","relation":{},"ISSN":["0882-0538","1744-5205"],"issn-type":[{"value":"0882-0538","type":"print"},{"value":"1744-5205","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,1]]}}}