{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:05:21Z","timestamp":1784030721487,"version":"3.55.0"},"reference-count":14,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Substance Abuse"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The purpose of this study was to compare demographic factors and 1-year treatment outcomes of patients treated with buprenorphine or methadone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study included 252 subjects who received a prescription for buprenorphine in an academic internal medicine practice and 252 subjects who enrolled in a methadone maintenance program located on the same campus over the same time frame. Data were collected retrospectively. Patients were classified as \u201copioid-positive\u201d or \u201copioid-negative\u201d each month for a year based on urine drug testing and provider assessment. Successful treatment was defined as remaining in treatment after 1 year and achieving 6 or more opioid-negative months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Buprenorphine patients were more likely to be male, have health insurance, be employed, abuse prescription opioids, and be human immunodeficiency virus (HIV) infected; they were less likely to abuse benzodiazepines. At 12 months, 140 (55.6%) of buprenorphine patients and 156 (61.9%) of methadone patients remained in treatment (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =.148). Patients on methadone had a higher mean number of opioid-negative months (6.96\u00a0vs. 5.43;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;.001) and mean number of months in treatment (9.38\u00a0vs. 8.59;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;.001). On multivariable analysis, methadone maintenance was significantly associated with successful treatment (adjusted odds ratio: 2.10; 95% confidence interval: 1.43\u20133.07).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Office-based buprenorphine and methadone maintenance programs serve very different populations. Both are effective, but patients on methadone had mildly better treatment outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1080\/08897077.2013.819828","type":"journal-article","created":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T14:51:52Z","timestamp":1373295112000},"page":"122-126","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":29,"title":["A Comparison of Characteristics and Outcomes of Opioid-Dependent Patients Initiating Office-Based Buprenorphine or Methadone Maintenance Treatment"],"prefix":"10.1177","volume":"35","author":[{"given":"Michael I.","family":"Fingerhood","sequence":"first","affiliation":[{"name":"Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Van L.","family":"King","sequence":"additional","affiliation":[{"name":"Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert K.","family":"Brooner","sequence":"additional","affiliation":[{"name":"Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darius A.","family":"Rastegar","sequence":"additional","affiliation":[{"name":"Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,4,1]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.8165"},{"key":"e_1_3_3_3_1","unstructured":"Substance Abuse and Mental Health Services Administration. Results From the 2010 National Survey on Drug Use and Health: Summary of National Findings. Rockville MD: Substance Abuse and Mental Health Services Administration; 2011. NSDUH Series H\u201341 HHS Publication No. (SMA) 11\u20134658."},{"key":"e_1_3_3_4_1","first-page":"1487","article-title":"Vital signs: overdoses of prescription opioid pain relievers\u2014United States, 1999\u20132008","volume":"60","author":"Centers for Disease Control and Prevention","year":"2011","unstructured":"Centers for Disease Control and Prevention. Vital signs: overdoses of prescription opioid pain relievers\u2014United States, 1999\u20132008. MMWR Morb Mort Wkly Rep. 2011;60:1487\u20131492.","journal-title":"MMWR Morb Mort Wkly Rep"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/10550887.2012.694598"},{"key":"e_1_3_3_6_1","doi-asserted-by":"crossref","unstructured":"Barnett PG Rodgers JH Bloch DA. A meta-analysis comparing buprenorphine to methadone for treatment of opiate dependence. 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