{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:18:20Z","timestamp":1777897100136,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Substance Abuse"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:p>Background: Despite the well-known effectiveness and widespread use of relapse prevention medications such as extended release naltrexone (XR-NTX) and buprenorphine for opioid addiction in adults, less is known about their use in younger populations. Methods: This was a naturalistic study using retrospective chart review of N = 56 serial admissions into a specialty community treatment program that featured the use of relapse prevention medications for young adults (19\u201326\u00a0years old) with opioid use disorders. Treatment outcomes over 24\u00a0weeks included retention and weekly opioid-negative urine tests. Results: Patients were of mean age 23.1, 70% male, 86% Caucasian, 82% with history of injection heroin use, and treated with either buprenorphine (77%) or XR-NTX (23%). The mean number of XR-NTX doses received was 4.1. Retention was approximately 65% at 12\u00a0weeks and 40% at 24\u00a0weeks, and rates of opioid-negative urine were 50% at 12\u00a0weeks and 39% at 24\u00a0weeks, with missing samples imputed as positive. There were no statistically significant differences in retention ( t = 1.87, P = .06) or in rates of weekly opioid-negative urine tests ( t = 1.96, P = .06) between medication groups, over the course of 24\u00a0weeks. The XR-NTX group had higher rates of weekly negative urine drug tests for other nonopioid substances ( t = 2.83, P &lt; .05) compared with the buprenorphine group. Males were retained in treatment longer and had higher rates of opioid-negative weeks compared with females. Conclusions: These results suggest that relapse prevention medications including both buprenorphine and XR-NTX can be effectively incorporated into standard community treatment for opioid addiction in young adults with good results. Specialty programming focused on opioid addiction in young adults may provide a promising model for further treatment development.<\/jats:p>","DOI":"10.1080\/08897077.2016.1143435","type":"journal-article","created":{"date-parts":[[2016,1,28]],"date-time":"2016-01-28T09:59:56Z","timestamp":1453975196000},"page":"392-397","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":28,"title":["Relapse Prevention Medications in Community Treatment for Young Adults with Opioid Addiction"],"prefix":"10.1177","volume":"37","author":[{"given":"Hoa T.","family":"Vo","sequence":"first","affiliation":[{"name":"Maryland Treatment Centers, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Robbins","sequence":"additional","affiliation":[{"name":"Maryland Treatment Centers, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meghan","family":"Westwood","sequence":"additional","affiliation":[{"name":"Maryland Treatment Centers, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debra","family":"Lezama","sequence":"additional","affiliation":[{"name":"Maryland Treatment Centers, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Fishman","sequence":"additional","affiliation":[{"name":"Maryland Treatment Centers, Baltimore, Maryland, USA"},{"name":"Johns Hopkins School of Medicine, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,1]]},"reference":[{"key":"bibr1-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1007\/s40272-013-0041-5"},{"key":"bibr2-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2008.574"},{"key":"bibr3-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2008.07.016"},{"key":"bibr4-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0000000000000035"},{"key":"bibr5-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1080\/08897077.2014.958208"},{"key":"bibr6-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2010.03015.x"},{"key":"bibr7-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1080\/13556210310001602257"},{"key":"bibr8-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2014.04.006"},{"key":"bibr9-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2012.12.010"},{"key":"bibr10-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0000000000000125"},{"key":"bibr11-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1402780"},{"key":"bibr12-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1111\/add.12333"},{"key":"bibr13-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2011.07.033"},{"key":"bibr14-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1046\/j.1360-0443.2003.00334.x"},{"key":"bibr15-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2011.08.001"},{"key":"bibr16-08897077.2016.1143435","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2009.02829.x"}],"container-title":["Substance Abuse"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/08897077.2016.1143435","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1080\/08897077.2016.1143435","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/08897077.2016.1143435","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T08:47:18Z","timestamp":1777625238000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1080\/08897077.2016.1143435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1080\/08897077.2016.1143435"],"URL":"https:\/\/doi.org\/10.1080\/08897077.2016.1143435","relation":{},"ISSN":["0889-7077","1547-0164"],"issn-type":[{"value":"0889-7077","type":"print"},{"value":"1547-0164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7]]}}}