{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T12:15:36Z","timestamp":1780488936490,"version":"3.54.1"},"reference-count":21,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"crossref","award":["R42DA041941"],"award-info":[{"award-number":["R42DA041941"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Substance Abuse"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Background<\/jats:italic>\n                    : Despite the clear success of office-based buprenorphine treatment in increasing availability of effective treatment for opioid use disorder, constraints on its effectiveness include high attrition and limited high-quality behavioral care in many areas. Web-based interventions may be a novel strategy for providing evidence-based behavioral care to individuals receiving office-based buprenorphine maintenance. This report describes modification and initial pilot testing of Web-based training in cognitive-behavioral therapy (CBT4CBT) specifically for use with individuals in office-based buprenorphine.\n                    <jats:italic toggle=\"yes\">Methods<\/jats:italic>\n                    : Twelve-week randomized pilot trial evaluating effects of CBT4CBT-Buprenophine in retaining participants and reducing drug use with respect to standard office-based buprenorphine alone was carried out. Twenty individuals meeting DSM-5 (\n                    <jats:italic toggle=\"yes\">Diagnostic and Statistical Manual of Mental Disorders, 5th Edition<\/jats:italic>\n                    ) criteria for current opioid use disorder were randomized to standard buprenorphine treatment or buprenorphine plus access to CBT4CBT-Buprenorphine.\n                    <jats:italic toggle=\"yes\">Results<\/jats:italic>\n                    : There were promising findings regarding rates of urine toxicology screens negative for opioids (91% versus 64%;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.05, effect size\n                    <jats:italic toggle=\"yes\">d<\/jats:italic>\n                    \u2009=\u20090.88) and all drugs (82% versus 30%;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.004,\n                    <jats:italic toggle=\"yes\">d\u2009=<\/jats:italic>\n                    \u20091.2). Individuals randomized to CBT4CBT-Buprenorphine completed a mean of 82.6 (SD\u2009=\u20094.4) days of treatment (of a possible 84) compared with 68.6 (SD\u2009=\u200932.6) for those assigned to standard buprenorphine treatment.\n                    <jats:italic toggle=\"yes\">Conclusions<\/jats:italic>\n                    : Although preliminary and limited by the small sample size, this trial suggests the feasibility and promise of validated, Web-based interventions, tailored for this specific patient population, for improving outcomes in office-based buprenorphine.\n                  <\/jats:p>","DOI":"10.1080\/08897077.2019.1569192","type":"journal-article","created":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T09:50:21Z","timestamp":1549273821000},"page":"132-135","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":39,"title":["Randomized Pilot Trial of Web-Based Cognitive-Behavioral Therapy Adapted for Use in Office-Based Buprenorphine Maintenance"],"prefix":"10.1177","volume":"40","author":[{"given":"Julia M.","family":"Shi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA;"},{"name":"Central Medical Unit, The APT Foundation, New Haven, Connecticut, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan P.","family":"Henry","sequence":"additional","affiliation":[{"name":"Central Medical Unit, The APT Foundation, New Haven, Connecticut, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie L.","family":"Dwy","sequence":"additional","affiliation":[{"name":"Central Medical Unit, The APT Foundation, New Haven, Connecticut, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Skye A.","family":"Orazietti","sequence":"additional","affiliation":[{"name":"Central Medical Unit, The APT Foundation, New Haven, Connecticut, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen M.","family":"Carroll","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA;"},{"name":"Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,4,1]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32893-3"},{"key":"e_1_3_4_3_2","first-page":"CD002207","article-title":"Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence","volume":"2","author":"Mattick RP","year":"2014","unstructured":"Mattick RP, , Breen C, , Kimber J, , Davoli M. 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