{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T13:13:16Z","timestamp":1780492396151,"version":"3.54.1"},"reference-count":14,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Substance Abuse"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Overdose deaths as a result of untreated opioid use disorder (OUD) pose a major public health concern across North America. Although slow-release oral morphine (SROM) is increasingly used as an alternative option for the treatment of OUD, research on its efficacy among individuals exposed to illicit fentanyl or those with previous unsuccessful attempts with other opioid agonist therapies (OATs) is limited and controversial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case<\/jats:title>\n                    <jats:p>We present a case of a 48-year-old male with severe OUD seeking treatment following a near-fatal fentanyl overdose. His previous treatment attempts with methadone and buprenorphine\/naloxone-based OAT had been unsuccessful. As per local guidelines, he was started on SROM with subsequent cessation of opioid cravings and illicit drug use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"discussion\">\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This case report describes a patient entering early remission for OUD when treated with SROM following unsuccessful past treatment attempts on first-line oral medications. Future studies should seek to evaluate SROM-based OAT as a potential second-line treatment alternative for OUD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1080\/08897077.2019.1576086","type":"journal-article","created":{"date-parts":[[2019,3,4]],"date-time":"2019-03-04T08:20:11Z","timestamp":1551687611000},"page":"473-475","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Successful Treatment with Slow-Release Oral Morphine following Afentanyl-Related Overdose: A Case Report"],"prefix":"10.1177","volume":"40","author":[{"given":"Gerrit","family":"Prinsloo","sequence":"first","affiliation":[{"name":"British Columbia Centre on Substance Use, Vancouver, British Columbia, Canada;"},{"name":"Department of Family Practice, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Ahamad","sequence":"additional","affiliation":[{"name":"British Columbia Centre on Substance Use, Vancouver, British Columbia, Canada;"},{"name":"Department of Family Practice, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2556-7049","authenticated-orcid":false,"given":"M. Eugenia","family":"Soc\u00edas","sequence":"additional","affiliation":[{"name":"British Columbia Centre on Substance Use, Vancouver, British Columbia, Canada;"},{"name":"Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,10,1]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6712a1"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/HRP.0000000000000075"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2013.07.001"},{"key":"e_1_3_4_5_2","volume-title":"A Guideline for the Clinical Management of Opioid Use Disorder.","year":"2017","unstructured":"A Guideline for the Clinical Management of Opioid Use Disorder. Vancouver, BC, Canada: British Columbia Centre on Substance Use (BCCSU); 2017. http:\/\/www.bccsu.ca\/wp-content\/uploads\/2017\/02\/BC-OUD-Guidelines_FINAL.pdf. Accessed January 4, 2018."},{"key":"e_1_3_4_6_2","unstructured":"Sustained release oral morphine injectable hydromorphone and Prescription Diacetylmorphine for Opioid Use Disorder: Clinical and Cost effectiveness and guidelines. CADTH rapid response report: summary of abstracts. Ottawa ON Canada: CADTH; 2017. https:\/\/www.cadth.ca\/sustained-release-oral-morphine-injectable-hydromorphone-and-prescription-diacetylmorphine-opioid-0. 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Cochrane Database Syst Rev. 2013;(6):CD009879.","journal-title":"Cochrane Database Syst Rev."},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2014.05.012"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/JCP.0000000000000288"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1159\/000368572"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.7326\/M17-2373"}],"container-title":["Substance Abuse"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/08897077.2019.1576086","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1080\/08897077.2019.1576086","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1080\/08897077.2019.1576086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T12:44:45Z","timestamp":1780490685000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1080\/08897077.2019.1576086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1080\/08897077.2019.1576086"],"URL":"https:\/\/doi.org\/10.1080\/08897077.2019.1576086","relation":{},"ISSN":["0889-7077","1547-0164"],"issn-type":[{"value":"0889-7077","type":"print"},{"value":"1547-0164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10]]}}}