{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:42:30Z","timestamp":1792608150576,"version":"4.5.0"},"reference-count":35,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Liposome Research"],"published-print":{"date-parts":[[2025,7,3]]},"DOI":"10.1080\/08982104.2025.2498956","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T13:29:58Z","timestamp":1746451798000},"page":"300-311","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":3,"title":["Optimization of PEGylation for cationic triacyl lipid-based siRNA lipoplexes prepared using the modified ethanol injection method for tumor therapy"],"prefix":"10.1080","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4731-0407","authenticated-orcid":false,"given":"Yoshiyuki","family":"Hattori","sequence":"first","affiliation":[{"name":"Department of Molecular Pharmaceutics, Hoshi University","place":["Shinagawa, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizuki","family":"Shinkawa","sequence":"additional","affiliation":[{"name":"Department of Molecular Pharmaceutics, Hoshi University","place":["Shinagawa, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Kurihara","sequence":"additional","affiliation":[{"name":"Department of Molecular Pharmaceutics, Hoshi University","place":["Shinagawa, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryohei","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Molecular Pharmaceutics, Hoshi University","place":["Shinagawa, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,5,5]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-083012-130404"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-010-9210-4"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/1061186X.2012.719232"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3301460"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3301705"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2017.03.001"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2016.08.058"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2015.09.012"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.b13-00059"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2017.1388451"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.11.056"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2020.11525"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1039\/d2bm01846b"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-0127"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcph.1553"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15020597"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2022.103635"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2024.106000"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2023.13067"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2017.5060"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.3892\/br.2024.1903"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2008.73"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2022.12769"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1208272"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2016.10.003"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-2131"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-16394-2"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.4161\/cc.11.3.19076"},{"issue":"11","key":"e_1_3_5_30_1","first-page":"1395","article-title":"Normal p53 status and function despite the development of drug resistance in human breast cancer cells","volume":"6","author":"Wosikowski K","year":"1995","unstructured":"Wosikowski K, Regis JT, Robey RW, et\u00a0al. Normal p53 status and function despite the development of drug resistance in human breast cancer cells. Cell Growth Differ. 1995;6(11):1395\u20131403.","journal-title":"Cell Growth Differ"},{"issue":"15","key":"e_1_3_5_31_1","first-page":"4196","article-title":"Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines","volume":"52","author":"Yaginuma Y","year":"1992","unstructured":"Yaginuma Y, Westphal H. Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines. Cancer Res. 1992;52(15):4196\u20134199.","journal-title":"Cancer Res"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.22556"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.77.2.1551-1563.2003"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi9602019"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0005-2736(02)00496-0"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.b19-00032"}],"container-title":["Journal of Liposome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/08982104.2025.2498956","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T16:37:14Z","timestamp":1756485434000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/08982104.2025.2498956"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,5]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,7,3]]}},"alternative-id":["10.1080\/08982104.2025.2498956"],"URL":"https:\/\/doi.org\/10.1080\/08982104.2025.2498956","relation":{},"ISSN":["0898-2104","1532-2394"],"issn-type":[{"value":"0898-2104","type":"print"},{"value":"1532-2394","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,5]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ilpr20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ilpr20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-03-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-21","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}