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Abrus cantoniensis, Citrus medica, Dioscorea collettii, and Polygonum multiflorum exhibited 100% activity and were selected for further evaluation by applying five solvents (petroleum ether, chloroform, ethyl acetate, methanol, and water) for the extraction of the samples, followed by an in vivo bioassay. Among the plants tested, water, methanol, and ethyl-acetate extracts of P. multiflorum showed the highest efficacies; EC50 values (median concentration that results in 50% of its maximal effect) were 1.9, 5.4, and 9.1 mg\/L, respectively, and extracts showed 100% efficacy against Dactylogyrus intermedius at 100, 12.5, and 25 mg\/L. This was followed by ethyl-acetate, chloroform, and methanol extracts of Dioscorea collettii, which demonstrated 100% efficacy at 80, 80, and 120 mg\/L and had EC50 values of 19.7, 27.1, and 37.8 mg\/L, respectively, after 48 h of exposure. Chloroform and ethyl-acetate extracts of C. medica, which exhibited 100% efficacy against Dactylogyrus intermedius at 100 and 125 mg\/L, revealed similar activity and had EC50 values of 58.7 and 51.3 mg\/L, respectively. The ethyl-acetate and methanol extracts of A. cantoniensis exhibited the lowest activity and had EC50 values of 279.4 and 64.3 mg\/L. Acute toxicities of these active extracts were investigated on Goldfish for 48 h. The findings indicated that extracts of the four plants can be developed as a preferred natural antiparasitic for the control of D. intermedius.<\/jats:p>\n               <jats:p>Received June 15, 2013; accepted February 11, 2014<\/jats:p>","DOI":"10.1080\/08997659.2014.902872","type":"journal-article","created":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T20:19:11Z","timestamp":1410985151000},"page":"127-136","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":15,"title":["Screening Medicinal Plants for Use against <i>Dactylogyrus intermedius<\/i> (Monogenea) Infection in Goldfish"],"prefix":"10.1093","volume":"26","author":[{"given":"Yang","family":"Hu","sequence":"first","affiliation":[{"name":"College of Science, Northwest A&F University, Yangling, 712100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Ji","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Ling","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhe","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Lu","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qizhong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Hydrobiology, Jinan University, Engineering Research Center of Tropical and Subtropical Aquatic Ecological Engineering Minister of Education, Key Laboratory of Aquatic Eutrophication and Control of Harmful Algal Blooms of Guangdong Higher Education Institutes, Guangzhou, 510632, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaoxue","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Science, Northwest A&F University Yangling 712100 China"},{"name":"College of Animal Science and Technology, Northwest A&F University Yangling 712100 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,7,3]]},"reference":[{"key":"2025011310270319800_CIT0001","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.vetpar.2005.07.005","article-title":"Disease and health management in Asian aquaculture","volume":"132","author":"Bondad-Reantaso","year":"2005","journal-title":"Veterinary Parasitology"},{"key":"2025011310270319800_CIT0002","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0044-8486(93)90276-5","article-title":"Epidemiology of gill parasite infections in Cyprinus carpio in Indonesia and possible control methods","volume":"118","author":"Buchmann","year":"1993","journal-title":"Aquaculture"},{"key":"2025011310270319800_CIT0003","first-page":"418","article-title":"The inhibitory effect of Abrus cantoniensis Hance on Hepatitis B virus in vitro","volume":"28","author":"Chen","year":"2009","journal-title":"Herald of Medicine"},{"key":"2025011310270319800_CIT0004","first-page":"39","article-title":"Study on the antibacterial activities of the ethanol extracts of Abrus cantoniensis","volume":"2","author":"Cheng","year":"2006","journal-title":"Research and Practice on Chinese Medicines"},{"key":"2025011310270319800_CIT0005","volume-title":"Pharmacopoeia of the People's Republic of China (the first division of 2005 edition)","author":"China Pharmacopoeia Committee","year":"2004"},{"key":"2025011310270319800_CIT0006","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/ptr.2077","article-title":"In vitro activities of Citrus medica L. cv. 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