{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:17:51Z","timestamp":1740140271198,"version":"3.37.3"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2017,7,5]],"date-time":"2017-07-05T00:00:00Z","timestamp":1499212800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A 480-g flowerhorn cichlid (an ornamental hybrid) with severe bilateral abdominal swelling, bulla-like structures on the skin, bilateral exophthalmia, and a prolapsed intestine was presented. Radiographs showed compression of the posterior part of the swim bladder and abdominal distention. Ultrasonography of visceral organs revealed a heterogeneous mass with hypoechoic to anechoic polycystic parenchyma and free fluid in the abdominal cavity. At necropsy, free fluid in the abdominal cavity and a large polycystic mass originating from the posterior kidney were observed. Histologically, the mass was composed of more cystic growth of tubules. The renal architecture was replaced by tubules, often irregular in shape, lined by simple to lightly stratified layers of neoplastic and pleomorphic cuboidal to columnar epithelial cells and the absence of glomeruli. Birefringent crystals were observed with polarized light within the lumen of some tubules. The apical border of the neoplastic cells was periodic acid\u2013Schiff positive. Immunohistochemically, the neoplastic cells were positive for cytokeratin AE1\/AE3 and proliferating cell nuclear antigen and were negative for p53 (tumor suppressor protein). Microscopic metastasis was seen in the spleen. The metastatic tumor was classified as a cystic adenocarcinoma of the kidney, originating from the proximal tubules.<\/jats:p>\n               <jats:p>Received October 7, 2016; accepted June 18, 2017 Published online July 31, 2017<\/jats:p>","DOI":"10.1080\/08997659.2017.1349008","type":"journal-article","created":{"date-parts":[[2017,7,5]],"date-time":"2017-07-05T21:09:32Z","timestamp":1499288972000},"page":"158-164","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":5,"title":["Renal Cystic Adenocarcinoma in a Flowerhorn Cichlid with Metastatic Involvement of the Spleen"],"prefix":"10.1093","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1007-6282","authenticated-orcid":false,"given":"Hooman","family":"Rahmati-Holasoo","sequence":"first","affiliation":[{"name":"Department of Aquatic Animal Health, Faculty of Veterinary Medicine, University of Tehran, Post Office Box 14155-6453, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Shokrpoor","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Veterinary Medicine, University of Tehran, Post Office Box 14155-6453, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majid","family":"Masoudifard","sequence":"additional","affiliation":[{"name":"Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Post Office Box 14155-6453, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HosseinAli","family":"Ebrahimzadeh Mousavi","sequence":"additional","affiliation":[{"name":"Department of Aquatic Animal Health, Faculty of Veterinary Medicine, University of Tehran, Post Office Box 14155-6453, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Haddadi","sequence":"additional","affiliation":[{"name":"Department of Aquatic Animal Health, Faculty of Veterinary Medicine, University of Tehran, Post Office Box 14155-6453, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Tavakkoli","sequence":"additional","affiliation":[{"name":"Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Post Office Box 14155-6453, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,7,5]]},"reference":[{"key":"2025011310283020800_CIT0001","first-page":"27","article-title":"The diagnostic value of cytokeratins expression in the renal parenchyma tumors","volume":"51","author":"Alexa","year":"2010","journal-title":"Romanian Journal of Morphology and Embryology"},{"key":"2025011310283020800_CIT0002","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1365-2761.2007.00871.x","article-title":"Molecular markers of cancer in cartilaginous fish: immunocytochemical study of PCNA, 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