{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:31:23Z","timestamp":1759336283971,"version":"3.37.3"},"reference-count":46,"publisher":"Informa UK Limited","issue":"7","license":[{"start":{"date-parts":[[2015,7,3]],"date-time":"2015-07-03T00:00:00Z","timestamp":1435881600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100008732","name":"Uehara Memorial Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100008732","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We investigated the effect of daidzein feeding and estradiol treatment on food intake in cholecystokinin-1 receptor (CCK1R) deficiency, leptin receptor (ObRb) deficiency rats and their wild-type rats. These rats underwent an ovariectomy or a sham operation. For the 5 week experiment, each rat was divided in three groups: control, daidzein (150\u00a0mg\/kg diet), and estradiol (4.2\u00a0\u03bcg\/rat\/day) groups. In both CCK1R+ and CCK1R\u2212 rats, daidzein feeding and estradiol treatment significantly decreased food intake. Daidzein feeding significantly reduced food intake in ovariectomized ObRb\u2212 rats, although not in ObRb+ rats. Estradiol treatment significantly lowered food intake in ovariectomized ObRb+ and ObRb\u2212 rats. In the ovariectomized rats, estradiol treatment significantly increases uterine weight, while daidzein feeding did not change it, suggesting that daidzein might have no or weak estrogenic effect in our experiment. These results suggest that CCK1R and ObRb signalings were not essential for the daidzein- and estradiol-induced anorectic action.<\/jats:p>","DOI":"10.1080\/09168451.2015.1018123","type":"journal-article","created":{"date-parts":[[2015,3,13]],"date-time":"2015-03-13T09:24:49Z","timestamp":1426238689000},"page":"1164-1171","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":10,"title":["The daidzein- and estradiol- induced anorectic action in CCK or leptin receptor deficiency rats"],"prefix":"10.1080","volume":"79","author":[{"given":"Mina","family":"Fujitani","sequence":"first","affiliation":[{"name":"Laboratory of Nutrition Science, Faculty of Agriculture, Department of Biological Resources, Ehime University, Matsuyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takafumi","family":"Mizushige","sequence":"additional","affiliation":[{"name":"Laboratory of Nutrition Science, Faculty of Agriculture, Department of Biological Resources, Ehime University, Matsuyama, Japan"},{"name":"Faculty of Agriculture, Department of Applied Biological Chemistry, Utsunomiya University, 350 Minemachi, Utsunomiya Tochigi 321\u20138505, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keshab","family":"Bhattarai","sequence":"additional","affiliation":[{"name":"Laboratory of Nutrition Science, Faculty of Agriculture, Department of Biological Resources, Ehime University, Matsuyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asami","family":"Iwahara","sequence":"additional","affiliation":[{"name":"Laboratory of Nutrition Science, Faculty of Agriculture, Department of Biological Resources, Ehime University, Matsuyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryojiro","family":"Aida","sequence":"additional","affiliation":[{"name":"Laboratory of Nutrition Science, Faculty of Agriculture, Department of Biological Resources, Ehime University, Matsuyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taro","family":"Kishida","sequence":"additional","affiliation":[{"name":"Laboratory of Nutrition Science, Faculty of Agriculture, Department of Biological Resources, Ehime University, Matsuyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2015,7,3]]},"reference":[{"key":"2021033107585442400_CIT0001","doi-asserted-by":"publisher","first-page":"95","DOI":"10.3109\/07853899709113696","article-title":"Phyto-oestrogens and Western diseases","volume":"29","author":"Adlercreutz","year":"1997","journal-title":"Ann. 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