{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,6,10]],"date-time":"2022-06-10T17:36:08Z","timestamp":1654882568263},"reference-count":6,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2017,1,2]],"date-time":"2017-01-02T00:00:00Z","timestamp":1483315200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,1,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Professor Satoshi \u014cmura was awarded the 2015 Nobel Prize in Physiology or Medicine. He is the third to win the award for research on antibiotic, following Fleming\u2019 (UK, 1945, discovery of penicillin) and Waksman (USA, 1952, discovery of streptomycin), and the second person after Waksman to receive the award for research on actinomycetes. By focusing his research on macrolides stemming from leucomycin research rather than \u03b2-lactams like penicillin or aminoglycosides like streptomycin, Prof. \u014cmura realized many scientific achievements. These efforts finally led to the discovery of avermectin and its semi-synthetic derivative, ivermectin, considered a monumental contribution to the human race. In this manuscript, I will outline the chronicles of the epoch-making antibiotic exploratory researches preceding Prof. \u014cmura.<\/jats:p>","DOI":"10.1080\/09168451.2016.1248372","type":"journal-article","created":{"date-parts":[[2016,11,25]],"date-time":"2016-11-25T10:41:31Z","timestamp":1480070491000},"page":"23-27","update-policy":"http:\/\/dx.doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["Epoch-making milestones in antibiotic exploratory researches in Japan\u2020"],"prefix":"10.1080","volume":"81","author":[{"given":"Kunimoto","family":"Hotta","sequence":"first","affiliation":[{"name":"Functional Water Foundation, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2017,1,2]]},"reference":[{"key":"2021033114473679400_CIT0001","first-page":"179","article-title":"A historical story of the Japanese antibiotics world-development of penicillin","volume":"63","author":"Hotta","year":"2010","journal-title":"Jpn J Antibiot"},{"key":"2021033114473679400_CIT0002","unstructured":"The Society for Actinomycetes Japan [Living with Actinomycetes] [in Japanese]\n          . Tokyo: Mimizuku-sha; 2011."},{"key":"2021033114473679400_CIT0003","unstructured":"Iijima \u00a0M\n          , translator. Selman Waksman\u2019s autobiography My life with the Microbes. Tokyo: Shinhyoron Publishing Inc.; 1955."},{"key":"2021033114473679400_CIT0004","unstructured":"http:\/\/www.waksman.or.jp\/"},{"key":"2021033114473679400_CIT0005","unstructured":"Nagai \u00a0K\n          , editor. Seimei ni Miserareta Kenkyushatachi [Researchers Attracted by Life] [in Japanese]. Tokyo: Igaku Shuppan Center; 1995. p. \n16\u201329."},{"key":"2021033114473679400_CIT0006","unstructured":"Kagawa \u00a0F\n          . Rosajin to Kage no MeikoToko Matsushima Hiroaki Shogai [Rosanjin and a Hidden Craftsman-The Life of a Potter, Hiroaki Matsushima] [in Japanese]. Tokyo: Oscarart; 1990."}],"container-title":["Bioscience, Biotechnology, and Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/bbb\/article-pdf\/81\/1\/23\/36839383\/bbb0023.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/bbb\/article-pdf\/81\/1\/23\/36839383\/bbb0023.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T11:51:17Z","timestamp":1654602677000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bbb\/article\/81\/1\/23\/5938821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,2]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,1,2]]},"published-print":{"date-parts":[[2017,1,2]]}},"URL":"https:\/\/doi.org\/10.1080\/09168451.2016.1248372","relation":{},"ISSN":["0916-8451","1347-6947"],"issn-type":[{"value":"0916-8451","type":"print"},{"value":"1347-6947","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,1,2]]},"published":{"date-parts":[[2017,1,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbbb20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbbb20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-10-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-11-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}