{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T12:10:04Z","timestamp":1769515804739,"version":"3.49.0"},"reference-count":27,"publisher":"Informa UK Limited","issue":"5","license":[{"start":{"date-parts":[[2017,5,4]],"date-time":"2017-05-04T00:00:00Z","timestamp":1493856000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100002642","name":"Korea University","doi-asserted-by":"publisher","award":["KU-12-0322"],"award-info":[{"award-number":["KU-12-0322"]}],"id":[{"id":"10.13039\/501100002642","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002642","name":"Korea University","doi-asserted-by":"publisher","award":["KU-12-0322"],"award-info":[{"award-number":["KU-12-0322"]}],"id":[{"id":"10.13039\/501100002642","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,5,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Excessive body fat accumulation can result in obesity, which is a serious health concern. Kefir, a probiotic, has recently shown possible health benefits in fighting obesity. This study investigated the inhibitory effects of 0.1 and 0.2% kefir powder on fat accumulation in adipose and liver tissues of high-fat diet (HFD)-induced obese mice. Kefir reduced body weight and epididymal fat pad weight and decreased adipocyte diameters in HFD-induced obese mice. This was supported by decreased expression of genes related to adipogenesis and lipogenesis as well as reduced proinflammatory marker levels in epididymal fat. Along with reduced hepatic triacylglycerol concentrations and serum alanine transaminase and aspartate transaminase activities, genes related to lipogenesis and fatty acid oxidation were downregulated and upregulated, respectively, in liver tissue. Kefir also decreased serum triacylglycerol, total cholesterol, and low-density lipoprotein\u2013cholesterol concentrations. Overall, kefir has the potential to prevent obesity.<\/jats:p>","DOI":"10.1080\/09168451.2016.1258984","type":"journal-article","created":{"date-parts":[[2017,1,23]],"date-time":"2017-01-23T09:36:06Z","timestamp":1485164166000},"page":"958-965","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":36,"title":["Kefir prevented excess fat accumulation in diet-induced obese mice"],"prefix":"10.1080","volume":"81","author":[{"given":"Jae-Woo","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Food and Biotechnology, Korea University, Sejong, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Won","family":"Kang","sequence":"additional","affiliation":[{"name":"Food and Nutritional Sciences, Department of Family and Consumer Sciences, North Carolina Agricultural and Technical State University, Greensboro, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won-Chul","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Food and Biotechnology, Korea University, Sejong, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi-Kyoung","family":"Kim","sequence":"additional","affiliation":[{"name":"Naturene Co. 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